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10 Feb 2009
Brand:Sotret
Weight:90Kg = 200lbs
Sex:Male
Age:48
Dosage:20mg once daily
New behavior: No soda pop of any kind

Day 5:
Well I took my 4th pill last night. I know it sounds crazy but I can see changes already. I have even more fear of this drug than I had in the first place. It has to be powerful to have these effects in the short term. I definitely am waking up with less oil on my face. My first day of work was met with 50 percent less blotting with tissues. I had several events where I felt I had flushed (rosaceans pay heed) under some job stress but checking in the bathroom showed just regular looking skin. My Acne has not burst forth in the abscence antibiotics yet. Pores seem slightly smaller already. The mild lip drying is still present. I have no reported side effects with the possible exception of the lip drying and maybe one other. My libido seems to have taken several steps backwards. It should be noted that all of the results I am reporting could be due to just coincendental factors. Inside though, I really think it is this drug. I have read other Accutane logs with similar results. I am trying to be very objective, I pay attention to small details. One other thing that is definitely happening is the anti-imflammatory effect. My skin color is more even and red veined areas are looking less apparent than they have in years. I realize this is only 80 milligrams of Accutane and the diet changes could be part of this...... I don't know. It seems impossible to already be feeling the effects of this drug, but my oil ouput and skin color has shown changes. I know, I have to look in the mirror every day. I will continue to log results, I expect the suspected effects to become more apparent as time goes on. Then I can report with more confidence what I am already suspecting. I remain mildly optimistic wondering about what I am experiencing. I am thinking of asking my Derm to reduce the dosage to 10mg.

Best Wishes
LowTane

Declarative statement: I am not recommending this drug. I am only reporting results in the most objective manner I can muster. I do believe this drug can be dangerous. I am taking this risk of my own accord. Please read other blogs that discuss the seriousness of possible long term side effects.
11 Feb 2009
Brand:Sotret
Weight:90Kg = 200lbs
Sex:Male
Age:48
Dosage:20mg once daily
New behavior:None today

Day 6:
Well, I will be taking my 6th pill in a few minutes. I gotta tell ya, you probably won't believe me though. My pores which I double checked with my Wife are reduced by over 50 percent. I was blotting 10 times a day with tissues to soak up oil. I now blot 4 to 5 times a day during work. My acne was under control from a year on Doxycycline, so I didn't have much when I started Accutane. However, by now I should be breaking out gang busters with Acne Vulgaris all over my nose. Ususally my nose is throbbing from the swollen sebaceous glands. It is feeling of normal size again. It actually looks smaller. It is like a switch has been thrown and my oil glands are being told to stop. My pores are shrinking at a rapid rate. A 100mg dose (20mg once a day) of this drug has caused these reactions in only 5 days. I say it again, I am very scared of a drug that has this powerful effect in that period of time. To the rosaceans who may be vieiwing this log, I feel extreme hot flushes in the cheek but not my nose, however when I check to see how bad it is, it is insignificant. I look mildly flushed compared to how I used to look. My side effects are extremely mild to none. Slightly dry upper lip is all I have..... I have read many horror stories about this drug, I won't go into the details. So, my fear levels are high. I am happy and at the same time scared to death. I really want to take even lower doses. I have considered getting gelatin caps and a syringe and drawing out 5mg doses to put in the caps. I wished this came in pill form so I could break them into pieces. I am not sure what I am going to do yet. It almost feels as if my body needed this, it makes me wonder how it works. Its like something out of whack has been corrected. Some individuals lives are ruined by this drug. I find that it is the high dosers who report the worst problems. Low dose this drug might just be heaven sent. My job is already one hundred percent better. My wife is throwing a party this weekend and I am actually looking forward to it. Miracle or curse......we shall see.:confused:

Declarative statement: I am not recommending this drug. I am only reporting results in the most objective manner I can muster. I do believe this drug can be dangerous. I am taking this risk of my own accord. Please read other blogs that discuss the seriousness of possible long term side effects.

