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Low Dose Accutane
Feb 6, 2009
6 Feb 2009
Hi, I have just taken my first low dose of Accutane
Brand:Sotret
Weight:90Kg=200lbs
Sex:Male
Age:48
Dosage:20mg once daily
Supplements:None

Day 1
Chronic oily skin, blotting on the hour. I have mild Rosacea and more severe Acne Vulgaris of the nose and chin. My dermatologist in the USA had no real off label experience with low and microdose accutane. I brought him multiple studies from Israel, Turkey, UK and more.... he was interested. I have a back-up of Eythromyacin, I am hoping not to use it. I have been on Doxycylcline for the last year (this is not allowed with Accutane) since being diagnosed with Rosacea. My derm will only allow for a one month antibiotic security blanket. Eythromyacin does not have contraindications with Accutane, when its gone I have to ride it out. I am Professor at a local college, needless to say it is difficult to have skin problems and have to lecture in front of crowds. I hope I am lucky and can avoid the dreaded intial outbreak so many Accutane users report.

Best Wishes
LowTane

Declarative statement: I am not recommending this drug. I am only reporting results in the most objective manner I can muster. I do believe this drug can be dangerous. I am taking this risk of my own accord. Please read other blogs that discuss the seriousness of possible long term side effects.
7 Feb 2009
Brand:Sotret
Weight:90Kg=200lbs
Sex:Male
Age:48
Dosage:20mg once daily
Supplements:None
New behavior: No alcohol or caffeine

Day 2:
I took my first Accutane 20mg pill last night at 9:00 with a bowl of oatmeal some apples and a big glass of water. Slept fine, no reported side effects. I will continue to take my dosage at night before bed. My acne is very controlled right now, I have been on daily Doxycycline for months. So, I guess so far so good.

Day 2 continued: Rosaceans I did have a flushing episode today, it was short and faded within minutes. I don't know if I can blame the accutane or not. I no longer have the security blanket of Doxycycline since it is forbidden with Accutane. I have one month of Eythromyacin but I am holding on to it for emergency situations. My Derm says thats all I get. Needless to say I was bummed out to have the flush happen. The Rosacea forums suggest even smaller doses of Accutane for Rosacea. I have both acne and Rosacea so I am torn between low dose recommendations. I also had my upper lip go slightly dry. I used lip balm and wondered if I was imagining this (I mean I have only taken one pill for Gods sake) since it is one of the most common side effects listed for Accutane users.

I just took my second pill, I have chosen to take Accutane just before bed. If there are side effects I was hoping to sleep through some of them......more to come.

Best Wishes
LowTane

Declarative statement: I am not recommending this drug. I am only reporting results in the most objective manner I can muster. I do believe this drug can be dangerous. I am taking this risk of my own accord. Please read other blogs that discuss the seriousness of possible long term side effects.
9 Feb 2009
Brand:Sotret
Weight:90Kg=200lbs
Sex:Male
Age:48
Dosage:20mg once daily
New behavior: Zinc, Vitamin E, B and C supplements

Day 4:
Well its the morning of the 4th day. I have taken 3 20mg Sotret Acctuane pills. Slept like a baby, no sign of side effects other than the slightly dry lips. I am waiting for my acne to go crazy since I have stopped all antibiotics. I seem to be in a lull. Good! I don't want to post imaginary results but I gotta say I am waking up with less oil on my face already. Usually I am soaked. It would be hard to believe that this drug in only 3 pills could reduce my oil output already. However, if it can cause dry lips almost instantly then maybe a slight result could be possible already. I have no side effects other than the lips. No headaches, vision, nausea or pain anywhere so far. I have started to eat very healthy, low fat, grains and fruits are the route I am following. I am looking into supplements as well. I am thinking that a healthy diet and attitude might help with this therapy. I know that without antibiotics my acne should explode anytime now. We shall see.....

