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10 Feb 2009 Cont-
Brand:Sotret
Weight:90Kg = 200lbs
Sex:Male
Age:48
Dosage:20mg once daily
New behavior: No soda pop of any kind

I will be taking my 5th pill in a few minutes. I am still in shock that this drug shows effects in such a short time. Causes me to fear this drug even more. I will be asking my Derm to reduce the dosage for sure. He may balk, he was dragging his feet over the low dose idea. The sex drive thing put some real fear into me. I will be testing my libido regularly to detect any lapses. I hope my initial fears are in error, maybe self-fullfilling prophecy from all the negative posts on this drug. Well its show time.

:dizzy:
Best Wishes
LowTane

Declarative statement: I am not recommending this drug. I am only reporting results in the most objective manner I can muster. I do believe this drug can be dangerous. I am taking this risk of my own accord. Please read other blogs that discuss the seriousness of possible long term side effects.


Ps. Thanks for the vote of confidence BabyNyc
14 Feb 2009
Brand:Sotret
Weight:90Kg = 200lbs
Sex:Male
Age:48
Dosage:20mg once daily
New behavior:Optimism :D


Day 8 & 9:
Well its the morning of day 9 and I have taken 8 Acctuane pills for a total cumlative dose of 160 milligrams. I still take it at night before bed with a small meal. Well, I am in love with this drug, fear and all. Now, my face is never gonna be scar free without some intervention of some kind. I have had acne to long on my nose. However, Accutane is like a chemical facial. My pores are shrinking and my oil is more like a normal human at this point. I am in shock that this drug could be so rapidly effective. Blotches are already lighter than before and getting better as we go on. I can no longer even tell I am taking this drug. I have no side effects at all, not even dry lips. I have mildly insignificant micro flaking of the skin. So, inspite of the fear I am one happy camper. To Rosaceans, yesterday was flush free, and also, Acne Vulgaris seems to be in hiding. I have had a few minor pimples that have come out of the skin and been washed away. Now it should be noted that I have stopped a lot of other behavior as well. This could be helping the results along. At this point I can't really list a single problem. Now I know this could all go bad overnite so I am not going to get to euphoric and tell someone to run out and get on this drug. But I will say this, I will never take high doses of this drug ever. I made the commitment when I started that if low dose didn't work then tough luck. I have read at least 3 to 4 hundred hours on this subject. To many questions out there still even after almost 30 years of data collected on this drug. But I am hopeful that my derm may consider micro-dose long term if it will help manage my Rosacea and Acne Vulgaris. Low dose is the answer in my opinion. One more thing, the stories about diminished sex drive may be true, but for me so far that is not the case. All seems perfectly normal. Well thats all for now folks, I think I will take my (almost) oil free face out into the world for a few errands. Stay strong all............

Ps. Keep in mind that a lot more people have taken this drug than the horror stories support. If the several million people that have taken it so far all had very poor results I think this drug would be off the market for good. The reported birth defects seem to be the biggest negative factor that gets reported. I also suspect that the really high doses are causing the majority of problems where other side effects are reported. Purely an opinion from my personal research. Take it with a grain of salt, cuz I really don't know enough.

Best Wishes
LowTane :p
14 Feb 2009
Brand:Sotret
Weight:90Kg = 200lbs
Sex:Male
Age:48
Dosage:20mg once daily


Day10:
Well I suppose this log could get boring for individuals following it. To the Rosaceans reading this: I ate any an all forbidden foods and flushing seems suppressed. To the Acne crowd my acne is still in check with a few pimples here and there that are small and come out rather easily. The biggest change is the reduction in oil. That is undeniable...... with this reduction I expect comes the hopeful changes that make this drug irresistable. I can now at this juncture report that side effects are undetectable. Even the dry lips are gone. Sex drive is still intact. Eventually I will be a long termer who can report whether or not there were phantom side effects that pop up somewhere down the road long after I stop taking this controversial frightening yet wonderful drug. Hard to believe that it's a natural substance in our bodies and directly related to vitamin "A". I am feeling a lot better on this drug than the longterm antibiotics I had been taking. You can always tell you are on the antibiotics, but low dose Accutane is becoming undetectable. Well pill 9 was consumed last night and all is still okay.