Best Wishes
LowTane
12 Feb 2009
Brand:Sotret
Weight:90Kg = 200lbs
Sex:Male
Age:48
Dosage:20mg once daily
New behavior:None today


Day 7:
I have had mild rosy cheeks and nose today every so often. Once for an hour or so. I do believe that the magic dose for my rosacea symptoms is probably lower. Most Rosacea forums report success with low doses. The trick is if you have both Acne Vulgaris and Rosacea to find a dose that is just right for both afflictions. Low dose studies show that 2.5 to 10 milligrams for varying sizes of people seems to work very well for Rosacea. Low dose studies for Acne seem to hover around 10 to 20 milligrams for varying sizes of people. I am going to ask for a reduction to 10 milligrams this month when I see my Derm. My skin is already looking better just because of the greasiness being minimized. Pores aren't so hideous. If this drug has this affect this soon, I wonder how fast things could go bad if I stopped taking it right now? The throbbing swollen feeling my nose has had for years is minimal now. Skin is dry and feeling smoother already. My wife has noticed the difference too. I kid you not, this is like a biological switch has been thrown. I have been waiting for the acne to explode, so far nothing. If I don't explode in another week with acne I will begin to believe that Accutane is suppressing the bacteria that causes acne somehow. Well for now I will stay on this dosage. It is so early in this trial that some readers must think I am nuts and imagining the results. I have considered that maybe I am just hitting one of those acne free windows and this is a coincedence. One thing I have noticed is the parts of my face that are not normally oily are very dry and smooth. My whole face feels tight. I am using Cetaphil on my cheeks. If my Derm won't go for a reduction in dosage I may move to skip dosing and take 20mg every other day. Well thats all for now, gotta go take pill number 7.
:wave:

Ps. I mentioned a Libido scare a few posts ago, well it checks out fine. (Well, for a 48 year old anyways!) ;)

Best Wishes
LowTane
22 Feb 2009
Brand:Sotret
Weight:90Kg = 200lbs
Sex:Male
Age:48
Dosage:20mg once daily
Symptom: Dry lower lip & Minor skin flaking on the nose.


Day 17: Well this report will be a summary of events upto this time. I have experienced no significant side effects from this low dosage of Accutane. I am taking the Sotret brand. My lower lip is just barely dry. Every now and then I have a little piece of skin on my lip get dry enough to peel off with my teeth. This is rare, now this is significant. If you haven't seen what "high dosers" go through you need to go surf and read. Then again, I may not get the successful remission that high dosers may get. Now for the good part. My life has been so positively affected that I am shocked. My attitude, my willingness to participate in life. My students have noticed the difference, I am having fun teaching again. My personal space when talking to people has gotten to a normal distance again. I am not blotting during the day more than once or twice. I can touch my nose and my fingers don't feel greasy. My zits are coming and going at a rapid rate. My red blotchy appearance is showing a more even normal colored skin tone. Pores I thought were going to take plastic surgery have shrunk by 65%. My nose dosen't feel swollen anymore. My rosacea symptoms are non-existent. Veins in my nose have dissappeared. What can I say, I am hooked on Acctuane. My quality of life has already improved by 80% in just a little over two weeks on this miraculous drug. I can't tell you how this makes me feel, what an amazing experience it has been already. So, there.... thats how I feel today. I wished to God I had tried this drug a lot earlier, before I had so much scarring. Oh well... maybe laser will finish this journey off it I get a good remission. Well, folks...I recommend a low dose experience, even lower than mine. Possibly microdose will be the way of the future. 2.5 milligrams total daily. Like a supplement, who knows. Well, pill #17 is on deck. I will take it with milk to increase the absorbtion. It is fat soluable..............:p