Best Wishes
LowTane

Declarative statement: I am not recommending this drug. I am only reporting results in the most objective manner I can muster. I do believe this drug can be dangerous. I am taking this risk of my own accord. Please read other blogs that discuss the seriousness of possible long term side effects.
10 Feb 2009
Brand:Sotret
Weight:90Kg = 200lbs
Sex:Male
Age:48
Dosage:20mg once daily
New behavior: No soda pop of any kind

Day 5:
Well I took my 4th pill last night. I know it sounds crazy but I can see changes already. I have even more fear of this drug than I had in the first place. It has to be powerful to have these effects in the short term. I definitely am waking up with less oil on my face. My first day of work was met with 50 percent less blotting with tissues. I had several events where I felt I had flushed (rosaceans pay heed) under some job stress but checking in the bathroom showed just regular looking skin. My Acne has not burst forth in the abscence antibiotics yet. Pores seem slightly smaller already. The mild lip drying is still present. I have no reported side effects with the possible exception of the lip drying and maybe one other. My libido seems to have taken several steps backwards. It should be noted that all of the results I am reporting could be due to just coincendental factors. Inside though, I really think it is this drug. I have read other Accutane logs with similar results. I am trying to be very objective, I pay attention to small details. One other thing that is definitely happening is the anti-imflammatory effect. My skin color is more even and red veined areas are looking less apparent than they have in years. I realize this is only 80 milligrams of Accutane and the diet changes could be part of this...... I don't know. It seems impossible to already be feeling the effects of this drug, but my oil ouput and skin color has shown changes. I know, I have to look in the mirror every day. I will continue to log results, I expect the suspected effects to become more apparent as time goes on. Then I can report with more confidence what I am already suspecting. I remain mildly optimistic wondering about what I am experiencing. I am thinking of asking my Derm to reduce the dosage to 10mg.

Best Wishes
LowTane

Declarative statement: I am not recommending this drug. I am only reporting results in the most objective manner I can muster. I do believe this drug can be dangerous. I am taking this risk of my own accord. Please read other blogs that discuss the seriousness of possible long term side effects.
i just came back to healthboards for something else.... the last time i was on was back in 2000, 2001 for acne issues. this board was a great help but i must tell you- ACCUTANE IS A CURE! it was a miracle drug for me and now whenever i get compliments on my skin (more often than you would ever think) i just can't believe it.

stay strong....
11 Feb 2009
Brand:Sotret
Weight:90Kg = 200lbs
Sex:Male
Age:48
Dosage:20mg once daily
New behavior:None today

Day 6:
Well, I will be taking my 6th pill in a few minutes. I gotta tell ya, you probably won't believe me though. My pores which I double checked with my Wife are reduced by over 50 percent. I was blotting 10 times a day with tissues to soak up oil. I now blot 4 to 5 times a day during work. My acne was under control from a year on Doxycycline, so I didn't have much when I started Accutane. However, by now I should be breaking out gang busters with Acne Vulgaris all over my nose. Ususally my nose is throbbing from the swollen sebaceous glands. It is feeling of normal size again. It actually looks smaller. It is like a switch has been thrown and my oil glands are being told to stop. My pores are shrinking at a rapid rate. A 100mg dose (20mg once a day) of this drug has caused these reactions in only 5 days. I say it again, I am very scared of a drug that has this powerful effect in that period of time. To the rosaceans who may be vieiwing this log, I feel extreme hot flushes in the cheek but not my nose, however when I check to see how bad it is, it is insignificant. I look mildly flushed compared to how I used to look. My side effects are extremely mild to none. Slightly dry upper lip is all I have..... I have read many horror stories about this drug, I won't go into the details. So, my fear levels are high. I am happy and at the same time scared to death. I really want to take even lower doses. I have considered getting gelatin caps and a syringe and drawing out 5mg doses to put in the caps. I wished this came in pill form so I could break them into pieces. I am not sure what I am going to do yet. It almost feels as if my body needed this, it makes me wonder how it works. Its like something out of whack has been corrected. Some individuals lives are ruined by this drug. I find that it is the high dosers who report the worst problems. Low dose this drug might just be heaven sent. My job is already one hundred percent better. My wife is throwing a party this weekend and I am actually looking forward to it. Miracle or curse......we shall see.:confused:

Declarative statement: I am not recommending this drug. I am only reporting results in the most objective manner I can muster. I do believe this drug can be dangerous. I am taking this risk of my own accord. Please read other blogs that discuss the seriousness of possible long term side effects.

