... or MCTD yet always have a negative ANA test. ... (34 replies)
... Anti chromatin antibody is associated specifically with lupus and may be an early marker when other tests are negative. As with other tests, you can't make a diagnosis based on labs alone, but with meaningful symptoms as well, these labs are significant. I would review the symptoms of lupus, see how many you satisfy, and take a list with you as well as your labs to your rheum,... (9 replies)
... r places with all your other symptoms that although rare Polymyositis or Detmatomyositis should be concidered. You've already shown to have some of the positive test results for this disease. There's a lot of good info on the internet for both diseases. Good Luck. ... (34 replies)
... Ro but negative for ANA. ... (4 replies)
... I have SLE and have been taking Plaquenil for almost 2 years with ok results for the most part. When I first started on it, I was initially diagnosed with UCTD (I am ANA negative but C3 & C4 Complements were borderline low/normal), however last September the Dr. formally diagnosed as SLE. The Plaquenil was successful in bringing my C3 & C4 levels up into the normal range after... (2 replies)
... do you know if that test also checked for specific autoantibodies, as opposed to just looking for ANA then stopping cold if ANA is negative? ... (9 replies)
... Hi & welcome. I think the antibody tests are often parsed into ranges confusing to newcomers. (They were to me, anyway!) Sometimes you'll see ranges for "negative", for "low-positive", "positive", and "high-positive". I suspect that doctors generally hold off on looking for lupus if ANA is in the negative range, unless symptoms & other labs very strongly point that way.
But... (1 replies)
... I just got test results for my ANA. My doc hasn't told me if its false or not I won't know for a while. ... (1 replies)
... Hi. There's only really one presentation for lupus that I know of in which ANA stays resolutely negative, and it's exceedingly rare, especially with the improved tests now available. ... (4 replies)
... Hi & welcome. I'm only a patient, but I too believe your ANA's aren't normal & are unlikely to be false-positive at those levels. (This is true for women, as well, btw.) Did the rheum suggest follow-up monitoring or any additional tests? Did you get copies of all your labs?
In my (tiny) mind, even though you may not have met the diagnostic criteria yet for any particular... (3 replies)
... for diagnosis a positive test for a specific antibody is more important than is a negative ANA test. ... (7 replies)
... Does a negative ANA rule out SLE, as I know people test negative for ANA but still have the subset SCLE. I am confused. If anyone could clear this up, I would greatly appreciate it. ... (1 replies)
... I recently reviewed some autoimmune info and it explained that if calcium and magnesium levels were off, more cal than mag, then you could have inflammation problem. Info explained magnesium helps keep control of inflammation.
When doctors started workup on me, they were looking for protein in urine.
Info in medical books about immune inflammatory responses indicates... (29 replies)
... of negative ANA. ... (29 replies)
... I was wondering if it is possible to have any form of Lupus with out having a positive ANA test? ... (29 replies)
... I doubt that one negative ANA proves much, because blood labs by definition are really only a snapshot in time. ... (5 replies)
... three rows of extra eyelashes, and arthritis, and osteo penia. I had ana test.. ... (6 replies)
... speckled. Now ANA negative but RNP 7.8. ... (0 replies)
... It looks to me like your ANA result fell within your lab's negative range, but your dr. should confirm that, of course. ... (2 replies)
... Hi and welcome. I was told and have read that about 3 to 5% of people with systemic lupus remain ANA-negative, but test positive for anti-Ro. This subtype is called "Ro-lupus". Hopefully your doctors will test for specific autoantibodies even if your ANA stays negative---especially given your low C4, elevated ESR, etc. Hope you post more soon. Best wishes, Vee (2 replies)