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Acid Reflux / GERD Message Board


Acid Reflux / GERD Board Index


OK May 19th 2014 was my last Prilosec. I was starting to develop back pain twitching and itching after being on and off for 10 years. I have an appt. to see a GI doctor July 7th for an endoscopy consultation. I had one in 2006 which showed absolutely nothing wrong.

Well the reason for my post is that I was ok quitting the drug and was able to manage with a Zantac every other day or so. Yesterday though the c*** hit the fan. I started to experience horrid nausea and I popped the zantac as I had not taken one since two days prior. My question can anyone advise on the rebound side effects are of quitting PPI's as I am really freaking out right now.
The withdrawel effects of quitting PPI cold turkey can include a variety of weird symptoms due to the sudden change of chemistry in the body which may include headaches, dizziness, nausea, bone pain, sleep disturbance, bladder problems... these should soon go back to normal.

Then there is the particular symptom of rebound acid hypersecretion which is due to having taken acid suppressants. Whilst you are taking them the body is trying to fight back trying harder and harder to secrete acid, but all the time you are unaware of this whilst you are taking the drug. As soon as you stop the drug, the acid secretion goes haywire - it can take a little while before it really kicks in, as you have experienced.

The effects of hyper amounts of acid are not easily mistaken, it causes intense burning in the stomach, nausea, bloating, all sorts of stinging and tingling, and horrendous reflux. This can then cause referred pain in the back, arms and legs even.

It can be really hard, sometimes impossible to quite cold turkey which is why so many people have to wean off.

When you say the c*** hit the fan, what did you mean - what are your symptoms?



I fully sympathise with you, having had rebound I know how awful it can be. I hope you find relief soon. Don't give up, you can beat this stuff!





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