Best Wishes
LowTane
12 Feb 2009
Brand:Sotret
Weight:90Kg = 200lbs
Sex:Male
Age:48
Dosage:20mg once daily
New behavior:None today


Day 7:
I have had mild rosy cheeks and nose today every so often. Once for an hour or so. I do believe that the magic dose for my rosacea symptoms is probably lower. Most Rosacea forums report success with low doses. The trick is if you have both Acne Vulgaris and Rosacea to find a dose that is just right for both afflictions. Low dose studies show that 2.5 to 10 milligrams for varying sizes of people seems to work very well for Rosacea. Low dose studies for Acne seem to hover around 10 to 20 milligrams for varying sizes of people. I am going to ask for a reduction to 10 milligrams this month when I see my Derm. My skin is already looking better just because of the greasiness being minimized. Pores aren't so hideous. If this drug has this affect this soon, I wonder how fast things could go bad if I stopped taking it right now? The throbbing swollen feeling my nose has had for years is minimal now. Skin is dry and feeling smoother already. My wife has noticed the difference too. I kid you not, this is like a biological switch has been thrown. I have been waiting for the acne to explode, so far nothing. If I don't explode in another week with acne I will begin to believe that Accutane is suppressing the bacteria that causes acne somehow. Well for now I will stay on this dosage. It is so early in this trial that some readers must think I am nuts and imagining the results. I have considered that maybe I am just hitting one of those acne free windows and this is a coincedence. One thing I have noticed is the parts of my face that are not normally oily are very dry and smooth. My whole face feels tight. I am using Cetaphil on my cheeks. If my Derm won't go for a reduction in dosage I may move to skip dosing and take 20mg every other day. Well thats all for now, gotta go take pill number 7.
:wave:

Ps. I mentioned a Libido scare a few posts ago, well it checks out fine. (Well, for a 48 year old anyways!) ;)

Best Wishes
LowTane
14 Feb 2009
Brand:Sotret
Weight:90Kg = 200lbs
Sex:Male
Age:48
Dosage:20mg once daily
New behavior:Optimism :D


Day 8 & 9:
Well its the morning of day 9 and I have taken 8 Acctuane pills for a total cumlative dose of 160 milligrams. I still take it at night before bed with a small meal. Well, I am in love with this drug, fear and all. Now, my face is never gonna be scar free without some intervention of some kind. I have had acne to long on my nose. However, Accutane is like a chemical facial. My pores are shrinking and my oil is more like a normal human at this point. I am in shock that this drug could be so rapidly effective. Blotches are already lighter than before and getting better as we go on. I can no longer even tell I am taking this drug. I have no side effects at all, not even dry lips. I have mildly insignificant micro flaking of the skin. So, inspite of the fear I am one happy camper. To Rosaceans, yesterday was flush free, and also, Acne Vulgaris seems to be in hiding. I have had a few minor pimples that have come out of the skin and been washed away. Now it should be noted that I have stopped a lot of other behavior as well. This could be helping the results along. At this point I can't really list a single problem. Now I know this could all go bad overnite so I am not going to get to euphoric and tell someone to run out and get on this drug. But I will say this, I will never take high doses of this drug ever. I made the commitment when I started that if low dose didn't work then tough luck. I have read at least 3 to 4 hundred hours on this subject. To many questions out there still even after almost 30 years of data collected on this drug. But I am hopeful that my derm may consider micro-dose long term if it will help manage my Rosacea and Acne Vulgaris. Low dose is the answer in my opinion. One more thing, the stories about diminished sex drive may be true, but for me so far that is not the case. All seems perfectly normal. Well thats all for now folks, I think I will take my (almost) oil free face out into the world for a few errands. Stay strong all............

Ps. Keep in mind that a lot more people have taken this drug than the horror stories support. If the several million people that have taken it so far all had very poor results I think this drug would be off the market for good. The reported birth defects seem to be the biggest negative factor that gets reported. I also suspect that the really high doses are causing the majority of problems where other side effects are reported. Purely an opinion from my personal research. Take it with a grain of salt, cuz I really don't know enough.

Best Wishes
LowTane :p
14 Feb 2009
Brand:Sotret
Weight:90Kg = 200lbs
Sex:Male
Age:48
Dosage:20mg once daily


Day10:
Well I suppose this log could get boring for individuals following it. To the Rosaceans reading this: I ate any an all forbidden foods and flushing seems suppressed. To the Acne crowd my acne is still in check with a few pimples here and there that are small and come out rather easily. The biggest change is the reduction in oil. That is undeniable...... with this reduction I expect comes the hopeful changes that make this drug irresistable. I can now at this juncture report that side effects are undetectable. Even the dry lips are gone. Sex drive is still intact. Eventually I will be a long termer who can report whether or not there were phantom side effects that pop up somewhere down the road long after I stop taking this controversial frightening yet wonderful drug. Hard to believe that it's a natural substance in our bodies and directly related to vitamin "A". I am feeling a lot better on this drug than the longterm antibiotics I had been taking. You can always tell you are on the antibiotics, but low dose Accutane is becoming undetectable. Well pill 9 was consumed last night and all is still okay.