Best Wishes
LowTane
Well Lowtane, I will post a few here and there. I am taking 40mg per day of Claravis. I have taken 7 doses so far. I take mine at night, after dinner. Days 3 through 5 resulted in some breakouts, but quite frankly no more intense than when I was on tetracycline and lotions, and they are less painful and shorter lived. No issue with sex drive yet, and besides, they make pills for that too! I continue not to drink alcohol. I drink plenty of water. I have a dry lower lip, and some redness and tightening of the face. No other side effects, except maybe that i do not seem too hungry during the day and I am starving at night. I, too, feel like I am getting my life back. My nose is less swollen and pores are smaller. I, too, wish I did this years ago, but even at age 48 I am still happy to do it now. Those who do not have these problems have no idea.
25 Feb 2009
Brand:Sotret
Weight:90Kg = 200lbs
Sex:Male
Age:48
Dosage:20mg once daily

Day 21 cont-
Allrighty then...... update on the sex drive post. Now mind you my moral beliefs prohibit some things. So this is tough for me.. Further attempts to utlize my natural processes met with success. I will continue to check on this capability throughout my Accutane course and after my prescription is complete. It is possible that I have read far to much material regarding the usage of this drug. I may be psyching myself out. Intimacy is such a mental event. It should be noted that 5 million people have now taken this drug. You would think there would be more on impotence if it was prevalent. I still do believe that individuals that have reported impotence are telling the truth. Things have changed in my body. I may have psyched myself out or maybe not. To early to tell. If you are following this thread you should also remember this evidence is anecdotal at best, and the reported experiences of just one person. I am not a health care professional and have had no formal training whatsoever. So, I will just try and be honest with what I experience as it happens. I will continue to closely monitor this aspect of this therapy. I apologize if I have offended anyone, I am trying to be as discreet as possible for both women and men who may read this thread. But, hair falling out, impotence, depression and a myriad of other side effects reported by individuals who have used Accutane warrant this level of reporting. The issue is not temporary impotence, its permanent impotence that has me freaked. Some individuals have reported this effect even after stopping Accutane. I don't trust big pharma or doctors implicitly. My wife and I value our intimate relationship and I don't believe I wish to trade it for a clear face. So hang in there, I will report daily to the best of my ability any notable changes that may occur. So for now the libido outcome is still on hold.

Ps. My wife says it looks like I had a nose job, I didn't realize how swollen it was from all the excess sebaceous activity.

Keep the faith!
LowTane :p
26 Feb 2009
Brand:Sotret
Weight:90Kg = 200lbs
Sex:Male
Age:48
Dosage:20mg once daily
Symptoms:Lower lip is a lot dryer than before. Cracking a little now.

Day 22:

Applied carmex to the lower lip and it worked like a charm. Face is now almost 100% clear. Blotches are fading and oil is gone. I am happy to say that all biological processes are working just fine. My blood test is coming up quick I am hoping cholesterol and triglycerides are acceptable. Can't forget liver enzymes too...... I am thinking that maybe the libido is going to be okay. I think that I have never been so concerned about a medication before and it may be causing some over reaction to normal events. We shall see. All of the horror stories on the web have impacted my psyche. I need to keep this in perspective. 5 million users, less than a hundred examples of web posts discussing permanently lost libidos. I hope I haven't freaked out any potential Accutane users at this point. If I did I apologize, if things do fail in the future I will try to alert blog readers to the problems in a sober manner. I will closely scrutinize all aspects of my body during the entire Accutane regimen. I will keep you posted.

Best Wishes
LowTane
Hi Drew25.

The redness did get worse, especially on days 3 through 5. Then, it started to get better. Now after 11 doses the redness is markedly improved from what it was before I started. The oil is virtually gone, although like Lowtane, I check out of habit every few hours. I am starting to break out a bit more the last 24 hours, but the stubborn hard bumps that 2 weeks ago would have meant a 3 week sentence now break easy and wer virtually gone overnight, leaving only some discoloration and minor peeling. Be care about the peeling if it happens to you because pulling off the dried skin for me results in some red and tender areas, more like an abrasion than anything else, and I noticed that the disoloration lasts longer from this activity. I take my pill with dinner, which for me is about 7:30. I notice that I am not very hungry during the day, but when I start to eat dinner I am famished and eat a larger meal than before. Then, by 9:30, I am very tired. I sleep very well for about 4 hours, wake up in the middle of the night ready to go, then within an hour I conk out and the next thing I know the alarm is going off at 5:40. Not a good sleeping pattern, but I`ll take it. Good luck to you.

