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I have been on Enbrel alone for almost 3 years with no problems. It has really been a fantastic medicine. Never have used methotrexate. All I had to do was read about the 2 gram lifetime limit and I knew it was too toxic for me to consider. As far as holistic approach, I found the omega 3 (cod liver/flax oil) combined with ZERO alcohol helped without doubt. Some people claim it does no good, but it works for me.

Drink plenty of filtered water throughout the day (2-3 qts), but don't overdo it as you can deplete sodium/minerals. Most people are chronically dehydrated and don't even know it. Or they drink tons of coffee, tea, sodas, that actually make them even more dryed out and toxic. Keep your system flushed and bad stuff doesn't accumulate and tax your body with eliminating it.

Unfortunately, once the immune system gets switched on, it usually stays on, hence the need for Enbrel. But Im hoping over time with good diet and lifestyle, it will slowly turn off and I can get off the biologics. I didnt get this overnight, so I cant expect it to be cured overnight either.

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