Best Wishes
LowTane:wave:
17 Feb 2009
Brand:Sotret
Weight:90Kg = 200lbs
Sex:Male
Age:48
Dosage:20mg once daily

Day 12:
Well I took pill #11 last night. I am now getting acne on my chin and nose. I suspect the cessation of Doxycycline has allowed the bacterial populations to come back. Since Accutane is not an antibiotic I am bound to catch a few. They hurt...... Accutane cuts sebaceous activity and thereby reducing the food source for the bacteria that makes acne possible. It's hard to believe I am almost 50 and I am going through the trials and tribulations of a teenager. I will continue my regimen and play this game to the end. I hope this is the initial dreaded breakout I read about in other forums. Right now my oil is extemely reduced but not eliminated. Not on this dose and not at this time. I will continue to report changes in physiology as I experience them. I hope this helps someone out there who may be contemplating Accutane. I have calculated that the total cummulative dose of Accutane of 120mg per kg of body weight for best permanent remission opportunity would not occur for 540 days on this dosage. Something to talk to the Derm about.

Day 12: Cont-
Its time for pill number 12 here shortly. It should be noted that absorbtion can be increased by taking Accutane with a fatty meal. Hmmmmm...you can somewhat adust your dosage just by food selection. Well, the acne doesn't hurt as much as it did earlier. Its not very red either. Seems this drug is a wonderful anti-inflammatory substance. Face is still mildly itchy, lips are no longer dry at all. My face is better in just under two weeks on this drug than it has been in a long time. Well thats all for today. Pill #12 is on deck.

Best



Best Wishes
LowTane
18 Feb 2009
Brand:Sotret
Weight:90Kg = 200lbs
Sex:Male
Age:48
Dosage:20mg once daily

Day 13:
I gotta say, that Accutane changes the normal process for a zit. I was already for a long drawn out process for my new acne. It started very painful as usual, but.... my zits are drying up quick. Its as if they are drying from the inside out. Pain came and went. The normal expected redness and swelling is very mild in comparison to past acne events. Wow, I am loving this drug. Pores that I expected would need surgery are much, much reduced in size and appearance. Oil is still very well controlled. I have no side effects whatsoever. My attitude is improved 100%. After reading all the horror stories online I was braced for the worst. I might as well be taking a vitamin pill. I am thinking that the Europeans have it right. We are giving much to high of dosages in the United States of this powerful drug. Pill #13 goes down tonight.

Day 13: cont-
I just took pill #13 a few moments ago. I have two zits on the chin and 3 on the nose. They are not that red though. It really is a lot easier to deal with the zits on this drug. I hope this does not last for weeks. It would be nice to get past the intial breakout. To the Rosaceans. No flushing at all, no hot skin...nothing. It seems this drug does control Rosacea. The downside is I have heard it doesn't cure it like it can Acne. When all is said and done the next hurdle may be getting a Derm to commit to long term Microdose Tane. Well, good nite.


Best Wishes
LowTane:D
19 Feb 2009
Brand:Sotret
Weight:90Kg = 200lbs
Sex:Male
Age:48
Dosage:20mg once daily
Symptom: Dry lower lip

Well my lower lip is getting dry, slightly cracked. Not bad, I am using lip balm again. The round of acne that I have is pale and not so noticeable. I still think the ant-inflammatory of this drug is amazing. It helps to reduce redness. Zits rotate pretty fast, come and go fairly quickly. I wish I had taken pictures of my face to start with.... sorry. Quite a few views of this log have occurred by numerous individuals. I hope this helps someone who may be considering "Low Dose" Accutane. The Accutane experience has controled my oil slick of a face very rapidly. Still no major side effects and the sex drive is still intact. No depression, no headaches, nothing but the desired effects so far. I realize this could all change, so I will keep reporting. Pill #14 tonight.

