It appears you have not yet Signed Up with our community. To Sign Up for free, please click here....



Acne Message Board


Acne Board Index
Board Index > Acne | 0-9 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z


Low Dose Accutane
Feb 6, 2009
6 Feb 2009
Hi, I have just taken my first low dose of Accutane
Brand:Sotret
Weight:90Kg=200lbs
Sex:Male
Age:48
Dosage:20mg once daily
Supplements:None

Day 1
Chronic oily skin, blotting on the hour. I have mild Rosacea and more severe Acne Vulgaris of the nose and chin. My dermatologist in the USA had no real off label experience with low and microdose accutane. I brought him multiple studies from Israel, Turkey, UK and more.... he was interested. I have a back-up of Eythromyacin, I am hoping not to use it. I have been on Doxycylcline for the last year (this is not allowed with Accutane) since being diagnosed with Rosacea. My derm will only allow for a one month antibiotic security blanket. Eythromyacin does not have contraindications with Accutane, when its gone I have to ride it out. I am Professor at a local college, needless to say it is difficult to have skin problems and have to lecture in front of crowds. I hope I am lucky and can avoid the dreaded intial outbreak so many Accutane users report.

Best Wishes
LowTane

Declarative statement: I am not recommending this drug. I am only reporting results in the most objective manner I can muster. I do believe this drug can be dangerous. I am taking this risk of my own accord. Please read other blogs that discuss the seriousness of possible long term side effects.
7 Feb 2009
Brand:Sotret
Weight:90Kg=200lbs
Sex:Male
Age:48
Dosage:20mg once daily
Supplements:None
New behavior: No alcohol or caffeine

Day 2:
I took my first Accutane 20mg pill last night at 9:00 with a bowl of oatmeal some apples and a big glass of water. Slept fine, no reported side effects. I will continue to take my dosage at night before bed. My acne is very controlled right now, I have been on daily Doxycycline for months. So, I guess so far so good.

Day 2 continued: Rosaceans I did have a flushing episode today, it was short and faded within minutes. I don't know if I can blame the accutane or not. I no longer have the security blanket of Doxycycline since it is forbidden with Accutane. I have one month of Eythromyacin but I am holding on to it for emergency situations. My Derm says thats all I get. Needless to say I was bummed out to have the flush happen. The Rosacea forums suggest even smaller doses of Accutane for Rosacea. I have both acne and Rosacea so I am torn between low dose recommendations. I also had my upper lip go slightly dry. I used lip balm and wondered if I was imagining this (I mean I have only taken one pill for Gods sake) since it is one of the most common side effects listed for Accutane users.

I just took my second pill, I have chosen to take Accutane just before bed. If there are side effects I was hoping to sleep through some of them......more to come.

Best Wishes
LowTane

Declarative statement: I am not recommending this drug. I am only reporting results in the most objective manner I can muster. I do believe this drug can be dangerous. I am taking this risk of my own accord. Please read other blogs that discuss the seriousness of possible long term side effects.
8 Feb 2009
Brand:Sotret
Weight:90Kg=200lbs
Sex:Male
Age:48
Dosage:20mg once daily
Supplements:None
New behavior: Lip Balm

Day:3
Well its official I tried caffeine again and I flushed within 3 minutes of drinking it. It appears that I no longer have the protection of Doxycyline and normal Rosacea symptoms have returned. I don't think the Accutane has caused any flushes, just normal triggers. I am for sure not imagining the dry lips. Only two pills and my lips are mildly dry. Its definitely noticeable. However, I have no headaches, no night vision problems and no detectable gastrointestinal problems. So far, I can't even really tell I have taken this drug other than the lips issue. I will take my third pill before bed tonight.

Best Wishes
LowTane

Declarative statement: I am not recommending this drug. I am only reporting results in the most objective manner I can muster. I do believe this drug can be dangerous. I am taking this risk of my own accord. Please read other blogs that discuss the seriousness of possible long term side effects.
9 Feb 2009
Brand:Sotret
Weight:90Kg=200lbs
Sex:Male
Age:48
Dosage:20mg once daily
New behavior: Zinc, Vitamin E, B and C supplements

Day 4:
Well its the morning of the 4th day. I have taken 3 20mg Sotret Acctuane pills. Slept like a baby, no sign of side effects other than the slightly dry lips. I am waiting for my acne to go crazy since I have stopped all antibiotics. I seem to be in a lull. Good! I don't want to post imaginary results but I gotta say I am waking up with less oil on my face already. Usually I am soaked. It would be hard to believe that this drug in only 3 pills could reduce my oil output already. However, if it can cause dry lips almost instantly then maybe a slight result could be possible already. I have no side effects other than the lips. No headaches, vision, nausea or pain anywhere so far. I have started to eat very healthy, low fat, grains and fruits are the route I am following. I am looking into supplements as well. I am thinking that a healthy diet and attitude might help with this therapy. I know that without antibiotics my acne should explode anytime now. We shall see.....

Best Wishes
LowTane

Declarative statement: I am not recommending this drug. I am only reporting results in the most objective manner I can muster. I do believe this drug can be dangerous. I am taking this risk of my own accord. Please read other blogs that discuss the seriousness of possible long term side effects.
10 Feb 2009
Brand:Sotret
Weight:90Kg = 200lbs
Sex:Male
Age:48
Dosage:20mg once daily
New behavior: No soda pop of any kind

Day 5:
Well I took my 4th pill last night. I know it sounds crazy but I can see changes already. I have even more fear of this drug than I had in the first place. It has to be powerful to have these effects in the short term. I definitely am waking up with less oil on my face. My first day of work was met with 50 percent less blotting with tissues. I had several events where I felt I had flushed (rosaceans pay heed) under some job stress but checking in the bathroom showed just regular looking skin. My Acne has not burst forth in the abscence antibiotics yet. Pores seem slightly smaller already. The mild lip drying is still present. I have no reported side effects with the possible exception of the lip drying and maybe one other. My libido seems to have taken several steps backwards. It should be noted that all of the results I am reporting could be due to just coincendental factors. Inside though, I really think it is this drug. I have read other Accutane logs with similar results. I am trying to be very objective, I pay attention to small details. One other thing that is definitely happening is the anti-imflammatory effect. My skin color is more even and red veined areas are looking less apparent than they have in years. I realize this is only 80 milligrams of Accutane and the diet changes could be part of this...... I don't know. It seems impossible to already be feeling the effects of this drug, but my oil ouput and skin color has shown changes. I know, I have to look in the mirror every day. I will continue to log results, I expect the suspected effects to become more apparent as time goes on. Then I can report with more confidence what I am already suspecting. I remain mildly optimistic wondering about what I am experiencing. I am thinking of asking my Derm to reduce the dosage to 10mg.

Best Wishes
LowTane

Declarative statement: I am not recommending this drug. I am only reporting results in the most objective manner I can muster. I do believe this drug can be dangerous. I am taking this risk of my own accord. Please read other blogs that discuss the seriousness of possible long term side effects.
10 Feb 2009 Cont-
Brand:Sotret
Weight:90Kg = 200lbs
Sex:Male
Age:48
Dosage:20mg once daily
New behavior: No soda pop of any kind

I will be taking my 5th pill in a few minutes. I am still in shock that this drug shows effects in such a short time. Causes me to fear this drug even more. I will be asking my Derm to reduce the dosage for sure. He may balk, he was dragging his feet over the low dose idea. The sex drive thing put some real fear into me. I will be testing my libido regularly to detect any lapses. I hope my initial fears are in error, maybe self-fullfilling prophecy from all the negative posts on this drug. Well its show time.

:dizzy:
Best Wishes
LowTane

Declarative statement: I am not recommending this drug. I am only reporting results in the most objective manner I can muster. I do believe this drug can be dangerous. I am taking this risk of my own accord. Please read other blogs that discuss the seriousness of possible long term side effects.


