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I have used both of these at one time or another.. Currently I am using Taz which for me is much less irritating then Retin A.. There are two different strenghts of Taz and while I have used both, I sometimes alternate between the two of them. Keep in mind when applying either of these meds, that you need not to go overboard with them. A small amount does go a long way, and applying more will not speed up the clearing process. Another thing that you may not be aware of is that both of these can make you break out more initially. That is why sometimes I dont use the 0.01% but I use the 0.05% instead. The use of a good skin moisturizer of course is very beneficial when using both of these, and I have also found that if you use them EVERY OTHER DAY as opposed to EVERY DAY you might have less irritation.. This is not to say that this is best as everyones skin reacts differently, but this is what does work for me... I also use the AZTEC INDIAN CLAY mask on a daily basis and the combo of the two of these things have worked wonders for me. GOOD LUCK and I hope this helps you :D

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