Best Wishes
LowTane:cool:
I started on Monday 2/16. I am 48, male,190 lbs and am on 40mg/day. My systoms are similar to your except I was on tetracycline for 11 years (absurd, I know) and everything else that did not work. My breakouts were usually not bad, mostly on the nose and trunk. My face started to get really read last October and it took me 4 months to get a derm appt. Since nothing else worked, including prescription creams, they said this was the best option.

I decided to quit drinking while I am on it...will make friday nights rather dull, but I like my liver.

The first day I had some mild headaches. The second day I broke out a little, but I`m not sure if it is from the accutane or the fact that I stopped using everything else. Today I was a little more broken out but they went as quickly as they came, which was strange. My eyes get very dry about an hour after I take it (with dinner) and that lasts for an hour or 2. My skin is less oily, for now. I sleep like a rock.

I was told to drink a lot of water and exercise and eat well.

My 19 year old daughter just finished up. She was never that bad but nothing got rid of her mild acne so she tried it and has flawless skin.

Good luck. Keep in touch.



[QUOTE=LowTane;3877069]6 Feb 2009
Hi, I have just taken my first low dose of Accutane
Brand:Sotret
Weight:90Kg=200lbs
Sex:Male
Age:48
Dosage:20mg once daily
Supplements:None

Day 1
Chronic oily skin, blotting on the hour. I have mild Rosacea and more severe Acne Vulgaris of the nose and chin. My dermatologist in the USA had no real off label experience with low and microdose accutane. I brought him multiple studies from Israel, Turkey, UK and more.... he was interested. I have a back-up of Eythromyacin, I am hoping not to use it. I have been on Doxycylcline for the last year (this is not allowed with Accutane) since being diagnosed with Rosacea. My derm will only allow for a one month antibiotic security blanket. Eythromyacin does not have contraindications with Accutane, when its gone I have to ride it out. I am Professor at a local college, needless to say it is difficult to have skin problems and have to lecture in front of crowds. I hope I am lucky and can avoid the dreaded intial outbreak so many Accutane users report.

Best Wishes
LowTane

Declarative statement: I am not recommending this drug. I am only reporting results in the most objective manner I can muster. I do belive this drug can be dangerous. I am taking this risk of my own accord. Please read other blogs that discuss the seriousness of possible long term side effects.[/QUOTE]
Old Lawyer, I am glad you chimed in...please do keep us updated. My wife and I were looking at my pores tonight. Honest to God I am in shock, my wife told me that I have no pores left. I had holes in my nose, I was checking into plastic surgery. I have also put alcohol on a shelf, maybe for good. I feel like drinking may have caused some of my Rosacea issues. I feel great and have lost weight by cutting out the weekly drinking. Good ta hear from ya.......:)

23 Feb 2009
Brand:Sotret
Weight:90Kg = 200lbs
Sex:Male
Age:48
Dosage:20mg once daily
Symptoms: Dry lower lip

Day 19:
Well, the pores are shocking, the oil is gone. Sex drive still seems functional, but the fear subsists. I don't know what to say, I am blown away. My Rosacea symptoms are non-existant. My attitude has just gotten better by the day. Wow, you probably think I am nuts! If I had known this option existed before, I would have stepped up to the plate a long time ago. 20mg daily has made a huge impact on my oily greasy face. It feels great to be off of antibiotics. I know I am repeating myself but I don't know what else to say. An ugly vein in my nose has all but dissappeared. I am waiting for the other shoe to drop. Acne scars are less apparent. This may be because of the lack of oil, scars and imperfections show up much better when coated with shiny oil. It also could be the tightening of the skin. Pores have closed up at an incredible rate. Its funny, now I can only think of the end of the thearapy and what will happen if I don't get the remission. Well, I should get 10 months minimum out of this, thats how long my derm has me scheduled for........ Pill #18 down the hatch.:bouncing:


Best Wished
LowTane
BlueEyz please elaborate more info, brand of Accutane, dosage, type of acne etc... we are curious as to the details.

Thanks
LowTane
From what I can recall, I fluctuated between taking two 20 mg pills up to one or two 40 mg Accutane capsules a day. I wish I could remember more specifically, but I've tried so many different treatments that they've all sort of blurred together, and this was also about 6 years ago. I had blackheads, small whiteheads, and some cystic acne at the time, but when I took the Accutane, I developed a LOT of cystic acne. After I was done, my skin calmed down for about 3 months, and then I began breaking out "per usual."
Thanks Blueyz..........