And LowTane, I must say I am hooked on your postings. I don`t check this on weekends, but I look forward to reading about your progress on Monday.

Regards to all.
"Generally accutane is introduced at a very low dose and is steadily increased over many weeks. There actually are no specific guidelines as to how much should be prescribed to each person. However, research shows that a total dose of around 120mg per kilogram of an individualís body weight is enough to banish acne for some time. "

OK, well if I do the math, I will need to take about 10,300 mgs to be "cured." That would be an average of about 57.25 mgs per day for 6 months. I am taking 40 mgs per day now, and I know I won`t be on that level for the 9 months it would take to reach optimum dosage. My guess is I will do a few months at 60 to 80mgs per day once the docs confirm my body has tolerated the lower dosage so well. My daughter, who weighs 110, did most months at 20mg and a few at 40mg, when the 20 stopped showing improvement. They cut her back down to 20mg before she finished.

Anyway, I go back to the doc in 2 weeks....bloodtest next week. I assume I will be ok with blood levels and enzymes. I am not ready to drink alcohol yet, because I don`t want to risk a bad test result (oh yeah, or my liver). At 14 doses in as of last night, I figure I am about 1/12 there! I am measuring this ride in terms of days, not mgs. I truly believe that within 30 days my skin will be completely clear and virtually oil free. If it takes another 4.5 months to keep it that way for a long time, then I will be a happy guy.
[QUOTE=LowTane;3906229]No prob Nik, I found the material very interesting indeed. Thanks for sharing.

3 Mar 2009
Brand:Sotret
Weight:90Kg = 200lbs
Sex:Male
Age:48
Dosage:20mg once daily

Day26:
Blood test is done. I have an appointment day after tomorrow for my 1 month follow-up. I will ask some questions about dosage thats for sure. Well I hope this is helping anyone who wishes to monitor someone else's therapy b4 taking the plunge. I have my hair, and libido..... No bloody noses and vampire lips like some get on the higher doses. No thoughts of suicide or depression. No loss of night vision, no insomnia or nausea. Really, I can't tell I am taking this drug at all. Other than the loss of oil and the shrinking pores. Pill 26 is going down the hatch shortly. More to come..........

Peace
LowTane[/QUOTE]
Hi LowTane
Just a quick note to say how grateful I am for your posts - very informative and entertaining! Quick note about my progress...currently on day 12 of 20mg per day and things are looking good! The flushing that i experienced between days 5 and 9 have subsided and i have only a few little spots on my forehead. The pores on the rest of my face have definitely shrunk - very impressed. Minimal side effects just the usual dry lips, but nothing a good dollop of vaseline doesn't sort! Thinks that's about it. Probably going to reduce my dosage to 10mg per day when i get to the 30 day mark - see what happens there...
Cheers and keep posting!
OldLawyer LOL... Talk about hitting the nail on the head. Man I am keeping a close eye on this libido thing. I have never really had to come to terms with the possibility of losing it permanently. I still have a roving eye and my wife is wondering if I am in my second childhood. I want to test it often, which is putting me over my normal schedule. She's telling me "its fine, enough already"..... I am happy to say to all of you potential taners out there that everything still works.

5 Mar 2009
Brand:Sotret
Weight:90Kg = 200lbs
Sex:Male
Age:48
Dosage:20mg once daily

I did my bloodtest day before yesterday and I have my appointment with the Derm in a couple of hours. I am virtually blemish free and oil is no longer a problem. My back had a few blemishes, now gone. I feel relaxed and better than I have in such a long time. Life goes better without the trauma of facial acne and Rosacea. Nose is narrower and no longer throbbing with over active sebaceous glands. I will ask my Derm about the future, cumulative dose plans etc.. I have no real side effects at this point. Slightly dry nostrils, very slight and mild micro flaking of the nose. The flaking is not even noticeable unless I scrubb to hard or wash my face to long. I use cetaphil moisturizer to shave with, apply it to my nose as well and leave it on when I exit the shower. So for now, life is okay. I have taken to having a 4 oz. glass of Cab Sauv once in awhile before bed. I drink more tea than anything and I have cut soda pop almost out of my life. I did my 27th pill last night and slept like a baby. Attacked my wife this morning, just to make sure!!! All is well for now. My hair is not falling out either. More to come..... after the Doc Appt.