Ps. Thanks for the vote of confidence BabyNyc
11 Feb 2009
Brand:Sotret
Weight:90Kg = 200lbs
Sex:Male
Age:48
Dosage:20mg once daily
New behavior:None today

Day 6:
Well, I will be taking my 6th pill in a few minutes. I gotta tell ya, you probably won't believe me though. My pores which I double checked with my Wife are reduced by over 50 percent. I was blotting 10 times a day with tissues to soak up oil. I now blot 4 to 5 times a day during work. My acne was under control from a year on Doxycycline, so I didn't have much when I started Accutane. However, by now I should be breaking out gang busters with Acne Vulgaris all over my nose. Ususally my nose is throbbing from the swollen sebaceous glands. It is feeling of normal size again. It actually looks smaller. It is like a switch has been thrown and my oil glands are being told to stop. My pores are shrinking at a rapid rate. A 100mg dose (20mg once a day) of this drug has caused these reactions in only 5 days. I say it again, I am very scared of a drug that has this powerful effect in that period of time. To the rosaceans who may be vieiwing this log, I feel extreme hot flushes in the cheek but not my nose, however when I check to see how bad it is, it is insignificant. I look mildly flushed compared to how I used to look. My side effects are extremely mild to none. Slightly dry upper lip is all I have..... I have read many horror stories about this drug, I won't go into the details. So, my fear levels are high. I am happy and at the same time scared to death. I really want to take even lower doses. I have considered getting gelatin caps and a syringe and drawing out 5mg doses to put in the caps. I wished this came in pill form so I could break them into pieces. I am not sure what I am going to do yet. It almost feels as if my body needed this, it makes me wonder how it works. Its like something out of whack has been corrected. Some individuals lives are ruined by this drug. I find that it is the high dosers who report the worst problems. Low dose this drug might just be heaven sent. My job is already one hundred percent better. My wife is throwing a party this weekend and I am actually looking forward to it. Miracle or curse......we shall see.:confused:

Declarative statement: I am not recommending this drug. I am only reporting results in the most objective manner I can muster. I do believe this drug can be dangerous. I am taking this risk of my own accord. Please read other blogs that discuss the seriousness of possible long term side effects.

Best Wishes
LowTane
12 Feb 2009
Brand:Sotret
Weight:90Kg = 200lbs
Sex:Male
Age:48
Dosage:20mg once daily
New behavior:None today


Day 7:
I have had mild rosy cheeks and nose today every so often. Once for an hour or so. I do believe that the magic dose for my rosacea symptoms is probably lower. Most Rosacea forums report success with low doses. The trick is if you have both Acne Vulgaris and Rosacea to find a dose that is just right for both afflictions. Low dose studies show that 2.5 to 10 milligrams for varying sizes of people seems to work very well for Rosacea. Low dose studies for Acne seem to hover around 10 to 20 milligrams for varying sizes of people. I am going to ask for a reduction to 10 milligrams this month when I see my Derm. My skin is already looking better just because of the greasiness being minimized. Pores aren't so hideous. If this drug has this affect this soon, I wonder how fast things could go bad if I stopped taking it right now? The throbbing swollen feeling my nose has had for years is minimal now. Skin is dry and feeling smoother already. My wife has noticed the difference too. I kid you not, this is like a biological switch has been thrown. I have been waiting for the acne to explode, so far nothing. If I don't explode in another week with acne I will begin to believe that Accutane is suppressing the bacteria that causes acne somehow. Well for now I will stay on this dosage. It is so early in this trial that some readers must think I am nuts and imagining the results. I have considered that maybe I am just hitting one of those acne free windows and this is a coincedence. One thing I have noticed is the parts of my face that are not normally oily are very dry and smooth. My whole face feels tight. I am using Cetaphil on my cheeks. If my Derm won't go for a reduction in dosage I may move to skip dosing and take 20mg every other day. Well thats all for now, gotta go take pill number 7.
:wave:

Ps. I mentioned a Libido scare a few posts ago, well it checks out fine. (Well, for a 48 year old anyways!) ;)

Best Wishes
LowTane
14 Feb 2009
Brand:Sotret
Weight:90Kg = 200lbs
Sex:Male
Age:48
Dosage:20mg once daily
New behavior:Optimism :D


Day 8 & 9:
Well its the morning of day 9 and I have taken 8 Acctuane pills for a total cumlative dose of 160 milligrams. I still take it at night before bed with a small meal. Well, I am in love with this drug, fear and all. Now, my face is never gonna be scar free without some intervention of some kind. I have had acne to long on my nose. However, Accutane is like a chemical facial. My pores are shrinking and my oil is more like a normal human at this point. I am in shock that this drug could be so rapidly effective. Blotches are already lighter than before and getting better as we go on. I can no longer even tell I am taking this drug. I have no side effects at all, not even dry lips. I have mildly insignificant micro flaking of the skin. So, inspite of the fear I am one happy camper. To Rosaceans, yesterday was flush free, and also, Acne Vulgaris seems to be in hiding. I have had a few minor pimples that have come out of the skin and been washed away. Now it should be noted that I have stopped a lot of other behavior as well. This could be helping the results along. At this point I can't really list a single problem. Now I know this could all go bad overnite so I am not going to get to euphoric and tell someone to run out and get on this drug. But I will say this, I will never take high doses of this drug ever. I made the commitment when I started that if low dose didn't work then tough luck. I have read at least 3 to 4 hundred hours on this subject. To many questions out there still even after almost 30 years of data collected on this drug. But I am hopeful that my derm may consider micro-dose long term if it will help manage my Rosacea and Acne Vulgaris. Low dose is the answer in my opinion. One more thing, the stories about diminished sex drive may be true, but for me so far that is not the case. All seems perfectly normal. Well thats all for now folks, I think I will take my (almost) oil free face out into the world for a few errands. Stay strong all............

Ps. Keep in mind that a lot more people have taken this drug than the horror stories support. If the several million people that have taken it so far all had very poor results I think this drug would be off the market for good. The reported birth defects seem to be the biggest negative factor that gets reported. I also suspect that the really high doses are causing the majority of problems where other side effects are reported. Purely an opinion from my personal research. Take it with a grain of salt, cuz I really don't know enough.

Best Wishes
LowTane :p
Well Longhorn glad to hear from someone doing the same thing. It might be informative if you and I were to post our questions and answers to each other in this forum. That way readers (300 plus at this point) may gain from our experiences. My first question to you is what are your stats? If you could post those it would be great.

14 Feb 2009
Brand:Sotret
Weight:90Kg = 200lbs
Sex:Male
Age:48
Dosage:20mg once daily
New symptom: Itchy Face

Day 10 cont-
Well, I will make this short. I have just taken my 10th 20mg accutane pill and all is going well. No side effects of any noticable import. It seems my body has gotten use to it. My face is nicely itchy around my normal oil areas. The listed side effects: headache, nausea, bloody nose, cracking dry lips, lack of sex drive...etc.. have not occured at this dosage. My oil has been affected significantly. I have gotten a large portion of my life back in just 10 days. Pimples are showing up and emptying easily then drying out. I still may have a major outbreak coming, we shall see. I have been mildly rosy throughout, I am not sure if it really is Rosacea or some other reaction. I now do not believe I will ask for less of a dosage at my Derm appt. this month. Well I expected a horrible experience on this drug and thats not happening so far. I guess it could get worse. So far, I love it.


Best Wishes
LowTane:blob_fire
16 Feb 2009
Brand:Sotret
Weight:90Kg = 200lbs
Sex:Male
Age:48
Dosage:20mg once daily
New symptom: Sunburn easily

Day 11:
I went to play golf today and got red within one hour. I remember reading that Accutane makes you sensitive to sunshine (UV). Definitely sensitive, turned red quickly. Could be a combo of Rosacea and sunburn. Will wear sunblock from now on. No other side effects present. None.