24 Feb 2009
Brand:Sotret
Weight:90Kg = 200lbs
Sex:Male
Age:48
Dosage:20mg once daily
Symptoms: Dry lower lip
Behavior: Cetaphil soap and moisturizer b4 bed



Day 20:
I never did use the emergency Erythromyacin my Derm gave me for the intial outbreak.
No side effects other than lower lip slightly dry.
Sex drive still functional.
Micro-flaking on nose and chin (only the areas where acne presents).
Oil reduced 95%
Rosacea symptoms = Zero!
Acne breaks and drys in 24 to 36 hours.
Pores and scarring have been affected significantly.
Confidence has improved 85 percent.
Fun factor and socialability improved beyond measure.
Pessimism diminished somewhat. (Still I do not take this drug lightly!)

Pill # 20 is on deck in one hour! :wave:

My take and speculative wishful thinking: I honestly am starting to feel that this drug at this low dose is not going to kill me. I have 100's of hours (really I do) of reading blogs and research papers on this subject. I think that the high dosage approach is where the problems can really present themselves. Even though some individuals report no problems in the long term from higher dosages. I don't think I would be comfortable on this controversial drug at the 5mg/Kg of body weight norm here in America. My hopes are at the very worse, a 5mg every other day maintenance dose (or less) in the long term if required. I am aware I could still have problems in the long term. However, this drug is 30 years old. Millions have taken it, wouldn't this be a much bigger story if everyone had long term side effects. The web shows a small group of individuals (in comparison to the number of individuals who have taken this drug) blaming this drug for every bad experience they have had post Accutane. I am not saying they are wrong, I am wondering if they are just a small percentage of a very large group. Just a thought..................

Best Wishes
LowTane

Declarative statement: I am not recommending this drug. I am only reporting results in the most objective manner I can muster. I do believe this drug can be dangerous. I am taking this risk of my own accord. Please read other blogs that discuss the seriousness of possible long and short term side effects.
Thanks for the update OldLawyer, very informative. See below for recent event:


25 Feb 2009
Brand:Sotret
Weight:90Kg = 200lbs
Sex:Male
Age:48
Dosage:20mg once daily
Symptoms: Dry lower lip
Behavior: Cetaphil soap and moisturizer b4 bed

Day 21:
I hate even reporting on this subject but I gotta. This affects both people in a relationship. I had noticed some sensation changes with this drug during intimacy in the very first days of usage. In my last encounter there was failure and I did not bother to try and finish the event. Now, you should know to put this in context that I am 48. However, this does not happen to me. I am and always have been right up till I started taking Accutane as regular as a clock, 3 to 4 times a week. What I also noticed, and maybe this is more frightening than the failure is that I didn't care. Normally, interruption of this event would cause extreme frustration. In this case it didn't bother me. You don't mind passing up a meal if your not hungry. This is significant, I am very prolific and have been my whole life. So, lets think about this. There are reports and possibly lawsuits because some people are reporting that the loss of sex drive continues even after the drug is stopped. It does make some sense, individuals taking this drug hope for remission. Meaning, after you stop the drug the benefits persist. The exact mechanism for how this drug works is not known. Oil production (the chief cause of acne) has been tied to testosterone and estrogen, which are also tied to sexual appetite. So if there is remission and longterm suppression of acne it stands to reason that suppressed sex drive could also be a result. Of course this is unprofessional layman speculation and should be taken with a grain of salt. It is to early to tell if this was just some mental event, its possible I suppose. I am very self aware though and know my body very well. I will test this out with stronger stimuli and see what the results are (I can't go into details here I am embarrassed to even be writing this as it is) after that experiment. If you surf up Accutane and sex drive, impotence etc.. you will definitely find results. I hope to give you the most accurate objective observations that I can. So, at this point I must say that I am very concerned and have some serious thinking to do. I will monitor this trend closely and discuss it with my Derm. I will continue to report to you as accurately as I can my experience on Accutane.

Note: If you are reading this, please don't jump to conclusions yet. All people respond to drugs differently. Women and men will have different attitudes about this observation. Some individuals report no problems with sexual activity while on or post Accutane.

Update: Read ahead, possible false alarm on the impotence scare.