Best Wishes
LowTane
OldLawyer, I know how you feel. My life and my attitude have just gotten better because of this highly controversial drug. I am glad for you to be able to go out and have the nagging nusiance of Acne off your back. Right on! Good for you.....

5 Mar 2009
Brand:Sotret
Weight:90Kg = 200lbs
Sex:Male
Age:48
Dosage:20mg once daily


Day 28 or somwhere close:

I went to the Derm and he was happy with the results. He has been working with Accutane with great results for years. He told me its possible to get a complete cure from this therapy. He doesn't however have high hopes that I will get one. He said most people get remissions, but not complete cures. At least in his experience. Now all this guy does at this clinic is Accutane. Thats his primary job description. So, he is the Accutane Doc at this clinic. He shocked me by saying he would like to take the dose lower after this next month of 20mg daily. I thought he would want to go higher. He wants to see how low we can go and still get the job done. He mentioned that most people end up doing Accutane more than once. I got the feeling he thought that if you have to do Accutane more than once it would be better if it were on lower doses. I agreed! In the old days some people were put on insane dosages of 80 to 100 miiligrams daily (and still are) with the idea that higher dosages gave a better shot at a cure. Studies in multiple countries have shown that low, medium and high dosages have resulted in longterm remissions. It affects different people in different ways. My Derm mentioned that he currently had one guy on one pill a week. He didn't say how much. If he goes off that pill he immediately reverts to his pre-acne state. So, to make a long story short, this blog may truly turn into an ultra-low dose blog after next month. I got the feeling we will stop this drug for sure. If I revert to my old state I will need to go back on Antibiotics. After a period of time of an un-specified length my Doc would let me go back on the tane...... So for now I am enjoying the lack of oil and zits. Now mind you I still have scars and some holes in my nose from prior bouts with Acne. But man, do I look a lot better. I just look kinda rugged and tough, yeah, yeah thats it rugged and tough. Well somehow I got a hot wife, so I guess I can survive the look. Well thats all for now folks, pill 28 is on deck in about 6 hours. Stay strong all. Just know this, Accutane works. Low dose might be all you need.

Best Wishes
LowTane
6 Mar 2009
Brand:Sotret
Weight:90Kg = 200lbs
Sex:Male
Age:48
Dosage:20mg once daily

Day 29:
All extremely interesting OL. I started to have gastrointestinal problems from a high stress job coupled with poor diet. Diet sodas had replaced water and alcohol was a weekly event. Rosacea surfaced right on cue with the gastro problems. Many Rosaceans report the same thing, gastro first Rosacea next. Who knows, its all anecdotal....could simply be age. Well on another subject I have had some possible side effects today. A headache that lasted all day and some strangely weird wooziness and head scrambling. I had to cancel a lecture give a takehome test which tickled my collegiate captives to no end. The headache left after a good size meal and 2 asprin. The more I read about this drug the more I fear it. To many times I have read " the exact mechanism for Accutane's success is unknown". This drug has been out for 27 years. It is the number one selling drug for Roche. I have read as many as 5 million have taken this drug. It has been considered for removal from the market by the FDA. Debates have been fielded on the congressional floor over this drug. I think I am wise to be fearful. What scares me is the articles that discuss the permanence of the side effects. I for one cannot wait to get my dose lower. I have considered skip dosing, but I am afraid I may not get a long term remission if I play ping pong with the plasma levels. I don't know who reads this, but these are the things I think about.


I don't know if this helps anyone reading this blog. I can say this, my face is better than it has been in years. It feels great.....I just wonder will there be an ultimate cost. Google up side effects and lawsuits and Accutane before you even think about taking this drug.

Pill 29 on deck, maybe..........

