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Acid Reflux / GERD Message Board

Acid Reflux / GERD Board Index

I highly recommend that try 2 doses of Nexium a day. This med at this level has helped numerous LPR patients on this board. Most people are able to metabolize Nexium a little bitter - the molecule is a little different - it's an isomer.

Many of us have had trouble with various medications. When Prilosec went OTC, I briefly switched from Nexium to Prilosec to see if it would be an adequate (and cheaper) substitute. The chronic coughing and throat clearing returned, and I had a new side effect - gobs of really thick thick thick mucous that I'd spend 2 hours coughing up upon waking. As soon as I switched back to Nexium, I returned to full recovery again within days. The Prilosec just doesn't have a good reputation among those with larygeal reflux. Remember - Prilosec was the first PPI on the market, and lost it's patent after 18 years, which is why it went OTC. Prilosec's makers introduced Nexium as it's prescription replacement - and though Nexium is rarely considered more effective than Prilosec for straight-up GERD, it's gained a very strong reputation amongst ENTS as being more helpful for LPR.
I may have to give in and try PPI's because I think my condition is getting bad enough where all of the natural things I've tried are not working enough. I've never tried Nexium because each doctor I've seen did not recommend it. Prilosec is something I tried on my own and it went fine except for the coughing so if Nexium doesn't cause that then I'd be alright. I have a very hard time sleeping sometimes and so I'm also cautious about taking any kind of medication that might affect sleep.

I'm seeing my doctor on 5/22. With the Gerd he'll probably be okay with prescribing me Nexium if want it but not sure he'll support a dose of 2x a day because LPR was not the diagnosis. I went to an ENT for a different problem by the way, mentioned my Gerd diagnosis and told him I coughed up mucous all the time. He said looking in my throat he did not see signs of Gerd or LPR!

Thanks again for the helpful insight. How long have you been taking Nexium?

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