Best Wishes
LowTane :(
Hi Low tane
Been reading your posts with interest as i've just started on low dose accutane myself.
Quick bit of info about myself;
I'm a 26 year old male who has suffered from mild/moderate acne with excessively oily skin for around 15 years. Weigh 75Kg
Took my 6th 20mg accutane pill today - brand i'm using is Roche.
From the first day i noticed a reduction in oil and everything seemed to be going great until yesterday. Noticed that i seem to be getting some rosacea symptoms that i didn't have before. My cheeks seem really hot and i look slightly read (not as much as i feel!). If this carries on i may reduce my dose to 1 tablet every 2 days so my dose would be 10mg per day. That's the only side effect i've experienced, still have acne on my forehead, but spots seem to be drying up nicely. Will keep posting on here. Be interesting to compare my progress with yours as i'm not too far behind you!
Well OldLawyer, thanks for the comments. I am jumpier than a longtailed cat in a room full of rocking chairs over this medication. I mean its just a fact, Accutane is controversial, period. I gotta say though, wow! What an amazing job it has done in healing my tortured schnoz and chin. I still blot out of habit sometimes, minimal oil is present. My nose is very narrow now. Still healing a few places and blotches are dimming. Luvvin it..........!!!!


26 Feb 2009
Brand:Sotret
Weight:90Kg = 200lbs
Sex:Male
Age:48
Dosage:20mg once daily
Symptoms:Lower lip is a lot dryer than before. Cracking a little now.

Day 21:

Well pill 21 is on deck, I may have messed up the count in prior posts. I am done freaking out for now over my private intimate life. For now..... Face and confidence are on a parallel path. Life is better than it has been in quite sometime. Dry lips are easily handled. No other side effects can be detected. Sleep just fine, no headaches or body aches like some individuals report. No night blindess whatsoever. I am really happy with the results. If there is no final potential price to pay for this amazing miracle drug I will be extemely greatful. I see people on the streets and in the classroom that have oily skin and blotchy painful looking acne and I want to say something to these people. Like "Do you realize you could possibly be completely clear of acne in less than a month?" Then I think about the controversy surrounding this drug and I keep my mouth shut. I can't recommend this drug because it scares the crap outta me............. I can report what I experience though and hope individuals that decide to use this drug based on what others say still realize it could turnout bad for them, regardless of the success others may have. Thats the bottom line..........

Best Wishes
LowTane
OldLawyer, good to hear from ya.... thanks for chiming in for Drew. Its good to hear results from more than one person. Thanks for sharing the details of your therapy.

26 Feb 2009
Brand:Sotret
Weight:90Kg = 200lbs
Sex:Male
Age:48
Dosage:20mg once daily


Day 22:
Well, I have realized that I will get to a point where my face will not advance any further. Once the Acne is gone and the oil has dryed up the only thing left will be scars. At this point my reporting will only consist of observable physiological ramifications that may present during the completion of this therapy. The next phase of interesting material may consist of posts logged after Accutane therapy is complete. Will there be a remission? Will OldLawyer's more conventional dosage get him a remission? Will my Rosacea symptoms come back while the Acne stays in remission? Will I become impotent? Will other long term side effects present months or years after suspension of Accutane therapy? Like my hair falling out as some individuals report. Or, is my Dermatologist correct with 20 years of Accutane experience when he says "poppycock?".......Will I need and Will I be able to talk my doctor into long term ultra-lowdose acctuane? If he does, will it help me to remain oil and rosacea free? Like say 2mg a day, 1/10th what I am taking now. Will the return of my youthful dashing good looks cause me to trade my wife in for a younger beautiful woman? Will I get Laser Genesis to erase the remaing micro-scarring? Or, will an asteroid hit the planet making all of these questions moot? More importantly, will I break 80 in golf? Well, I am rambling now. These are questions that my abstract musings produce over time. On a serious note, as I walked down the hallway at my Dermatologist office I heard him say over my shoulder "Accutane will change your life". I looked back him and I thought, I'm worried about it ruining my life. So here I sit looking at my new face thinking, regardless of the fear factor here, wow!, this drug has changed my life, it has for now given it back. I haven't been this happy in a long long time.

I will take pill 22 in about 30 minutes.