Best Wishes
LowTane :p
17 Feb 2009
Brand:Sotret
Weight:90Kg = 200lbs
Sex:Male
Age:48
Dosage:20mg once daily

Day 12:
Well I took pill #11 last night. I am now getting acne on my chin and nose. I suspect the cessation of Doxycycline has allowed the bacterial populations to come back. Since Accutane is not an antibiotic I am bound to catch a few. They hurt...... Accutane cuts sebaceous activity and thereby reducing the food source for the bacteria that makes acne possible. It's hard to believe I am almost 50 and I am going through the trials and tribulations of a teenager. I will continue my regimen and play this game to the end. I hope this is the initial dreaded breakout I read about in other forums. Right now my oil is extemely reduced but not eliminated. Not on this dose and not at this time. I will continue to report changes in physiology as I experience them. I hope this helps someone out there who may be contemplating Accutane. I have calculated that the total cummulative dose of Accutane of 120mg per kg of body weight for best permanent remission opportunity would not occur for 540 days on this dosage. Something to talk to the Derm about.

Day 12: Cont-
Its time for pill number 12 here shortly. It should be noted that absorbtion can be increased by taking Accutane with a fatty meal. Hmmmmm...you can somewhat adust your dosage just by food selection. Well, the acne doesn't hurt as much as it did earlier. Its not very red either. Seems this drug is a wonderful anti-inflammatory substance. Face is still mildly itchy, lips are no longer dry at all. My face is better in just under two weeks on this drug than it has been in a long time. Well thats all for today. Pill #12 is on deck.

Best



Best Wishes
LowTane
18 Feb 2009
Brand:Sotret
Weight:90Kg = 200lbs
Sex:Male
Age:48
Dosage:20mg once daily

Day 13:
I gotta say, that Accutane changes the normal process for a zit. I was already for a long drawn out process for my new acne. It started very painful as usual, but.... my zits are drying up quick. Its as if they are drying from the inside out. Pain came and went. The normal expected redness and swelling is very mild in comparison to past acne events. Wow, I am loving this drug. Pores that I expected would need surgery are much, much reduced in size and appearance. Oil is still very well controlled. I have no side effects whatsoever. My attitude is improved 100%. After reading all the horror stories online I was braced for the worst. I might as well be taking a vitamin pill. I am thinking that the Europeans have it right. We are giving much to high of dosages in the United States of this powerful drug. Pill #13 goes down tonight.

Day 13: cont-
I just took pill #13 a few moments ago. I have two zits on the chin and 3 on the nose. They are not that red though. It really is a lot easier to deal with the zits on this drug. I hope this does not last for weeks. It would be nice to get past the intial breakout. To the Rosaceans. No flushing at all, no hot skin...nothing. It seems this drug does control Rosacea. The downside is I have heard it doesn't cure it like it can Acne. When all is said and done the next hurdle may be getting a Derm to commit to long term Microdose Tane. Well, good nite.


Best Wishes
LowTane:D
19 Feb 2009
Brand:Sotret
Weight:90Kg = 200lbs
Sex:Male
Age:48
Dosage:20mg once daily
Symptom: Dry lower lip

Well my lower lip is getting dry, slightly cracked. Not bad, I am using lip balm again. The round of acne that I have is pale and not so noticeable. I still think the ant-inflammatory of this drug is amazing. It helps to reduce redness. Zits rotate pretty fast, come and go fairly quickly. I wish I had taken pictures of my face to start with.... sorry. Quite a few views of this log have occurred by numerous individuals. I hope this helps someone who may be considering "Low Dose" Accutane. The Accutane experience has controled my oil slick of a face very rapidly. Still no major side effects and the sex drive is still intact. No depression, no headaches, nothing but the desired effects so far. I realize this could all change, so I will keep reporting. Pill #14 tonight.

Best Wishes
LowTane:cool:
I started on Monday 2/16. I am 48, male,190 lbs and am on 40mg/day. My systoms are similar to your except I was on tetracycline for 11 years (absurd, I know) and everything else that did not work. My breakouts were usually not bad, mostly on the nose and trunk. My face started to get really read last October and it took me 4 months to get a derm appt. Since nothing else worked, including prescription creams, they said this was the best option.

I decided to quit drinking while I am on it...will make friday nights rather dull, but I like my liver.

The first day I had some mild headaches. The second day I broke out a little, but I`m not sure if it is from the accutane or the fact that I stopped using everything else. Today I was a little more broken out but they went as quickly as they came, which was strange. My eyes get very dry about an hour after I take it (with dinner) and that lasts for an hour or 2. My skin is less oily, for now. I sleep like a rock.

I was told to drink a lot of water and exercise and eat well.

My 19 year old daughter just finished up. She was never that bad but nothing got rid of her mild acne so she tried it and has flawless skin.

Good luck. Keep in touch.



[QUOTE=LowTane;3877069]6 Feb 2009
Hi, I have just taken my first low dose of Accutane
Brand:Sotret
Weight:90Kg=200lbs
Sex:Male
Age:48
Dosage:20mg once daily
Supplements:None

Day 1
Chronic oily skin, blotting on the hour. I have mild Rosacea and more severe Acne Vulgaris of the nose and chin. My dermatologist in the USA had no real off label experience with low and microdose accutane. I brought him multiple studies from Israel, Turkey, UK and more.... he was interested. I have a back-up of Eythromyacin, I am hoping not to use it. I have been on Doxycylcline for the last year (this is not allowed with Accutane) since being diagnosed with Rosacea. My derm will only allow for a one month antibiotic security blanket. Eythromyacin does not have contraindications with Accutane, when its gone I have to ride it out. I am Professor at a local college, needless to say it is difficult to have skin problems and have to lecture in front of crowds. I hope I am lucky and can avoid the dreaded intial outbreak so many Accutane users report.

Best Wishes
LowTane

Declarative statement: I am not recommending this drug. I am only reporting results in the most objective manner I can muster. I do belive this drug can be dangerous. I am taking this risk of my own accord. Please read other blogs that discuss the seriousness of possible long term side effects.[/QUOTE]
OldLawyer absolutely do not stay in the background. Look how many viewers this thread has had already. Post your results so individuals who may take this option can compare more than one story. Any other individuals currently on Accutane please post as well. If you would, please list age, dosage, gender etc...

19 Feb 2009
Brand:Sotret
Weight:90Kg = 200lbs
Sex:Male
Age:48
Dosage:20mg once daily
Symptom: Dry lower lip

Day:15
Well, I am starting to sound like a broken record probably. I blotted my normally horribly oily skin one time today. Unbelievable, normally I blot 8 to 10 times a day at work. This alone is cause for celebration, I am loving this drug so far. I am on very low dosage and obtaining these results. Still no side effects other than dry lower lip. I will continue to test the sex drive on a regular basis, (somebodys gotta do it) it is in the interest of science you know.;) Well pill 15 soon......


Best Wishes
LowTane
21 Feb 2009
Brand:Sotret
Weight:90Kg = 200lbs
Sex:Male
Age:48
Dosage:20mg once daily
Symptom: Dry lower lip & Minor skin flaking on the nose.


Day 17:
Well this will be short, just the dry lower lip and the micro-flaking of the skin on the face. I know this is personal discussing the sex drive and all....but. When I was researching this drug before taking it I wanted to hear about it. Some people claim it destroyed their sex drive. Others said the symptoms persisted even after they had been off Accutane for months. So, needless to say I was scared. So far I have felt as though things were not going work properly a couple of times (yet things worked out). I am still concerned about this, it has never happened to me before. So, I am watching this very closely. I will try to report the outcome in as tasteful a way as I can. I am not sure if I have psyched my self out because of all the horror stories floating around on the web. I have been able to sucessfully accomplish the intended goal so far.....with some mental lapses. I will report any major failure if it occurs (cross your fingers)....................I hope it will not be an issue.

Pill #16 coming up.

Best Wishes
LowTane
22 Feb 2009
Brand:Sotret
Weight:90Kg = 200lbs
Sex:Male
Age:48
Dosage:20mg once daily
Symptom: Dry lower lip & Minor skin flaking on the nose.