Best Wishes
LowTane
LowTane
While there are many reports of horror stories, I take them for what they are. As an attorney, I learned long ago that if my clients are happy with my services, they tell me; if they are not, they tell everyone. Over the last 5 to 7 years of free internet access and blogs, the stories I read seem to represent a relatively small sample. Most reports show that any side effects go away after the course is complete. At 40mg per day, I have not noticed any increase in frequency of headaches. My temper seems to be a little short at times, but it is no worse than when I am on prednisone, and I learned to control it. My bottom line is that as long as the side effects are not present, I have no worry. If they appear, I will assess it then. Aspirin and cough syrup and other OTC drugs all have side effects. Reading the labels shows some can be serious and long term. As long as I give full disclosure to my doc, I will let it ride.
19 Mar 2009
Brand:Sotret
Weight:90Kg = 200lbs
Sex:Male
Age:48
Dosage:20mg every 7 days

I am not sure who is following this diatribe, but it is getting a bit thin on content. I will start posting weekly. Its getting too repetitive, all I can say is every day I am still 100% clear. I think this will get interesting again when I have terminated my low dose therapy. I leave you with this summary:

I started taking what is considered low dose Accutane for my size. This was made possible after I lobbied my Dermatologist with no less than 5 different studies on low dose Accutane from several different countries. After I dropped off the material I got a call and he set the dosage along the lines of the average low dose reported in the aforementioned studies. The first month I took 20mgs daily. I had immediate results. I had been given an antibiotic that doesn't contraindicate with Accutane in case the intial breakout was bad. He didn't want to do this at first, but it turns out I didn't need it. Accutane went to work gangbusters. With this dosage I had only some mild side effects. Slightly dampened libido, dry lower lip and an occasional mild headache. After the first month I was 100% clear. I then dropped my dosage to 20mg every 4 days. I remained clear...I then dropped it to 20mg every 7 days. I am still remaining clear at this dosage. This is where I am now.
I will continue my low dose experiment. When I have something to report I will certainly post it. Until then, I can only say you might consider low dosage if you have moderate or maybe even severe acne. You might consider low dosage if you have major oil problems. Hell you might consider low dosage if you have a hang nail......I have to say it has been a miracle for me so far. I fear the high dosage idea and will probably never ever opt for it. Doesn't mean that high dosage hasn't worked for people. It has.. I just believe that it makes permanent side effects even more possible. These are my own personal feelings, like I said, a grain of salt. I know nothing about this drug in all reality. I am just operating on my personal instincts. So, my observations only serve one purpose. They are cathartic for me. It may however help someone to hear someone else's story. Please read read read and get lots of doctor's opinions before saturating your body with this controversial miracle drug called Accutane.

I wish everyone the best.
LowTane
LowTane, Its nice to hear some positive results with low dose accutane. Im kind of in the same boat as you are. Im 22 with mild acne and really oily skin. Ive tried all the anti biotics/topicals and even ran a course of accutane at 80mg a day for 5 months back when i was 15 when i had it severe. Worked great and was clear all the way up to 07. Now i have the stubborn mild breakouts again that wont go away. I have been using the regimen sense i started breaking out again back in early 2007. It has been working ok but not enough and i really dont want to keep putting benzoyl peroxide on my face for the next 10-20 years. So i decided to go on low dose accutane at 20mg a day sense im not severe and dont want all those nasty side effects i got with the really high dose. Right now im on day 11 and so far so good. Maybe a little bit of an initial breakout but not bad and hoping it wont get worse. Im planning on running this dose for 8-10 months and then maybe cutting it back to 10 mg a day for 2-4 months or maybe even less. These studies of people running ultra low dose has me very interested as i might be a canidate if this second treatment does not allow complete remission. I will keep in touch with my progress.
Hello All