Best Wishes
LowTane:wave:
Well Longhorn glad to hear from someone doing the same thing. It might be informative if you and I were to post our questions and answers to each other in this forum. That way readers (300 plus at this point) may gain from our experiences. My first question to you is what are your stats? If you could post those it would be great.

14 Feb 2009
Brand:Sotret
Weight:90Kg = 200lbs
Sex:Male
Age:48
Dosage:20mg once daily
New symptom: Itchy Face

Day 10 cont-
Well, I will make this short. I have just taken my 10th 20mg accutane pill and all is going well. No side effects of any noticable import. It seems my body has gotten use to it. My face is nicely itchy around my normal oil areas. The listed side effects: headache, nausea, bloody nose, cracking dry lips, lack of sex drive...etc.. have not occured at this dosage. My oil has been affected significantly. I have gotten a large portion of my life back in just 10 days. Pimples are showing up and emptying easily then drying out. I still may have a major outbreak coming, we shall see. I have been mildly rosy throughout, I am not sure if it really is Rosacea or some other reaction. I now do not believe I will ask for less of a dosage at my Derm appt. this month. Well I expected a horrible experience on this drug and thats not happening so far. I guess it could get worse. So far, I love it.


Best Wishes
LowTane:blob_fire
19 Feb 2009
Brand:Sotret
Weight:90Kg = 200lbs
Sex:Male
Age:48
Dosage:20mg once daily
Symptom: Dry lower lip

Well my lower lip is getting dry, slightly cracked. Not bad, I am using lip balm again. The round of acne that I have is pale and not so noticeable. I still think the ant-inflammatory of this drug is amazing. It helps to reduce redness. Zits rotate pretty fast, come and go fairly quickly. I wish I had taken pictures of my face to start with.... sorry. Quite a few views of this log have occurred by numerous individuals. I hope this helps someone who may be considering "Low Dose" Accutane. The Accutane experience has controled my oil slick of a face very rapidly. Still no major side effects and the sex drive is still intact. No depression, no headaches, nothing but the desired effects so far. I realize this could all change, so I will keep reporting. Pill #14 tonight.

Best Wishes
LowTane:cool:
OldLawyer absolutely do not stay in the background. Look how many viewers this thread has had already. Post your results so individuals who may take this option can compare more than one story. Any other individuals currently on Accutane please post as well. If you would, please list age, dosage, gender etc...

19 Feb 2009
Brand:Sotret
Weight:90Kg = 200lbs
Sex:Male
Age:48
Dosage:20mg once daily
Symptom: Dry lower lip

Day:15
Well, I am starting to sound like a broken record probably. I blotted my normally horribly oily skin one time today. Unbelievable, normally I blot 8 to 10 times a day at work. This alone is cause for celebration, I am loving this drug so far. I am on very low dosage and obtaining these results. Still no side effects other than dry lower lip. I will continue to test the sex drive on a regular basis, (somebodys gotta do it) it is in the interest of science you know.;) Well pill 15 soon......


Best Wishes
LowTane
21 Feb 2009
Brand:Sotret
Weight:90Kg = 200lbs
Sex:Male
Age:48
Dosage:20mg once daily
Symptom: Dry lower lip & Minor skin flaking on the nose.


Day 17:
Well this will be short, just the dry lower lip and the micro-flaking of the skin on the face. I know this is personal discussing the sex drive and all....but. When I was researching this drug before taking it I wanted to hear about it. Some people claim it destroyed their sex drive. Others said the symptoms persisted even after they had been off Accutane for months. So, needless to say I was scared. So far I have felt as though things were not going work properly a couple of times (yet things worked out). I am still concerned about this, it has never happened to me before. So, I am watching this very closely. I will try to report the outcome in as tasteful a way as I can. I am not sure if I have psyched my self out because of all the horror stories floating around on the web. I have been able to sucessfully accomplish the intended goal so far.....with some mental lapses. I will report any major failure if it occurs (cross your fingers)....................I hope it will not be an issue.

Pill #16 coming up.