Day 17: Well this report will be a summary of events upto this time. I have experienced no significant side effects from this low dosage of Accutane. I am taking the Sotret brand. My lower lip is just barely dry. Every now and then I have a little piece of skin on my lip get dry enough to peel off with my teeth. This is rare, now this is significant. If you haven't seen what "high dosers" go through you need to go surf and read. Then again, I may not get the successful remission that high dosers may get. Now for the good part. My life has been so positively affected that I am shocked. My attitude, my willingness to participate in life. My students have noticed the difference, I am having fun teaching again. My personal space when talking to people has gotten to a normal distance again. I am not blotting during the day more than once or twice. I can touch my nose and my fingers don't feel greasy. My zits are coming and going at a rapid rate. My red blotchy appearance is showing a more even normal colored skin tone. Pores I thought were going to take plastic surgery have shrunk by 65%. My nose dosen't feel swollen anymore. My rosacea symptoms are non-existent. Veins in my nose have dissappeared. What can I say, I am hooked on Acctuane. My quality of life has already improved by 80% in just a little over two weeks on this miraculous drug. I can't tell you how this makes me feel, what an amazing experience it has been already. So, there.... thats how I feel today. I wished to God I had tried this drug a lot earlier, before I had so much scarring. Oh well... maybe laser will finish this journey off it I get a good remission. Well, folks...I recommend a low dose experience, even lower than mine. Possibly microdose will be the way of the future. 2.5 milligrams total daily. Like a supplement, who knows. Well, pill #17 is on deck. I will take it with milk to increase the absorbtion. It is fat soluable..............:p


Best Wishes
LowTane
Old Lawyer, I am glad you chimed in...please do keep us updated. My wife and I were looking at my pores tonight. Honest to God I am in shock, my wife told me that I have no pores left. I had holes in my nose, I was checking into plastic surgery. I have also put alcohol on a shelf, maybe for good. I feel like drinking may have caused some of my Rosacea issues. I feel great and have lost weight by cutting out the weekly drinking. Good ta hear from ya.......:)

23 Feb 2009
Brand:Sotret
Weight:90Kg = 200lbs
Sex:Male
Age:48
Dosage:20mg once daily
Symptoms: Dry lower lip

Day 19:
Well, the pores are shocking, the oil is gone. Sex drive still seems functional, but the fear subsists. I don't know what to say, I am blown away. My Rosacea symptoms are non-existant. My attitude has just gotten better by the day. Wow, you probably think I am nuts! If I had known this option existed before, I would have stepped up to the plate a long time ago. 20mg daily has made a huge impact on my oily greasy face. It feels great to be off of antibiotics. I know I am repeating myself but I don't know what else to say. An ugly vein in my nose has all but dissappeared. I am waiting for the other shoe to drop. Acne scars are less apparent. This may be because of the lack of oil, scars and imperfections show up much better when coated with shiny oil. It also could be the tightening of the skin. Pores have closed up at an incredible rate. Its funny, now I can only think of the end of the thearapy and what will happen if I don't get the remission. Well, I should get 10 months minimum out of this, thats how long my derm has me scheduled for........ Pill #18 down the hatch.:bouncing:


Best Wished
LowTane
Thanks Blueyz..........

24 Feb 2009
Brand:Sotret
Weight:90Kg = 200lbs
Sex:Male
Age:48
Dosage:20mg once daily
Symptoms: Dry lower lip
Behavior: Cetaphil soap and moisturizer b4 bed



Day 20:
I never did use the emergency Erythromyacin my Derm gave me for the intial outbreak.
No side effects other than lower lip slightly dry.
Sex drive still functional.
Micro-flaking on nose and chin (only the areas where acne presents).
Oil reduced 95%
Rosacea symptoms = Zero!
Acne breaks and drys in 24 to 36 hours.
Pores and scarring have been affected significantly.
Confidence has improved 85 percent.
Fun factor and socialability improved beyond measure.
Pessimism diminished somewhat. (Still I do not take this drug lightly!)

Pill # 20 is on deck in one hour! :wave:

My take and speculative wishful thinking: I honestly am starting to feel that this drug at this low dose is not going to kill me. I have 100's of hours (really I do) of reading blogs and research papers on this subject. I think that the high dosage approach is where the problems can really present themselves. Even though some individuals report no problems in the long term from higher dosages. I don't think I would be comfortable on this controversial drug at the 5mg/Kg of body weight norm here in America. My hopes are at the very worse, a 5mg every other day maintenance dose (or less) in the long term if required. I am aware I could still have problems in the long term. However, this drug is 30 years old. Millions have taken it, wouldn't this be a much bigger story if everyone had long term side effects. The web shows a small group of individuals (in comparison to the number of individuals who have taken this drug) blaming this drug for every bad experience they have had post Accutane. I am not saying they are wrong, I am wondering if they are just a small percentage of a very large group. Just a thought..................

Best Wishes
LowTane

Declarative statement: I am not recommending this drug. I am only reporting results in the most objective manner I can muster. I do believe this drug can be dangerous. I am taking this risk of my own accord. Please read other blogs that discuss the seriousness of possible long and short term side effects.
Thanks for the update OldLawyer, very informative. See below for recent event:


25 Feb 2009
Brand:Sotret
Weight:90Kg = 200lbs
Sex:Male
Age:48
Dosage:20mg once daily
Symptoms: Dry lower lip
Behavior: Cetaphil soap and moisturizer b4 bed

Day 21:
I hate even reporting on this subject but I gotta. This affects both people in a relationship. I had noticed some sensation changes with this drug during intimacy in the very first days of usage. In my last encounter there was failure and I did not bother to try and finish the event. Now, you should know to put this in context that I am 48. However, this does not happen to me. I am and always have been right up till I started taking Accutane as regular as a clock, 3 to 4 times a week. What I also noticed, and maybe this is more frightening than the failure is that I didn't care. Normally, interruption of this event would cause extreme frustration. In this case it didn't bother me. You don't mind passing up a meal if your not hungry. This is significant, I am very prolific and have been my whole life. So, lets think about this. There are reports and possibly lawsuits because some people are reporting that the loss of sex drive continues even after the drug is stopped. It does make some sense, individuals taking this drug hope for remission. Meaning, after you stop the drug the benefits persist. The exact mechanism for how this drug works is not known. Oil production (the chief cause of acne) has been tied to testosterone and estrogen, which are also tied to sexual appetite. So if there is remission and longterm suppression of acne it stands to reason that suppressed sex drive could also be a result. Of course this is unprofessional layman speculation and should be taken with a grain of salt. It is to early to tell if this was just some mental event, its possible I suppose. I am very self aware though and know my body very well. I will test this out with stronger stimuli and see what the results are (I can't go into details here I am embarrassed to even be writing this as it is) after that experiment. If you surf up Accutane and sex drive, impotence etc.. you will definitely find results. I hope to give you the most accurate objective observations that I can. So, at this point I must say that I am very concerned and have some serious thinking to do. I will monitor this trend closely and discuss it with my Derm. I will continue to report to you as accurately as I can my experience on Accutane.

Note: If you are reading this, please don't jump to conclusions yet. All people respond to drugs differently. Women and men will have different attitudes about this observation. Some individuals report no problems with sexual activity while on or post Accutane.

Update: Read ahead, possible false alarm on the impotence scare.

Best Wishes
LowTane :(
25 Feb 2009
Brand:Sotret
Weight:90Kg = 200lbs
Sex:Male
Age:48
Dosage:20mg once daily

Day 21 cont-
Allrighty then...... update on the sex drive post. Now mind you my moral beliefs prohibit some things. So this is tough for me.. Further attempts to utlize my natural processes met with success. I will continue to check on this capability throughout my Accutane course and after my prescription is complete. It is possible that I have read far to much material regarding the usage of this drug. I may be psyching myself out. Intimacy is such a mental event. It should be noted that 5 million people have now taken this drug. You would think there would be more on impotence if it was prevalent. I still do believe that individuals that have reported impotence are telling the truth. Things have changed in my body. I may have psyched myself out or maybe not. To early to tell. If you are following this thread you should also remember this evidence is anecdotal at best, and the reported experiences of just one person. I am not a health care professional and have had no formal training whatsoever. So, I will just try and be honest with what I experience as it happens. I will continue to closely monitor this aspect of this therapy. I apologize if I have offended anyone, I am trying to be as discreet as possible for both women and men who may read this thread. But, hair falling out, impotence, depression and a myriad of other side effects reported by individuals who have used Accutane warrant this level of reporting. The issue is not temporary impotence, its permanent impotence that has me freaked. Some individuals have reported this effect even after stopping Accutane. I don't trust big pharma or doctors implicitly. My wife and I value our intimate relationship and I don't believe I wish to trade it for a clear face. So hang in there, I will report daily to the best of my ability any notable changes that may occur. So for now the libido outcome is still on hold.

