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If the pimple has a head then yuo can go ahead and pop it, afterwards disinfect with alcohol, hold a tissue to it till it stops leaking, disinfect again and then apply some antibacterial topical on it. Don't use the cortizone cream at all, it can permanently damage your skin and in the long run will give you more acne. I was prescribed cortizone cream for a burn from hot water, i read the prescription and it said that just one month of daily use would give you acne, stretch marks and other permanent skin problems. I used it just one night and through it away. Cortizone injections are very good for acne though. I had a series of them and they got rid of all my acne.

Cortizone used topically is very dangerous.

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