Best Wishes
LowTane
Well Lowtane, I will post a few here and there. I am taking 40mg per day of Claravis. I have taken 7 doses so far. I take mine at night, after dinner. Days 3 through 5 resulted in some breakouts, but quite frankly no more intense than when I was on tetracycline and lotions, and they are less painful and shorter lived. No issue with sex drive yet, and besides, they make pills for that too! I continue not to drink alcohol. I drink plenty of water. I have a dry lower lip, and some redness and tightening of the face. No other side effects, except maybe that i do not seem too hungry during the day and I am starving at night. I, too, feel like I am getting my life back. My nose is less swollen and pores are smaller. I, too, wish I did this years ago, but even at age 48 I am still happy to do it now. Those who do not have these problems have no idea.
Old Lawyer, I am glad you chimed in...please do keep us updated. My wife and I were looking at my pores tonight. Honest to God I am in shock, my wife told me that I have no pores left. I had holes in my nose, I was checking into plastic surgery. I have also put alcohol on a shelf, maybe for good. I feel like drinking may have caused some of my Rosacea issues. I feel great and have lost weight by cutting out the weekly drinking. Good ta hear from ya.......:)

23 Feb 2009
Brand:Sotret
Weight:90Kg = 200lbs
Sex:Male
Age:48
Dosage:20mg once daily
Symptoms: Dry lower lip

Day 19:
Well, the pores are shocking, the oil is gone. Sex drive still seems functional, but the fear subsists. I don't know what to say, I am blown away. My Rosacea symptoms are non-existant. My attitude has just gotten better by the day. Wow, you probably think I am nuts! If I had known this option existed before, I would have stepped up to the plate a long time ago. 20mg daily has made a huge impact on my oily greasy face. It feels great to be off of antibiotics. I know I am repeating myself but I don't know what else to say. An ugly vein in my nose has all but dissappeared. I am waiting for the other shoe to drop. Acne scars are less apparent. This may be because of the lack of oil, scars and imperfections show up much better when coated with shiny oil. It also could be the tightening of the skin. Pores have closed up at an incredible rate. Its funny, now I can only think of the end of the thearapy and what will happen if I don't get the remission. Well, I should get 10 months minimum out of this, thats how long my derm has me scheduled for........ Pill #18 down the hatch.:bouncing:


Best Wished
LowTane
Thanks Blueyz..........

24 Feb 2009
Brand:Sotret
Weight:90Kg = 200lbs
Sex:Male
Age:48
Dosage:20mg once daily
Symptoms: Dry lower lip
Behavior: Cetaphil soap and moisturizer b4 bed



Day 20:
I never did use the emergency Erythromyacin my Derm gave me for the intial outbreak.
No side effects other than lower lip slightly dry.
Sex drive still functional.
Micro-flaking on nose and chin (only the areas where acne presents).
Oil reduced 95%
Rosacea symptoms = Zero!
Acne breaks and drys in 24 to 36 hours.
Pores and scarring have been affected significantly.
Confidence has improved 85 percent.
Fun factor and socialability improved beyond measure.
Pessimism diminished somewhat. (Still I do not take this drug lightly!)

Pill # 20 is on deck in one hour! :wave:

My take and speculative wishful thinking: I honestly am starting to feel that this drug at this low dose is not going to kill me. I have 100's of hours (really I do) of reading blogs and research papers on this subject. I think that the high dosage approach is where the problems can really present themselves. Even though some individuals report no problems in the long term from higher dosages. I don't think I would be comfortable on this controversial drug at the 5mg/Kg of body weight norm here in America. My hopes are at the very worse, a 5mg every other day maintenance dose (or less) in the long term if required. I am aware I could still have problems in the long term. However, this drug is 30 years old. Millions have taken it, wouldn't this be a much bigger story if everyone had long term side effects. The web shows a small group of individuals (in comparison to the number of individuals who have taken this drug) blaming this drug for every bad experience they have had post Accutane. I am not saying they are wrong, I am wondering if they are just a small percentage of a very large group. Just a thought..................