As a "high doser" I wanted to add a different perspective. I had the dosage increased last week from 40mg per day to 40mg every other day and 80mg on the other days, after 2 months of treatment. I have noticed no change and no side effects. The only real difference for me over the last 7 weeks is that I am not very hungry during the day and tend to eat more than before at night. Since I added the pills every other day, I now take one every morning and the second one at night on the required days. Before, I took them at night. I make sure I eat enough fat in the morning for max absorpsion. I acknowledge that everyone responds differntly, but for me this "normal" dose has been just fine. I assume I will be up to 80mg per day after my next visit in 3 weeks, but we shall see. I no longer consume alcohol regularly. I have imbibed twice in 7 weeks, and not to excess. I drink plenty of water. I am in a better mood most of the time, due to my improved appearance. Nonetheless, I really want the next 13 weeks to come and go so I can be done and see what happens. I remain skeptical about long term remission. I will keep you posted and wish all the low dosers the best of luck. I guess my philosophy is that if this drug is really pounding my body and my body wins, I can start the healing. My concern with low dose is that even though the pounding is less, it lasts longer. To me, it would be like getting nicked and cut until you bleed to death. So, if my body is going through the equivalent of a 5 month hangover, when the toxins are gone I will start to heal. On the otherhand, drinking every day for a few years and stopping just short of getting a hangover keeps your body from healing for a long time. Just my thoughts....
Hi all....

I am back from the Dermatologist and the blood tests are the same as always. Cholesterol and Triglycerides are normal, for me anyway. We are going to take the dosage lower. I will now skip dose the 10mg's a day to 1 capsule every other day. We talked about long term outcomes and total cumulative dosages. I would have to be on Accutane for a long time at this dosage to hit the often mentioned "total cumulative dosage" of 120mg's per kilogram of body weight. At these dosages I can see he is considering a possible maintenance dosage. He mentioned he has a guy that has been on 40mg's once a week for 7 years. Which is equal to about 5.5mg's a day. Which is around 1/15th the normal dosage of 80mg's daily for a short term therapy. So it would take 15 times as long as the normal regimen of about 4 months. So that is about 60 months, or 5 years. What does it all mean? I am not sure. I think that the more I read I find some doctors are starting to see alternative therapies as a possible course of action with Accutane. When you think about it, its possible that some individuals could get maintenance dosage levels long enough for their body to actually change on its own to an acne free state. Who knows? I can tell you this, the low dosage wouldn't even be noticeable if it weren't for the lack of zits, oil and rosacea. I am much happier at this lower dosage than I was on the 20mg's. Even though the 20mg's wasn't that bad. Still, I had some weird feelings and libido problems on 20mg's that I wasn't sure that Accutane had caused. However, on 10mg's those symptoms are gone.

Well thats about all folks, it's life changing. It's controversial and maybe even dangerous. I believe that low dosage this drug may help some people but not others. I believe some people could have problems with this drug at any dosage. I will continue to share what I can as it comes up. Read all of the studies from the links provided in multiple posts. When you goto pubmed and medscape, help me and others out here. Re-post those studies. Make sure you only post health board approved site links. Pubmed and Medscape are government run and I was told okay to link to.....

Best Wishes
LowTane
Hello all....

Just thought I would check in.... Not sure who is viewing if anyone. A quick update:

200lb
49 year old male
Sebaceous Hyperplasia
Rosacea
Acne Vulgaris
Started on 20mg Accutane daily for two months or so..
Switched to 20mg every other day for a month
Currently 10mg every other day...


All symptoms are gone!

This board has reached a statuse quo. There are no new items to report as of now other than this fact. The 10mg a day therapy seems to allow me to have normal sun exposure. I was out doing yard work on a cloudless day for 5 hours. No problems. So..continue to check back to see when the Accutane therapy ends. It will then be important to post what happens post therapy. Make sure you go back into the posts and use the Medscape and Pubmed link info to read up on different Accutane therapies taking place in different countries. This information may help sway your dermatologist into trying low dosage therapies before higher dosage therapies are employed.