Ps. My wife says it looks like I had a nose job, I didn't realize how swollen it was from all the excess sebaceous activity.

Keep the faith!
LowTane :p
25 Feb 2009
Brand:Sotret
Weight:90Kg = 200lbs
Sex:Male
Age:48
Dosage:20mg once daily
Symptoms:Lower lip is a lot dryer than before. Cracking a little now.

Day 21 cont- cont-
Well pill # 20 is on deck pretty soon here. I thought about the implications of the possibility of permanently losing my libido all day. I had read posts where it had been reported. So, I am kinda freaked. Things are still working so far. I will probably quit this drug and back track if I start to have numerous negative events. I will ask my Derm this month about what he has heard. I don't expect much feedback on this subject. Roche does not list this as a side effect and most people are squeamish about discussing libido. I guess I had two big fears going into this, losing my hair and my libido. My research cemented these two as my biggest fears. On the other side of the coin, damn..... I am loving my face. What a great break from the oily mess I had. I feel human again. I would like to remind anyone following this thread that I am type "A" all the way and have a tendancy to over analyze. This has its plusses and its minuses. I will observe the smallest detail and try to figure it out. If I finish this course of Accutane I will continue to report so that individuals may benefit from my experience. If side effects surface after therapy I will post the experience. I hope this helps someone out there. I feel like a human guinea pig. Wow! My face is great. I am blown away and yes still scared out of my wits at the same time. I would like to ask anyone else out there to post any changes in sexual behavior they may have experienced on this drug. Good or bad..........


Best Wishes
LowTane :cool:
26 Feb 2009
Brand:Sotret
Weight:90Kg = 200lbs
Sex:Male
Age:48
Dosage:20mg once daily
Symptoms:Lower lip is a lot dryer than before. Cracking a little now.

Day 22:

Applied carmex to the lower lip and it worked like a charm. Face is now almost 100% clear. Blotches are fading and oil is gone. I am happy to say that all biological processes are working just fine. My blood test is coming up quick I am hoping cholesterol and triglycerides are acceptable. Can't forget liver enzymes too...... I am thinking that maybe the libido is going to be okay. I think that I have never been so concerned about a medication before and it may be causing some over reaction to normal events. We shall see. All of the horror stories on the web have impacted my psyche. I need to keep this in perspective. 5 million users, less than a hundred examples of web posts discussing permanently lost libidos. I hope I haven't freaked out any potential Accutane users at this point. If I did I apologize, if things do fail in the future I will try to alert blog readers to the problems in a sober manner. I will closely scrutinize all aspects of my body during the entire Accutane regimen. I will keep you posted.

Best Wishes
LowTane
Well OldLawyer, thanks for the comments. I am jumpier than a longtailed cat in a room full of rocking chairs over this medication. I mean its just a fact, Accutane is controversial, period. I gotta say though, wow! What an amazing job it has done in healing my tortured schnoz and chin. I still blot out of habit sometimes, minimal oil is present. My nose is very narrow now. Still healing a few places and blotches are dimming. Luvvin it..........!!!!


26 Feb 2009
Brand:Sotret
Weight:90Kg = 200lbs
Sex:Male
Age:48
Dosage:20mg once daily
Symptoms:Lower lip is a lot dryer than before. Cracking a little now.

Day 21:

Well pill 21 is on deck, I may have messed up the count in prior posts. I am done freaking out for now over my private intimate life. For now..... Face and confidence are on a parallel path. Life is better than it has been in quite sometime. Dry lips are easily handled. No other side effects can be detected. Sleep just fine, no headaches or body aches like some individuals report. No night blindess whatsoever. I am really happy with the results. If there is no final potential price to pay for this amazing miracle drug I will be extemely greatful. I see people on the streets and in the classroom that have oily skin and blotchy painful looking acne and I want to say something to these people. Like "Do you realize you could possibly be completely clear of acne in less than a month?" Then I think about the controversy surrounding this drug and I keep my mouth shut. I can't recommend this drug because it scares the crap outta me............. I can report what I experience though and hope individuals that decide to use this drug based on what others say still realize it could turnout bad for them, regardless of the success others may have. Thats the bottom line..........

Best Wishes
LowTane
Likewise Nikki, I wish you the best of luck. Thanks a ton for bringing up therapy for Acne I had never heard of..........
1 Mar 2009
Brand:Sotret
Weight:90Kg = 200lbs
Sex:Male
Age:48
Dosage:20mg once daily

Day 24:
Pill 24 on deck, not a ton to report other than a few zits arrived and exited fairly quickly. Oil is still highly contolled, no side effects I can perceive easily. Little flaking here and there, lower lip etc.. I am definitely thinking already about the end of this therapy. I feel like the low dose over the longterm is easier on the body than the higher doses. Its hard to tell at this point that I am taking a drug at all. Rosacea with slight flushing here an there, but no papules or bumps anywhere. Pores have shrunk a lot, it will be interesting to see if they can even shrink more. Libido, check.. all good. I will continue to report as long as I can find something to say of substance. I feel like this is just a repeat at this point. So, I have taken to try and post something to read that may be meaningful. Well, its time.....

BestWishes
LowTane
Good to hear from ya OldLawyer....Thanks for the input. Your musings are like mine. Even at a conventional dosage of .5mg/kg body weight ratio I wouldn't reach the vague pseudo cure dosage of 10,800 milligrams for around 250 days at 45mg. At 20mg we are talking 540 days or 18 months. So even my Derm has me scheduled for less than the recommended cumulative dosage. Unless he decides to keep going after we get to the 10 months he has me scheduled for.........Questions I will pose for him when I see him. Blood test is tomorrow.


2 Mar 2009
Brand:Sotret
Weight:90Kg = 200lbs
Sex:Male
Age:48
Dosage:20mg once daily

Well pill #25 is up and coming shortly. We got one medium doser and one low doser same age and weight on this board. We are both having amazing results with no real side effects. What have we learned. Well, both dosages are working. What will happen when we end our therapies? I don't know. Only one way to find out, we gotta finish this thing. I am in the same condition, none to moderate oil, libido works, and minimal skin flaking. Thats it for now. More to report after my appointment this week.

Best Wishes
LowTane
OldLawyer LOL... Talk about hitting the nail on the head. Man I am keeping a close eye on this libido thing. I have never really had to come to terms with the possibility of losing it permanently. I still have a roving eye and my wife is wondering if I am in my second childhood. I want to test it often, which is putting me over my normal schedule. She's telling me "its fine, enough already"..... I am happy to say to all of you potential taners out there that everything still works.

5 Mar 2009
Brand:Sotret
Weight:90Kg = 200lbs
Sex:Male
Age:48
Dosage:20mg once daily

I did my bloodtest day before yesterday and I have my appointment with the Derm in a couple of hours. I am virtually blemish free and oil is no longer a problem. My back had a few blemishes, now gone. I feel relaxed and better than I have in such a long time. Life goes better without the trauma of facial acne and Rosacea. Nose is narrower and no longer throbbing with over active sebaceous glands. I will ask my Derm about the future, cumulative dose plans etc.. I have no real side effects at this point. Slightly dry nostrils, very slight and mild micro flaking of the nose. The flaking is not even noticeable unless I scrubb to hard or wash my face to long. I use cetaphil moisturizer to shave with, apply it to my nose as well and leave it on when I exit the shower. So for now, life is okay. I have taken to having a 4 oz. glass of Cab Sauv once in awhile before bed. I drink more tea than anything and I have cut soda pop almost out of my life. I did my 27th pill last night and slept like a baby. Attacked my wife this morning, just to make sure!!! All is well for now. My hair is not falling out either. More to come..... after the Doc Appt.