Best Wishes
LowTane

Declarative statement: I am not recommending this drug. I am only reporting results in the most objective manner I can muster. I do believe this drug can be dangerous. I am taking this risk of my own accord. Please read other blogs that discuss the seriousness of possible long and short term side effects.
Thanks for the update OldLawyer, very informative. See below for recent event:


25 Feb 2009
Brand:Sotret
Weight:90Kg = 200lbs
Sex:Male
Age:48
Dosage:20mg once daily
Symptoms: Dry lower lip
Behavior: Cetaphil soap and moisturizer b4 bed

Day 21:
I hate even reporting on this subject but I gotta. This affects both people in a relationship. I had noticed some sensation changes with this drug during intimacy in the very first days of usage. In my last encounter there was failure and I did not bother to try and finish the event. Now, you should know to put this in context that I am 48. However, this does not happen to me. I am and always have been right up till I started taking Accutane as regular as a clock, 3 to 4 times a week. What I also noticed, and maybe this is more frightening than the failure is that I didn't care. Normally, interruption of this event would cause extreme frustration. In this case it didn't bother me. You don't mind passing up a meal if your not hungry. This is significant, I am very prolific and have been my whole life. So, lets think about this. There are reports and possibly lawsuits because some people are reporting that the loss of sex drive continues even after the drug is stopped. It does make some sense, individuals taking this drug hope for remission. Meaning, after you stop the drug the benefits persist. The exact mechanism for how this drug works is not known. Oil production (the chief cause of acne) has been tied to testosterone and estrogen, which are also tied to sexual appetite. So if there is remission and longterm suppression of acne it stands to reason that suppressed sex drive could also be a result. Of course this is unprofessional layman speculation and should be taken with a grain of salt. It is to early to tell if this was just some mental event, its possible I suppose. I am very self aware though and know my body very well. I will test this out with stronger stimuli and see what the results are (I can't go into details here I am embarrassed to even be writing this as it is) after that experiment. If you surf up Accutane and sex drive, impotence etc.. you will definitely find results. I hope to give you the most accurate objective observations that I can. So, at this point I must say that I am very concerned and have some serious thinking to do. I will monitor this trend closely and discuss it with my Derm. I will continue to report to you as accurately as I can my experience on Accutane.

Note: If you are reading this, please don't jump to conclusions yet. All people respond to drugs differently. Women and men will have different attitudes about this observation. Some individuals report no problems with sexual activity while on or post Accutane.

Update: Read ahead, possible false alarm on the impotence scare.

Best Wishes
LowTane :(
25 Feb 2009
Brand:Sotret
Weight:90Kg = 200lbs
Sex:Male
Age:48
Dosage:20mg once daily

Day 21 cont-
Allrighty then...... update on the sex drive post. Now mind you my moral beliefs prohibit some things. So this is tough for me.. Further attempts to utlize my natural processes met with success. I will continue to check on this capability throughout my Accutane course and after my prescription is complete. It is possible that I have read far to much material regarding the usage of this drug. I may be psyching myself out. Intimacy is such a mental event. It should be noted that 5 million people have now taken this drug. You would think there would be more on impotence if it was prevalent. I still do believe that individuals that have reported impotence are telling the truth. Things have changed in my body. I may have psyched myself out or maybe not. To early to tell. If you are following this thread you should also remember this evidence is anecdotal at best, and the reported experiences of just one person. I am not a health care professional and have had no formal training whatsoever. So, I will just try and be honest with what I experience as it happens. I will continue to closely monitor this aspect of this therapy. I apologize if I have offended anyone, I am trying to be as discreet as possible for both women and men who may read this thread. But, hair falling out, impotence, depression and a myriad of other side effects reported by individuals who have used Accutane warrant this level of reporting. The issue is not temporary impotence, its permanent impotence that has me freaked. Some individuals have reported this effect even after stopping Accutane. I don't trust big pharma or doctors implicitly. My wife and I value our intimate relationship and I don't believe I wish to trade it for a clear face. So hang in there, I will report daily to the best of my ability any notable changes that may occur. So for now the libido outcome is still on hold.

Ps. My wife says it looks like I had a nose job, I didn't realize how swollen it was from all the excess sebaceous activity.