Best Wishes
LowTane
Question:

If someone is on 20mg a day for 5 months (150 days), Would It be the same thing taking 40mg a day for 75 days?
Myhappy, Stoph, Exxon and OL its great to see these posts. I actually thought I was talking to myself for awhile. A couple of queries were gleaned from my reading of them.... As far as comparing one dose to the other (remember total non-professional opinion here to be taken with a bag of salt) total cummulative dose is the main theme of all Accutane prescribers..mostly. Is it the same to take different doses on different days that result in the same cummualtive dose, cummulatively yes. That was just a fun sentence to structure.... Is it the same on the body? depends on the person. Another query about front loading the drug at a higher dose for me? I really don't think my doc had that in mind. He went for the lowest dose he was comfortable with and I continued to lower it over time. We play a little game, he tells me to lower to X amount and I lower it twice as much. I goto my appointment and he is amazed. As far as he is concerned from my conversation yesterday he is controlling my oil and does not really know what is going to happen. He seems content with the idea that I can go off and back on this drug as needed. We will stop sometime and see what happens, I don't know when that will be. Probably during the summer when I am on a break. I am comfortable at these ultra low dosings and really am amazed at the results. I never wanted to take this drug in higher doses ever...and I haven't and won't. I intend to go lower yet. I am now on 10mg one day on and 2 days off......I intend to find the bottom. Call me crazy. My Doc didn't know really where he was going with this, I am guiding him really. He is studying me I think. Oil has returned to my skin on this low dose. But far less than before. I think I am at a normal level of Sebum production now. I haven't had a zit or rosacea attack for 5 months. Yeah Baby!!!!!!!

In closing:
Arm yourself with information from the links I have posted at Medscape and Pubmed. Print it out. Ask your doctor to listen to you if you don't seem to have their attention. Make it clear in your appointment how bad life is with these conditions. Maybe low dose is the answer for some and high dose for others. Good luck...........

LT
I'm on 35/150th day (20mg/day).

Blood test results continue to come back fine. I was put on Accutane with the request of other doctors who had me on meds that side effects were Acne. I always had acne, Every day I had from 2 to 5 noticeable zits on my face. Large pores, black heads, more Oily than the day before. But the meds made my breakouts more often and severe. I had big zits on my neck below with my bread grew. I'm 22 years old. I'm just so happy to be on accutane. The acne around my forehead and sideburns are no longer present, if something comes up, it goes away within a couple of days.

I take accutane with 5 fish oil gels at any meal during the day.


The noticeable effects are big red lips, they are not that dry, but it looks like a clown's lips to put in a better perspective.
If you are new to this board you should know that it is primarily about low dose Accutane for the treatment of Rosacea and Acne Vulgaris. I have posted many links to Pubmed where low dose and alternative Accutane therapy studies can be found from multiple countries. These studies have beem conducted by legitimate Dermatologists from around the world. Sadly the USA seems to be behind the curve on the low dose approach. I am currently on 10mgs 1 day on and 3 days off. I am perfectly clear and have no Rosacea flare-ups. I haven't had a single pimple in 5 months. If you create a portfoilo of studies and show them to your Derm you may get cooperation. I did. Remember that is a violation of FDA policies and is considered off label treatment. It may be that your dermatologist is not enough of a rebel to shoulder the perceived liabilities that could occur. Even though you are being administered less of the drug. What harm could that cause? I have no idea, less seems safer. So, good luck and I wish you all clear skin.

LT
Well, 5 days off accutane and nothing new to report. No increase in oil. No breakouts. I am more careful about washing my face at least 3 times a day. Some redness after very strenuous workouts. Trying to gauge if alcohol fits in to the equation, but it does not seemed to have mattered, although I haven`t drank much. I was red for a few days after a long run on Sunday. Had 3 drinks wednesday and it did not get worse....continued to clear. I will try to post once a week or so.
Thank you so much for your blog. It was of tremendous help to me. Today I began 40mg/day of Claravis. My doc would not agree to a lower dose, even tho' I requested it many times. 6 mos is my planned duration. I did visit another derm yesterday who is out of my network, who agreed that if my acne comes back after 6 mos, he'd put me on 10mg/day (possibly for a long term). I am 51, 5'6", 120lbs. Thanks to your blog, I'm armed with info, and am asking questions. I pray it works for me with minimal side effects (after 37 yrs of cystic chin acne), as it did for you. Thanks again-





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