... I have been on Methotrexate, Plaquenil, predisone and Orencia(biologic) for several years, no serious side effects that I can identify, and they keep my RA in check. It comes down too the risks of side effects verses permanent joint damage and crippling. Due to the Plaquenil, you need eye exams every six months. I know the side effects are frightening, but foregoing treatment... (5 replies)
... however I have dreadful side effects of nusea, which is getting me down. I have started having Methotrexate in injection form, and so far this hasn't made any difference. I have an appoitment with my GP soon and will definately be asking for an alternative. ... (4 replies)
... Hi Mysteria....I spent about 7 years on Plaquenil and 5 years on MTX and just recently went off both as I see just how well another drug works. Plaquenil caused worse hair loss with me than the MTX...about half my hair fell out but I'll take bald over pain any day. But I had to stop as I developed eye problems. ... (4 replies)
... Thanks so much for the feedback! Plaquenil works really good except for the migranes. I think I'll try mtx and see if headaches go away. ... (4 replies)
... :wave: The MTX dose for autoimmune disease is about 1/1000 the dose they use in cancer patients. MTX also has a long clinical history, which makes it a trustworthy drug, they'll be no "surprise" side effects.
All immunosuppressant medications increase your risk of infection.
Still, MTX does have side effects - doesn't mean you personally have any of them, a few lucky... (4 replies)
... I was recently diagnosed with an autoimmune disease that mainly fuses my joints together, but causes severe pain and fatigue. The only problem is the Plaquenil causes severe headaches that interfer with my daily activities also. But the Dr suggested I try Methotrexate instead. ... (4 replies)
... Thanks for the response.I took the Plaquenil just before bedtime with food and so far, so good. ... (5 replies)
... I was started on Plaquenil 400mg 3 days ago. First day, no problems. Second, about 3 hours of blurred vision and felt drunk or drugged, hard to focus. Today, about 7 hours of the same. ... (5 replies)
... It looks like these messages are over a month old, but I'll add this just the same. I was diagnosed with RA in 1989. My doctor started me on Methotrexate, Prednisone, Plaquenil, iron 3 times a day and originally tylenol 3 was part of the RX, over the years and with different doctors. the tylenol was first to go about 12 years ago. and iron was replaced with folic acid. I... (36 replies)
... She just put me on Plaquenil last week, along with a week's worth of prednisone, to see how my body would react. ... (36 replies)
... I take both Plaquenil (200 mg x 3 p/day) and MTX (17.5 mg). I've been on both drugs together for almost a year. They have yet to completely control my RA (although each increase in the MTX helps) and about every 2 months, I wind up getting an 80 mg shot of depomedrol to kick a seemingly neverending flare into submission. I started Remicade and it works but my insurance... (4 replies)
... Hello, I take Plaquenil but I found that I had to take it with Prednisone for the first 2 months until it started to work. ... (4 replies)
... I am having severe RA again in my feet and ankles. Happens about at the end of every month now. Even since I've started the meds. I am on Plaquenil right now, but I am wondering how well it works since my pain has come back. I have heard some people switch over to Methotrxate if the Plaquenil doesn't work. ... (4 replies)
... I'm a nurse working with pediatric RA patients. I've given Methotrexate to children for many years. ... (36 replies)
... Hi Kerlin,
How long were you on methotrexate? I've only been on it for 1 month and the only side effects that I've encountered so far is slight dizziness and minor lip sore that goes away after a day after the medication. I take milk thistle once a day. Supposedly it prevents or helps regenerate a damage liver from different pills that one might take. I also take folic... (36 replies)
... My experience with Methotrexate was bad. I took it once a week and followed the doctor's instructions. I now need a liver transplant. ... (36 replies)
Try talking to your doctor hon - see if he can take you off one of those meds, or at least lower your dosages - and see if that helps at all.
Are you taking folic acid (for the meth side effects) and multi vitamins? do you eat something like crackers or drink milk when taking the meds?
I was tired ALL of the time before starting methotrexate - it was a side... (36 replies)
... This is my first time at this forum. I was diagnosed with RA in April. I am taking plaquenil and methotrexate. The methotrexate has been working for a month or so. But, the side effects seem to be getting worse. ... (36 replies)
... Thank you for your most informative and candid post on Methotrexate. I have had my eyes tested by an opthamologist for Plaquenil side effects and my Rheum. will take blood every six weeks for Mtx therapy. I am happy with him, he seems to be on the ball. ... (36 replies)
... Plaquenil vs Methotrexate....Be sure to know the potential side affects and what monitoring needs to take place. I thought I was told that with Plaquenil you need to monitor your eyes more carefully.... With both drugs you would need regular blood tests to monitor various blood counts as well as liver function. ... (36 replies)