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Acid Reflux / GERD Message Board


Acid Reflux / GERD Board Index


I've been trying to get off Aciphex since Jan this year. The rebound gets to the point of burning my esophagus that I get right back on after awhile. The last 3 months were hell.I suffered from anxiety,insomnia,stress and not to mention loads of pain because of nothing but acid rebound. Previously the longest I managed to stay off aciphex was 3 weeks. My latest attempt was the more fruitfull. I've survived 6 weeks now and I can feel my system getting back to normal.
I read about a study recently which gave me a lot of hope. They took a group of patients awaiting anti reflux surgery and measured thier gastrin hormone levels. These patients were on ppis for nearly a year prior to the study. They measured the gastrin hormone levels prior to surgery and then 4, 8, 16 and 26 weeks postoperatively. The results were startling. The acid secretion was 60% higher at 4 and 8 weeks than at 26 weeks after the operation. Thier conclusion was that Rebound acid hypersecretion lasts more than 8 weeks, but less than 26 weeks after long-term proton pump inhibition.
I think we need to give our bodies atleast 3 to 4 months to settle down so don't loose hope folks. Zee
[QUOTE=xee;4239826]I've been trying to get off Aciphex since Jan this year. The rebound gets to the point of burning my esophagus that I get right back on after awhile. The last 3 months were hell.I suffered from anxiety,insomnia,stress and not to mention loads of pain because of nothing but acid rebound. Previously the longest I managed to stay off aciphex was 3 weeks. My latest attempt was the more fruitfull. I've survived 6 weeks now and I can feel my system getting back to normal.
I read about a study recently which gave me a lot of hope. They took a group of patients awaiting anti reflux surgery and measured thier gastrin hormone levels. These patients were on ppis for nearly a year prior to the study. They measured the gastrin hormone levels prior to surgery and then 4, 8, 16 and 26 weeks postoperatively. The results were startling. The acid secretion was 60% higher at 4 and 8 weeks than at 26 weeks after the operation. Thier conclusion was that Rebound acid hypersecretion lasts more than 8 weeks, but less than 26 weeks after long-term proton pump inhibition.
I think we need to give our bodies atleast 3 to 4 months to settle down so don't loose hope folks. Zee[/QUOTE]

Xee:

I am in the same boat as you. I took Aciphex for three years and decided to get off after I discovered it had led or contributed to the development of osteopenia in both of my hips. I cut down on the dose and had my final Aciphex pill on January 24. I have been taking Zantac since then and have experienced terrible acid rebound. I think it has now settled somewhat, but still wonder three months out if I am still going through the rebound phase. I am so glad you quoted that study and would love to find the source so I could read it. I love to read posts like yours because they give me hope I too may be able to stay off the Aciphex long term and all this suffering I have gone through for the past three months has not been in vain. I created a thread in January which was recently closed titled "Getting Off PPI's and Acid Rebound." It chronicles my experience and despair through this acid rebound process.

I really appreciated your post.

Rose





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