Keep the faith!
LowTane :p
8 Mar 2009
Brand:Sotret
Weight:90Kg = 200lbs
Sex:Male
Age:48
Dosage:20mg once daily

Day 31:
So, I skipped pill number 30. I have decided that I wish to take the minimum amount of this drug. I will be taking 1 pill every Friday night. I am 100% clear after one month on this drug. I have decided that my sex drive is slightly dampened but functional after the 600mg that was ingested in the first month. I will bump the dosage from there if needed until I arrive at the minimum maintenace level required. I had another all day headache, I skipped a dose and the headache was gone the next day. Since the Derm has mentioned a second round of this drug as a matter of doing Accutane business I am not concerned about getting the drug. I guess this is what I really wanted all along. I decided to take charge of the dosage since I am the one that will have to pay in the long run. My Derm told me he has one patient taking one pill a week which shocked me. He didn't mention it before. Multiple studies address the efficacy of low bi-weekly dosing as an effective way to maintain and acne and Rosacea free state. It will take a lot longer to reach the total cummulative dose this way, but I feel starting low and moving up is better than starting high and moving down. I have found just to many horror stories and they have started to affect me. So, if were gonna go low lets go low and prove something. If I get a remission after an even lower dose regimen and I do it with the minimum amount of this horribly controversial drug the better. If I don't I can always go back and do the the the higher dose regimen if need be.... I probably won't though. Losing my bowel to Crohn's disease (the latest lawsuit by the way, just surf it up) kinda got to me. Until I get over that I am gonna have back off on the dose levels of this drug for mental satisfaction. We all know that Accutane at doses as high as 120mg's a day have been reported. We all know that Accutane clears horrible cases of Acne and changes lives. However, you gotta read the "Ask a Patient database" and read the 393 patient reports on this drug. I have major concerns..... More to come.............

Best Wishes
LowTane
14 Mar 2009
Brand:Sotret
Weight:90Kg = 200lbs
Sex:Male
Age:48
Dosage:20mg every 4 days

Well I could see how you could get bored reading these boards. I am still marching along with the low dose Accutane. I started with 20mg a day and cleard my skin, shrunk my pores all in one month and 600mgs. I have since reduced my dosage to 20mg every 4 days. I am really tolerating the lower dose scheduling on the 4 day cycle. Sex drive definitely is different. Things work, but the miindset has been affected. I am not sure what to make of it. Oh well only time will tell. I will lower the dosage further after the next Derm appt. I am still very wary of this drug, but man, wow.....what a difference in my life it has made. Confidence, attitude and appearance have all improved. I am way happier. My pores have shrunk, my blotchines has evened out, skin is soft and taught. Just didn't realize how swollen glands and hyperplasia can change your appearance. Well, thats all.

Best Wishes
LowTane
Lowtane, you say that your sex drive has changed, i am
assuming your libido is damped..this is what happened to me
when i took low dose...now that i am considering taking it again
i 'm thinking that raising testosterone naturally(lifting weights,supplements)
might counter act the effects accutane has on our libido.
what are your thoughts?
14 Mar 2009
Brand:Sotret
Weight:90Kg = 200lbs
Sex:Male
Age:48
Dosage:20mg every 4 days

Well Chooch, I am only guessing here...but I don't think lifting weights will increase testosterone levels much. But what the hell, it couldn't hurt to try it out. Now the supplements, thats not a bad idea. Hopefully whatever you choose will not contraindicate with the Accutane. I am able to get around the damped libido effect with an adjusted mental attitude.

Shidoshi, you couldn't be more correct about helping Accutane therapy out. The modern industrial diet has provided us with many new diseases. One look at nature and we can see that proper diet and exercise keeps the animal kingdom acne free. I have cut out soda pop entirely. I have cut processed sugar to the absolute minimum. We are held captive by the shelves at Safeway. Unless you can grow your own food and hunt regularly you are basically screwed where sodium, sugar, cholesterol and fat are concerned. On your pores, mine have been giving up little hard spicules that come out when washing or just gentle rubbing. You may be shocked at just how tight your pores will get. Unless you have taken this drug before. I can't remember if it was you that posted this is your second time on Accutane.

Well good luck all, time for work unfortunately. I will keep plugging away with the lower dose regimen. I intend to go so low my Acne returns. I am flirting with the idea of longterm micro-dose. If I can stay clear on 2mg twice a week like Dr. Plewig's study suggest, I might try it. I have already noticed that 20mg every 4 days instead of every day has improved my libido.

Side effects minimal, definite slight damping of the sex drive. Extemely mild headach once in a while. Lower lip slightly dry. Thats it as far as I can tell...

Still 100% clear, with oil at an absolute minimum with just over 600mgs and only 40 days in........ unbelievable.

