... Of the specialized tests you'll probably have, one key one is ANA, a test that detects autoantibodies. However, ANA isn't specific to lupus because it may be positive in quite a few other conditions. ... (2 replies)
... Kel, for me, it took many blood labs for my doctors to trap *any* antibody. What was finally trapped: anti-Ro, which comports with the SCLE annular rashes I'd had for 8+ years, my decades of on/off symptoms, even my genes (the SCLE "subset" favors western European heritage).
Why so long for blood findings? I *think* some AB's fluctuate more than others, making some harder... (21 replies)
... Fourbirds, I often show small-ish levels of various AB's, incl. anti-ds-DNA, but my rheum isn't concerned when they test above zero; he'd only be concerned if they were truly high on the reference ranges.
Of all the labs you'be gotten back, it looks to me like the anti-microsomal AB is the one that's wildly off the charts. You said your endo prescribed a low dose of... (22 replies)
... Hi. Why not get a copy from your GP of the labs that showed high DNA? Then start a personal file, and maintain it at least while going thru the evaluation process. Then you'd know which kind* of DNA, the value + hopefully the reference range to make sense of the value. (* BTW, anti-double-stranded-DNA is redolent of systemic lupus, whereas anti-single-stranded-DNA suggests... (6 replies)
... Have you had more than one ANA and more than one anti ds DNA test done? ... (14 replies)
... Cari, personally I woudln't start Vitamin D until my drs OK it; aslo specify which form, how much & how often. I think this way because
1. You want them to see you "as is", at your natural Vit D level.
2. Taking too much Vit D is definitely dangerous. Plus, I don't know if supplementing is safe for everyone: there may be exceptions?
Hyperparathyroidism. I don't know if... (14 replies)
... My serum calcium is still normal but rising, and my urine has turned too alkaline. I haven't had a PTH test yet. ... (14 replies)
... Goldencubs, I think "ANA pattern" is assigned by the lab tech who runs the ANA test. Further, that assignment is an art, not a science, meaning is very subjective by definition. But above all, that AI's are NEVER diagnosed solely on ANA pattern, so I wouldn't think scleroderma without MANY more reasons.
ANA occurs in multiple conditions, so when positive, it's basically... (1 replies)
... A decade is way too long! I agree with the points you make, and I think all your symptoms are possible in lupus. What came to my (patient's) mind:
1. Is your doctor a rheumatotlogist? If No, you truly need one. If Yes, you need a new one, in my opinion.
2. You say you were positive "on the ANA and the blood test". Does that mean you also tested positive for one of the... (4 replies)
... endocrinologists look for it by doing a special blood test called PTH. ... (2 replies)
... Hi again. Have you seen the "sticky post" (permanent info post) containing criteria for classifying lupus? While officially called "classification criteria", these are often used to diagnose, and---IMPORTANT POINT---they are supposed to be applied cumulatively: envision checking each off in indelible ink. So when you change doctors (I did, many times), criteria you've already... (4 replies)
... As far as these test results, the only significant positive one is the ds DNA antibody, which is found in lupus. ... (3 replies)
... I have an appt. to get a second opinion for my infertility next month and I will bring all this up with him as well. Hopefully he'll agree to test me for the antiphospholipid antibody syndrome. Is this just 1 blood test? ... (6 replies)
... Lori, Where lupus is a possibility, I think elevated B.U.N. and creatine in bloodwork are signs kidneys aren't filtering properly. (I just reread your original post & realized you said those values were NOT QUITE out of range.) And urinalysis includes checks for "urine casts" and for protein in the urine, which are also signs of abnormal kidney function.
Have they... (6 replies)
... DNA with a negative ANA. Just to note, you can still have children if you have APLS, they don't all end in miscarriages. A miscarriage is just a red flag to test for this. I never understood why people who miscarry, aren't automatically tested for this. ... (6 replies)
... DNA is just one test that is specific for lupus. Although yours is a low positive, the number may change over the next few years and it should definitely be watched. ... (6 replies)
... My dr. had said all my tests were fine. The ANA screen came back negative though. Should I inquire about the Anti DS DNA? ... (6 replies)
... I remember having a blood test done a while ago when I was being worked up for something else, and the test said something about being positive for anti ds-DNA ase, and I know this is an antinuclear antibody, but does it mean that I'm going to get lupus at some time in my life? Or does it just mean that I had inflammation or something? My aunt has lupus, scleroderma, and... (1 replies)
... DNA test was done. ... (3 replies)
... Hi. Apparently anti-ds-DNA can vacillate: it can be higher just before, or at the start of, flares; and once it turns positive, it stays positive. I don't know that it's a titer test, though (sorry), you'd have to ask. Unfortunately, if the reference range on the report says >10 is positive, then >20 appears to be solidly positive, but you should confirm with someone familiar... (3 replies)