Best Wishes
LowTane
OldLawyer, I know how you feel. My life and my attitude have just gotten better because of this highly controversial drug. I am glad for you to be able to go out and have the nagging nusiance of Acne off your back. Right on! Good for you.....

5 Mar 2009
Brand:Sotret
Weight:90Kg = 200lbs
Sex:Male
Age:48
Dosage:20mg once daily


Day 28 or somwhere close:

I went to the Derm and he was happy with the results. He has been working with Accutane with great results for years. He told me its possible to get a complete cure from this therapy. He doesn't however have high hopes that I will get one. He said most people get remissions, but not complete cures. At least in his experience. Now all this guy does at this clinic is Accutane. Thats his primary job description. So, he is the Accutane Doc at this clinic. He shocked me by saying he would like to take the dose lower after this next month of 20mg daily. I thought he would want to go higher. He wants to see how low we can go and still get the job done. He mentioned that most people end up doing Accutane more than once. I got the feeling he thought that if you have to do Accutane more than once it would be better if it were on lower doses. I agreed! In the old days some people were put on insane dosages of 80 to 100 miiligrams daily (and still are) with the idea that higher dosages gave a better shot at a cure. Studies in multiple countries have shown that low, medium and high dosages have resulted in longterm remissions. It affects different people in different ways. My Derm mentioned that he currently had one guy on one pill a week. He didn't say how much. If he goes off that pill he immediately reverts to his pre-acne state. So, to make a long story short, this blog may truly turn into an ultra-low dose blog after next month. I got the feeling we will stop this drug for sure. If I revert to my old state I will need to go back on Antibiotics. After a period of time of an un-specified length my Doc would let me go back on the tane...... So for now I am enjoying the lack of oil and zits. Now mind you I still have scars and some holes in my nose from prior bouts with Acne. But man, do I look a lot better. I just look kinda rugged and tough, yeah, yeah thats it rugged and tough. Well somehow I got a hot wife, so I guess I can survive the look. Well thats all for now folks, pill 28 is on deck in about 6 hours. Stay strong all. Just know this, Accutane works. Low dose might be all you need.

Best Wishes
LowTane
6 Mar 2009
Brand:Sotret
Weight:90Kg = 200lbs
Sex:Male
Age:48
Dosage:20mg once daily

Day 29:
All extremely interesting OL. I started to have gastrointestinal problems from a high stress job coupled with poor diet. Diet sodas had replaced water and alcohol was a weekly event. Rosacea surfaced right on cue with the gastro problems. Many Rosaceans report the same thing, gastro first Rosacea next. Who knows, its all anecdotal....could simply be age. Well on another subject I have had some possible side effects today. A headache that lasted all day and some strangely weird wooziness and head scrambling. I had to cancel a lecture give a takehome test which tickled my collegiate captives to no end. The headache left after a good size meal and 2 asprin. The more I read about this drug the more I fear it. To many times I have read " the exact mechanism for Accutane's success is unknown". This drug has been out for 27 years. It is the number one selling drug for Roche. I have read as many as 5 million have taken this drug. It has been considered for removal from the market by the FDA. Debates have been fielded on the congressional floor over this drug. I think I am wise to be fearful. What scares me is the articles that discuss the permanence of the side effects. I for one cannot wait to get my dose lower. I have considered skip dosing, but I am afraid I may not get a long term remission if I play ping pong with the plasma levels. I don't know who reads this, but these are the things I think about.


I don't know if this helps anyone reading this blog. I can say this, my face is better than it has been in years. It feels great.....I just wonder will there be an ultimate cost. Google up side effects and lawsuits and Accutane before you even think about taking this drug.

Pill 29 on deck, maybe..........

Best Wishes
LowTane
[B][/B]7 Mar 2009
Brand:Sotret
Weight:90Kg = 200lbs
Sex:Male
Age:48
Dosage:20mg once daily

Day 30:

I took pill #29 last night. I have been reading horror stories all day off and on about this drug. I am having minimal side effects. I am still wondering if I should abandon this drug. I am thinking of skip dosing with two pills 20mg x 2 times weekly. To see if the dry oil free skin stays in place.
I may be taking a break from this drug to assess my feelings.



Best Wishes
LowTane:confused:
8 Mar 2009
Brand:Sotret
Weight:90Kg = 200lbs
Sex:Male
Age:48
Dosage:20mg once daily

Day 31:
So, I skipped pill number 30. I have decided that I wish to take the minimum amount of this drug. I will be taking 1 pill every Friday night. I am 100% clear after one month on this drug. I have decided that my sex drive is slightly dampened but functional after the 600mg that was ingested in the first month. I will bump the dosage from there if needed until I arrive at the minimum maintenace level required. I had another all day headache, I skipped a dose and the headache was gone the next day. Since the Derm has mentioned a second round of this drug as a matter of doing Accutane business I am not concerned about getting the drug. I guess this is what I really wanted all along. I decided to take charge of the dosage since I am the one that will have to pay in the long run. My Derm told me he has one patient taking one pill a week which shocked me. He didn't mention it before. Multiple studies address the efficacy of low bi-weekly dosing as an effective way to maintain and acne and Rosacea free state. It will take a lot longer to reach the total cummulative dose this way, but I feel starting low and moving up is better than starting high and moving down. I have found just to many horror stories and they have started to affect me. So, if were gonna go low lets go low and prove something. If I get a remission after an even lower dose regimen and I do it with the minimum amount of this horribly controversial drug the better. If I don't I can always go back and do the the the higher dose regimen if need be.... I probably won't though. Losing my bowel to Crohn's disease (the latest lawsuit by the way, just surf it up) kinda got to me. Until I get over that I am gonna have back off on the dose levels of this drug for mental satisfaction. We all know that Accutane at doses as high as 120mg's a day have been reported. We all know that Accutane clears horrible cases of Acne and changes lives. However, you gotta read the "Ask a Patient database" and read the 393 patient reports on this drug. I have major concerns..... More to come.............

Best Wishes
LowTane
Good to hear from ya Chooch. Thats cool.. Its nice to hear from other low dosers. But I must ask, what was your outcome after your accutane experience. Success, failure? Will you take it again. Did you have a remission etc... it would be cool to hear your story.

Old Lawyer, good to hear from you. You are right, there are side effects listed for every drug. There are lawsuits for multiple drugs on the market. Also, the sampling of horror stories is small in comparison to the number of patients who have prescribed this drug. I had wanted to go with a very low dose all along to feel this drug out. I know that long term antibiotics are no option either. I am torn between long term extremely low dose maintenance accutane and going for the high dose and hoping for a really long remission. I have skipped two pills so far and my headache and dizziness hasn't resurfaced. Could have just been a fluke and had nothing to do with Accutane. My derm is going to lower my dose next month anyway. So, still contemplating my next drug move. I do appreciate your reply. Good Luck...

9 Mar 2009
Brand:Sotret
Weight:90Kg = 200lbs
Sex:Male
Age:48
Dosage:20mg every 4 days.

Day 32:

Well if you have been following along at all you know I am taking liberties with the dosages of this drug. I have backed off on the 20mg daily to 20mg every 4 days. I have no increase in oil yet from the lower dosage. I have felt better on the lower dose. My facial redness (flushed look really) is more normal skin tone now. I am still dry and have very mild flaking. I am 100 percent clear and my pores have shrunk 85%. I am loving this part of this, all things are better. I do believe some of the extremely high dosages doctors have prescribed some patients have really caused some terrible problems. My reading shows that a lot of people get remission but still come full circle back to acne and oil. Many people do this drug several times with long breaks in between. My goal is to go low and stay low and check out my results compared to hopefully someone on higher dosages. Maybe old lawyer will stay around long enough to be that guinea pig. Well all for now......