Best Wishes
LowTane
16 Mar 2009
Brand:Sotret
Weight:90Kg = 200lbs
Sex:Male
Age:48
Dosage:20mg every 4 days

Good to hear from ya OldLawyer, I am glad all went well at the Docs. On the internet thing, most Doctors will say the same thing with the web reading. I tend to agree to a point, but doctors are people and they are fallable. I don't believe they are perfect in their overall outlook on many things. They do however run businesses, and that in itself is an issue. You probably have run into self appointed lawyers and have the same reaction. But, the web is an incredible source of information, anecdotal yes, and produced by lay people with no formal professional training. Its all true. My case in point would be this, either your Doctor just hasn't heard of this side effect before or the multitude of individuals who report loss of sex drive after engaing in Accutane therapy are wrong. Someone has to be right, only one or the other can be true. I can find lots of people reporting this side effect. It is possibly a rare side effect in comparison to the millions who have taken Accutane. To give her credit, she probably just hasn't run into it before and believes it is not a valid side effect. I can accept that, doesn't make all the individuals reporting this side effect wrong either. It has definitely affected my libido, which is something I am very tuned into, it is slight but noticeable. As long as it isn't permanent I have no problem with this effect. It's not uncommon for many different drugs to effect libido. Albeit temporary..... Many individuals support this finding in multilple places. The web has its place and for the most part Doctors are right in suggesting that you should take web reading with a grain of salt. However, Doctors learn most of what they learn about drugs from patient feedback. Studies conducted on drugs also rely somewhat on patient feedback. The same type of feedback that is posted by every day regular people on the web. So, in the end, it is a mixed bag of nuts. Doctors in the past never had to face patients armed with so much information, some reliable and some not so reliable. My Doctor prescribed my wife Ambien and her throat swelled up and she had trouble breathing. Ambiem reported this side effect on their website as anapyhlactic shock. They suggested discontinuing the drug immediately. My Doctor who had been prescribing Ambien for several years had never heard of this side effect before. He knows now.......

I remain cautious but optimistic about this amazing controversial drug. Everyone is different and may have different side effects.

Best Wishes
LowTane
24 Mar 2009
Brand:Sotret
Weight:90Kg = 200lbs
Sex:Male
Age:48
Dosage:20mg every 2 days

Good to hear from you OL, glad all is well. I have nothing major to report, bumped my dosage back up to 20mg every two days instead of 7. This was based on reading the local dermatologists boards and gaining a consensus. Many believe the total cummulative dose is the ticket. Doesn't seem to matter how you get there, as long as you do. Mild side effects and still one hundred percent clear. Still having a small glass of Cab Sauv once in a while. Down in weight as well. Libido functional with slightly diminished drive. Well thats all folks..........

Best Wishes
LowTane
Hello!

Here is a quick summary as to the intent and direction of this thread.

49 Year Old Male
2 months of 20mg Accutane daily, reduced to 10mg daily.
Total therapy is right at 4 months.
Symptoms: Acne Vulgaris, Sebaceous Hyperplasia (massive oil) and Rosacea.
Accutane put a halt to all symptoms within the first month.
No depression, (actually the opposite) I am euphoric about the results.
Sex drive, temporary setback but settled back to normal within a month and a half.
Side effects at this point as far as I can tell are Zero.

I have posted links to multiple studies in regard to Accutane dosages. My philosophy is not my own. I got the idea for low dose therapy from the aforementioned studies. The idea is to stay on it longer than short term high dosage conventional therapies advocate. The consensus amongst the studies are that total cummulative dose is the important factor not the duration or dosage level. Not all Derms agree on this point. I am trying to prove the theory for at least one human being. I love what this drug has done for my life. Words do not do justice to the effect this has had on my job, my marriage and my mental well being.

Disclaimer: This drug can be extremely counter productive to some individuals in my humble opinion. I am a complete layman with no formal training in area pharmacology. So its obvious my opinon means little. I can only report my results.

I have an appointment on the 7th, I will report anything new. I hope that some readers will find the same satisfaction with this treatment. Print the studies linked and show your Derm. Try low dose before high dose. Most doctors won't object to this before urging you to higher dosages. I refuse the high dose therapy, I will never concede to a higher dose regimen. Thats just me...........

Best Wishes
LowTane





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