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... Good morning. This sounds very frustrating, as many of us here have likewise experienced...! Have you read the diagnostic criteria for lupus? You may find the 11 in one of the "sticky posts" above the user threads. Generally, but not always, you must meet at least 4 to sustain a diagnosis of SLE. They should be considered "permanent", i.e., envision checking each off, once... (2 replies)
Please help
Aug 7, 2016
... Hi! I was hoping maybe someone could help me here. I'm scared and waiting to hear from the rheumatologist a office to schedule. Very new to all of this. I had some bloodwork done to rule out rheumatoid arthritis and now my dr is referring me to a rheumatologist. The "asap" on the notes is alarming to me. It's difficult to find any actual number values online to see where... (8 replies)
... So sorry to read this. I believe she's in error on multiple things. issues. (1) It's possible to have lupus without ever having kidney involvement. (2) In addition to anti-ds-DNA, there are at least a dozen more autoantibodies possible in lupus. (Those reco'ed hardcovers list.) (3) ANA's that high aren't false-positives. (4) Even skin specialists can't always diagnose a malar... (11 replies)

Please help
Aug 8, 2016
... Hello & welcome. I am so NOT a doctor, so please read in that light. Although the results that ARE available (more on that in a bit) make one think of lupus, what I don't know---just as you said too---is how high your anti-dsDNA really is and what its "Crithidia titer" of 1:40 means. When I first suspected I had lupus, I thought ANY positive anti-ds-DNA was very meaningful... (8 replies)
Dsdna testing
Aug 1, 2016
... Hi, I just saw this. You may have already gotten some answers. I'm only a (dumb) patient, but I believe ANA is a very general test that can be positive in quite a few conditions, and that it's never by itself alone diagnostic of anything. For anti-ds-DNA, my lab parses results as negative, equivocal, weak positive, positive, and strong positive. I don't know what your value... (1 replies)
... I believe I posted in another thread of yours, so I won't repeat all I said before but I did want to mention asking for a CK muscle enzyme test when you feel you are having a flare of muscle weakness. There are different types of myositis and that is the best screening blood test for it. Just another piece of puzzle to fill in. (14 replies)
... Yes , it was the results by crithidia ifa testing. The only other abnormal was the high RNP and Ana of 1:160 speckled pattern over the year. I did have a skin biopsy which showed maybe indication of lupus. Like I said the rheumy just said udct even with the high RNP, but now said probably lupus. So Vee, would a 1:320 dna ds ab like really high when the normal is below 1:10?... (5 replies)
... I did see my PCP today and he said yelp looks like lupus and that my dna ds was on the upper end of mild level and with all the other testing, lupus is finally showing itself. ... (5 replies)
... Hi. Sorry but I've only seen my own anti-ds-DNA results that look different: straight numbers, no ratios, no method specified. I think your best option is to ask your rheumatologist to explain. But I strongly doubt that "some" elevation "guarantees" future kidney problems, so hang in there on that worry, OK? Also, if your serum BUN and creatine ae normal, and urinalysis... (5 replies)
... Hi. I didn't quite follow your first sentence. Were those the findings for anti-ds-DNA (anti-double-stranded DNA) on a "Crithidia immunofluorescence test"? Crithidia may be an older test with substantial pitfalls; ELISA may be more common today....? (I'm not knowledgeable on the various generations of these tests, so I hope others who know more will comment.) Was anti-RNP... (5 replies)
... Can any tell me ofmy dna da as of 1:320 is very high? Reference range is negative, 1:10 positive. The doc says probably lupus. I have high RNP of 7.8' Ana 1:160 speckled. I have at least 6 of the 11 criteria for lupus, but doc is not saying that lupus is the official dx. I am taking Plaquenil and if this does not work, wants me to try Benlysta. Not sure if it is not diffinity... (5 replies)
... Yeah, this whole thing is strange. The Rheum five years ago said: "This is why I don't like it when GP order tests." I suppose this time he/she will order a whole lot of tests. That's fine with me. I looked at the order form. It says: anti-dsdna Ab titer, serum - 255x It went to Quest Diagnostics in Baltimore, MD. Same day... *DNA (DS) AB 37 IU/ML (< or = 4) Have... (15 replies)
... Yeah, this whole thing is strange. The Rheum five years ago said: "This is why I don't like it when GP order tests." I suppose this time he/she will order a whole lot of tests. That's fine with me. I looked at the order form. It says: anti-dsdna Ab titer, serum - 255x It went to Quest Diagnostics in Baltimore, MD. Same day... *DNA (DS) AB 37 IU/ML (< or = 4) Have... (15 replies)
... Wow. I've read that Plaquenil can worsen psoriasis & understand now why your doctor & you must think a step ahead re: skin and all that pain. Let us know how it goes. Wishing you good luck! (5 replies)
... Hey Vee, missed that post about the GI issues somehow. The weight loss was intentional. I had gained about 30 lbs when I first started having stomach issues. Somehow it would feel better after I ate, so I ate cookies, crackers all the time to get it feeling ok but it never lasted long. I was also then suffering from reflux so I then had colonoscopy and endoscopy and found... (27 replies)
... Just got back on the computer and printed my lab results. Rheumy did not do a ANA, but instead it was an anti-DNA (DS)Ab Qn and that was <1. He did anti RNP, Smith (ENA)Ab, Antiscleroderma-70 antibodies, Sjorgrens anti-SS-A and anti-SS-B, Antichromatin antibodies, Jo1 Ab, Centromere B Antibodies. Like I said in the previous post, all have a range of 0-9 and mine results... (14 replies)
Ana positive
Oct 25, 2010
... Hi guys, I have a positive ana test twice now and my doctor wants me to see a rheumathologist. My test goes like this: Ana direct positive anti-dna (ds) ab qn 1 in a range of 0-9 RNP antibodies flagged as high 2.1 in a range 0.0-0.9 smith antibodies 0.2 range 0.0-0.9 antiscleroderma-70 antibodies 0.2 range 0.0-0.9 sjodren's anti-ss-a 0.2 range 0.0-0.9 sjodren's... (8 replies)
... Hi All, I'm a 26 year old female who has been experiencing achy joints and a weak feeling in my legs for the past few weeks. I went to the doctor who ordered bloodwork, which came back normal except for the following: WBC 11.0 (Normal is 4-10.5) ANA Direct Positive - There was no number provided, it just said Positive Anti-Chromatin Antibodies - 1.8 I was negative... (2 replies)
... I can't say Quest wasn't appropriate with their testing. I don't know. But there can be false negatives that occur in ANA testing. I would just have it rechecked again to be sure of the results. My guess would be that your Lupus may be in remission. Lab Corp is the lab I go to, but I have to use a different lab online in ordering the test. I can get it done for around $60... (8 replies)
... :confused: I have had bad antibodies for 3 months it took 2 months to get into see thr Dr. I dont know what's going on now. The doctor said he has never seen antibodies so high and no physical signs before.My ANA is 1483, Anti-DNA (DS)ab qn--102 RNP antibodies---500 Smith antibodies---243 Antiscleoderm-70... (5 replies)

Associated Tags: dsdna, lupus

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