Best Wishes
LowTane
10 Mar 2009
Brand:Sotret
Weight:90Kg = 200lbs
Sex:Male
Age:48
Dosage:20mg every 4 days

Shidoshi, thanks for giving some details. I have dropped my dosage as everyone knows if they are following this board. I am down to 20mg every 4 days. I was going to drop to 1 a week but changed my mind. So right around 2 a week it is.. At first I had no side effects at all, and I am not sure that the things I am experiencing are related to Accutane. Dizziness and balance problems, just slight but noticeable. Also, articulation and short term memory have had some weird lapses. The good that has happened is that I have become 100% clear with 30 pills which equals 600mg in just one month. I have been blown away as to how tortured my sebaceous glands were. Not only has Accutane shrunk my very large pores, it has caused spider veins to disappear as well. I also think a very large part of what I am going through now is directly related to the modern industrial diet. I am trying to change those things now. I have stopped drinking soda pop entirely. I drink more water, I have cut out sugar and almost all alcohol. Caffeine is gone. I am closing in on 50 and I hope that I can reverse years of damage through diet, lifestyle and maybe this drug. Well I may have screwed up the count, but I just took pill thirty. I will keep you posted as time goes on. I know this can get boring at this point. So, I would love to try to get you readers to share your Acne or Rosacea story and find out whether or not you have tried Accutane. Please join and log in an and share your information with us. Lets get this board growing, with almost 3000 views in one month you would think more of ya would stick around and share some information. Please do, it has been extemely helpful to me when individuals share their stories. Well, thats it for tonight.

Best Wishes
LowTane
12 Mar 2009
Brand:Sotret
Weight:90Kg = 200lbs
Sex:Male
Age:48
Dosage:20mg every 4 days

Chooch, heres the part I am talking about:

A total of 617 patients completed the study. In group 95% of patients achieved considerable improvement or complete remission of their acne;

Somewhere in that 95% were low dose Accutane users who acheived complete remission.

Where low dose is concerned my thinking is that the lower doses cause less damage to vital systems. I could tolerate a minute amount of strychnine once a week for a long time. However, a full cup would kill me instantly. I know that analogy stinks but its all I could come up with on short notice. Since the actual mechanism that makes Accutane effective is unknown, I believe it warrants extreme caution. I know there are quite a few individuals out there wishing they had never seen or heard of this drug. Many other countries are reporting responsible long term usage on much lower doses. I believe it is prudent and wise to re-think western methods. Many blogs report high dosage acne relapses. If someone starts on low dose, they can always later on try a higher dosage. At least they had time to feel out the drug and see if they can gain complete remission without as high a risk. I only posted two studies, there are more from Germany, UK, Turkey, Israel, Sweden etc... They are all advocating therapies that involve lower dosages, for very good reason I believe. So, for me, I feel much better trying the lower dose regimen before committing to a higher dose regimen. I certainly wouldn't recommend this drug to anyone without caution. I am 100 percent acne free on my entire body, with extremely minimal side effects thus far. I am maintaing that condition so far on 20mg's every 4 days. I bet based on how my body feels, that I could do it on even less. I intend to try and prove that point in the very near future. Dr. Plewigs study suggest some individuals maintain an acne free state with as little as 2.5mg's twice a week. To be fair, it is working for people with mild to moderat acne, I don't see a lot of low dose reports for really bad cystic acne. This drug completely cleard up my nasty oil acne riddled skin in one month. I am blown away. I had to take in 4 different studies which I printed out and show my Derm before he settled down to the idea of low dose. Now he seems to be fully on board with the idea. We could do American acne sufferers a big favor if we would all do the same thing. Educate them thar Doctors as to what the foreigners are up to with this controversial drug called Acctutane. Some Doc's may listen.

Well, enough conjecture for tonight.

Ps. I would rather take this drug for 8 years safely and remain acne free, than taking high dose for 6 months and possibly suffering from side effects for the rest of my life. However there are no real long term studies on low dose Accutane either. It could be just as risky.

Best Wishes
LowTane
14 Mar 2009
Brand:Sotret
Weight:90Kg = 200lbs
Sex:Male
Age:48
Dosage:20mg every 4 days

Well I could see how you could get bored reading these boards. I am still marching along with the low dose Accutane. I started with 20mg a day and cleard my skin, shrunk my pores all in one month and 600mgs. I have since reduced my dosage to 20mg every 4 days. I am really tolerating the lower dose scheduling on the 4 day cycle. Sex drive definitely is different. Things work, but the miindset has been affected. I am not sure what to make of it. Oh well only time will tell. I will lower the dosage further after the next Derm appt. I am still very wary of this drug, but man, wow.....what a difference in my life it has made. Confidence, attitude and appearance have all improved. I am way happier. My pores have shrunk, my blotchines has evened out, skin is soft and taught. Just didn't realize how swollen glands and hyperplasia can change your appearance. Well, thats all.

Best Wishes
LowTane
14 Mar 2009
Brand:Sotret
Weight:90Kg = 200lbs
Sex:Male
Age:48
Dosage:20mg every 4 days

Well Chooch, I am only guessing here...but I don't think lifting weights will increase testosterone levels much. But what the hell, it couldn't hurt to try it out. Now the supplements, thats not a bad idea. Hopefully whatever you choose will not contraindicate with the Accutane. I am able to get around the damped libido effect with an adjusted mental attitude.

Shidoshi, you couldn't be more correct about helping Accutane therapy out. The modern industrial diet has provided us with many new diseases. One look at nature and we can see that proper diet and exercise keeps the animal kingdom acne free. I have cut out soda pop entirely. I have cut processed sugar to the absolute minimum. We are held captive by the shelves at Safeway. Unless you can grow your own food and hunt regularly you are basically screwed where sodium, sugar, cholesterol and fat are concerned. On your pores, mine have been giving up little hard spicules that come out when washing or just gentle rubbing. You may be shocked at just how tight your pores will get. Unless you have taken this drug before. I can't remember if it was you that posted this is your second time on Accutane.

Well good luck all, time for work unfortunately. I will keep plugging away with the lower dose regimen. I intend to go so low my Acne returns. I am flirting with the idea of longterm micro-dose. If I can stay clear on 2mg twice a week like Dr. Plewig's study suggest, I might try it. I have already noticed that 20mg every 4 days instead of every day has improved my libido.

Side effects minimal, definite slight damping of the sex drive. Extemely mild headach once in a while. Lower lip slightly dry. Thats it as far as I can tell...

Still 100% clear, with oil at an absolute minimum with just over 600mgs and only 40 days in........ unbelievable.

Best Wishes
LowTane
16 Mar 2009
Brand:Sotret
Weight:90Kg = 200lbs
Sex:Male
Age:48
Dosage:20mg every 4 days

Good to hear from ya OldLawyer, I am glad all went well at the Docs. On the internet thing, most Doctors will say the same thing with the web reading. I tend to agree to a point, but doctors are people and they are fallable. I don't believe they are perfect in their overall outlook on many things. They do however run businesses, and that in itself is an issue. You probably have run into self appointed lawyers and have the same reaction. But, the web is an incredible source of information, anecdotal yes, and produced by lay people with no formal professional training. Its all true. My case in point would be this, either your Doctor just hasn't heard of this side effect before or the multitude of individuals who report loss of sex drive after engaing in Accutane therapy are wrong. Someone has to be right, only one or the other can be true. I can find lots of people reporting this side effect. It is possibly a rare side effect in comparison to the millions who have taken Accutane. To give her credit, she probably just hasn't run into it before and believes it is not a valid side effect. I can accept that, doesn't make all the individuals reporting this side effect wrong either. It has definitely affected my libido, which is something I am very tuned into, it is slight but noticeable. As long as it isn't permanent I have no problem with this effect. It's not uncommon for many different drugs to effect libido. Albeit temporary..... Many individuals support this finding in multilple places. The web has its place and for the most part Doctors are right in suggesting that you should take web reading with a grain of salt. However, Doctors learn most of what they learn about drugs from patient feedback. Studies conducted on drugs also rely somewhat on patient feedback. The same type of feedback that is posted by every day regular people on the web. So, in the end, it is a mixed bag of nuts. Doctors in the past never had to face patients armed with so much information, some reliable and some not so reliable. My Doctor prescribed my wife Ambien and her throat swelled up and she had trouble breathing. Ambiem reported this side effect on their website as anapyhlactic shock. They suggested discontinuing the drug immediately. My Doctor who had been prescribing Ambien for several years had never heard of this side effect before. He knows now.......

I remain cautious but optimistic about this amazing controversial drug. Everyone is different and may have different side effects.

Best Wishes
LowTane
17 Mar 2009
Brand:Sotret
Weight:90Kg = 200lbs
Sex:Male
Age:48
Dosage:20mg every 7 days

I have changed my dose to 20mg once a week. I am flirting with failure to see where my tolerance is.......... I do not feel strange about this experiment. I never ever wanted to take this drug in high dosages. I actually started higher than I wanted because the Derm set the dosage and i went along with it. Now curiously he would like to go lower. I think he is enamoured with a patient he has who takes one pill a week. He didn't suggest the dosage for this patient "X". I will ask him about it next visit. Very little has been done in the way of low dosage therapies in the United States according to my reading. Since I have backed off on the intial dosage I have even less side effects, lower lip, dampened libido, etc... I am 100% clear and my pores have gotten about as small as the poor stretched out things could get. It has been a significant improvement. I have decided to ride the extreme low dose experiment to the end. If I do not get a remission I will take a break and do a higher dose regimen possibly. I am not sure, as my opinion of this drug at higer dosages has not changed. But life certainly is better than it has been in a long long time. My attitude is so improved its difficult to describe. I was worn out on the constant oily swollen mess. I am normal again, I had forgotten what that felt like. Damn this stuff works like a charm. Sure would be nice to keep my colon, hair, libido and sanity in the process... heh, heh. OldLawyer, I hope you will stay in the background and step up when the time comes with some info as to your outcome. I hope all this bantering and posting hasn't driven you away. Well, I am gonna go to bed and wake up oil free and clear all on 40mgs (soon to be 20mgs a week) a week. I am excited to try the even lower dose the Derm has planned next. I will keep posting, not sure who is reading this pedantic drivel but what the hell. 4000 plus views, someone is looking at it............... Good Night!!

Best Wishes
LowTane:wave:
19 Mar 2009
Brand:Sotret
Weight:90Kg = 200lbs
Sex:Male
Age:48
Dosage:20mg every 7 days

Well, not much to say here. I am half way through the second month of my Accutane therapy. A total of 660mgs of Accutane have been consumed. As you know the title of this thread is "LowDose" Accutane. What is considered low dose? Anything less than the common standard of .5 to 1 milligram of Accutane for every Kilogram of body weight. You will find that researchers consider the total cummulative dose the key factor in remission rates. So, you would end up taking just as much Accutane as a high doser. It would just take a longer therapy to reach the total cummulative dose. So, whats the difference? Some Doctors believe that higher doses result in better and longer remission rates. There are many reports of successful remission at higher dosages. Recently reports on low dose studies have also shown good remission rates for low dosers. Some doctors in other countries are using low doses bi-weekly to sustain remission in some patients. These doctors have reported that monthly blood tests are not required at these low dosages. So, this is actually where I wish to end up if I don't get a remission. Start low, stay low and try to avoid any longterm side effects at all costs. Now it should be noted I have found no studies on longterm low dose Accutane therapies. Short term studies exist. Therein lies the problem. Long term lowdose could be as much a risk as short term high dose. All of these assertions should be taken with a grain of websalt. Ask lots of questions, get more than one doctor's opinion if possible. Try to ignore threads like this one and form your own opinions based on professional resources only. I paid to get the scientific journal access for Rosacea, Acne and the effects of low dose Accutane. I am convince it is right for me, with my obsessive mindset and all. How is it working so far? Wow! My life has improved immensely. But, inspite of it all. There are a multitude of people suing and winning over Accutane longterm side effects. It is easy to find what seems to be normal average everyday people reporting on different blogs horrific experiences with this drug. I can't ignore that entirely, I just can't. It is anecdotal and non-professional reporting to say the least. I still think there is some merit in paying heed to these stories. It is also fair to say that many high dosers report the return of there acne. Yet, it is also fair to say that many high dosers report long multi-year remissions with no long term side effects. It is also my speculation that successful Accutane users aren't as likely to report. They are to busy having fun. With 12,000,000 users world wide reported it seems that the percentage of bad experiences might be low. So, in the end, I know nothing other than what my own research has produced in the way of a perception of Accutane. I just know this, if engaging in certain behavior can result in a permanent long term outcome, I really want to dot my eyes and cross my tees before leaping into a therapy. My experience with doctors has shown me that it is okay to second guess them. This is where the "get a second opinion" cliche originated from. People second guessing their doctor. Please read up on possible longterm side effects. It is not a fantasy, many of these effects are listed right on the warning label in my very own Accutane prescription box. I am just a regular person trying to deal with a mentally devasting physical condition. Acutally two conditions. I have both Rosacea and Acne, and because of Accutane you would never know it. It has amazed me to no end......

I wish you the best...

LowTane
19 Mar 2009
Brand:Sotret
Weight:90Kg = 200lbs
Sex:Male
Age:48
Dosage:20mg every 7 days

I am not sure who is following this diatribe, but it is getting a bit thin on content. I will start posting weekly. Its getting too repetitive, all I can say is every day I am still 100% clear. I think this will get interesting again when I have terminated my low dose therapy. I leave you with this summary:

I started taking what is considered low dose Accutane for my size. This was made possible after I lobbied my Dermatologist with no less than 5 different studies on low dose Accutane from several different countries. After I dropped off the material I got a call and he set the dosage along the lines of the average low dose reported in the aforementioned studies. The first month I took 20mgs daily. I had immediate results. I had been given an antibiotic that doesn't contraindicate with Accutane in case the intial breakout was bad. He didn't want to do this at first, but it turns out I didn't need it. Accutane went to work gangbusters. With this dosage I had only some mild side effects. Slightly dampened libido, dry lower lip and an occasional mild headache. After the first month I was 100% clear. I then dropped my dosage to 20mg every 4 days. I remained clear...I then dropped it to 20mg every 7 days. I am still remaining clear at this dosage. This is where I am now.
I will continue my low dose experiment. When I have something to report I will certainly post it. Until then, I can only say you might consider low dosage if you have moderate or maybe even severe acne. You might consider low dosage if you have major oil problems. Hell you might consider low dosage if you have a hang nail......I have to say it has been a miracle for me so far. I fear the high dosage idea and will probably never ever opt for it. Doesn't mean that high dosage hasn't worked for people. It has.. I just believe that it makes permanent side effects even more possible. These are my own personal feelings, like I said, a grain of salt. I know nothing about this drug in all reality. I am just operating on my personal instincts. So, my observations only serve one purpose. They are cathartic for me. It may however help someone to hear someone else's story. Please read read read and get lots of doctor's opinions before saturating your body with this controversial miracle drug called Accutane.

I wish everyone the best.
LowTane
24 Mar 2009
Brand:Sotret
Weight:90Kg = 200lbs
Sex:Male
Age:48
Dosage:20mg every 2 days

Good to hear from you OL, glad all is well. I have nothing major to report, bumped my dosage back up to 20mg every two days instead of 7. This was based on reading the local dermatologists boards and gaining a consensus. Many believe the total cummulative dose is the ticket. Doesn't seem to matter how you get there, as long as you do. Mild side effects and still one hundred percent clear. Still having a small glass of Cab Sauv once in a while. Down in weight as well. Libido functional with slightly diminished drive. Well thats all folks..........

Best Wishes
LowTane





All times are GMT -7. The time now is 06:22 PM.





2019 MH Sub I, LLC dba Internet Brands. All rights reserved.
Do not copy or redistribute in any form!