Keep the Faith
LowTane :rolleyes:
28 Feb 2009
Brand:Sotret
Weight:90Kg = 200lbs
Sex:Male
Age:48
Dosage:20mg once daily

Day 23 and Pill #23:
Well, if any of you have been following this Accutane log you know by now I am an obsessive compulsive type of individual. I was agonizing over a momentary lapse in Libido due to all the web stories pertaining to that issue. Well I am happy to say that everything is normal, no problems. You can bet that if things go south (no pun intended) I will report those results. I did have Rosacea type flushing of the cheeks today following a dcaf latte. But I have also taken to having a 4 ounce glass of Cabernet Sauvignon before bed. I am wondering if either could be the cause of the flushing today. The Acne is in complete remission, I am luvvin it...........My nose is so narrow its hard to believe. I still have a few minor blemishes trying to fade away, but no new ones. I had a few minor blemishes on my back and they have dried up. Flaking of the nose etc... Well time for #23 and bed.
Just wanted to put my two cents in. I used Accutane 3 times! The first two times, a very low dose..the third time, much higher. Almost a year in between each of my rounds, and each and every time by the time the year ended, my skin was twice as bad as I started! It seems for me, that as soon as the oil glands start to "repair" themsevles- my acne, which is mostly cystic- comes back tenfold.
My derm suggested I try Photodynamic Therapy ALA , which is a more permanent solution. I had my first treatment on Friday...it was slightly painful, but by the time it was over, it wasnt so bad...the next day, I was red and flushed, like a sunburn, however no pain at all. Ive been moisturizing like crazy! What I do notice is that there isnt a blackhead or whitehead on my face- the two cysts which were starting to form went down significantly and the few actual pimples which were there dried up over night and are virtually gone. The scarring, which is what Im most concerned about - has not changed at this point, but my derm did say it takes up to a week or two to see any results and which probably take 3 treatments spaced 2 weeks apart to show significant differnce.
Im stoked to see if this works. There are NO physiological side effects to this procedure...
best of luck to everyone-
nikki
Thanks Nikki for the input. I think my reading agrees with Nikki's two cents. Many inidividuals report remissions of up to 1 to 2 years. Although my Acne is not cystic my oil production is over the top. My intent is to change my life style and see if that helps at all. I have resigned my self to the fact that my situation might not change until I am a very old man and my testosterone and hormonal values change. But hey, who knows what the future holds. I also have high hopes for sustained microdose therapy of Accutane in the long term. Whether my Derm would go for that is another question. Some Doctors are reporting success in maitenance of Acne and Rosacea in the longterm with Accutane. I have read that with ultra-low doses some doctors are not requiring blood tests. So, we shall see what becomes me..... when this is all over in about 9 more months. So far, I am overwhelmingly greatful for the break in oil production and resultant Acne.

Best Wishes
LowTane
Likewise Nikki, I wish you the best of luck. Thanks a ton for bringing up therapy for Acne I had never heard of..........
1 Mar 2009
Brand:Sotret
Weight:90Kg = 200lbs
Sex:Male
Age:48
Dosage:20mg once daily

Day 24:
Pill 24 on deck, not a ton to report other than a few zits arrived and exited fairly quickly. Oil is still highly contolled, no side effects I can perceive easily. Little flaking here and there, lower lip etc.. I am definitely thinking already about the end of this therapy. I feel like the low dose over the longterm is easier on the body than the higher doses. Its hard to tell at this point that I am taking a drug at all. Rosacea with slight flushing here an there, but no papules or bumps anywhere. Pores have shrunk a lot, it will be interesting to see if they can even shrink more. Libido, check.. all good. I will continue to report as long as I can find something to say of substance. I feel like this is just a repeat at this point. So, I have taken to try and post something to read that may be meaningful. Well, its time.....

BestWishes
LowTane
"Generally accutane is introduced at a very low dose and is steadily increased over many weeks. There actually are no specific guidelines as to how much should be prescribed to each person. However, research shows that a total dose of around 120mg per kilogram of an individualís body weight is enough to banish acne for some time. "

OK, well if I do the math, I will need to take about 10,300 mgs to be "cured." That would be an average of about 57.25 mgs per day for 6 months. I am taking 40 mgs per day now, and I know I won`t be on that level for the 9 months it would take to reach optimum dosage. My guess is I will do a few months at 60 to 80mgs per day once the docs confirm my body has tolerated the lower dosage so well. My daughter, who weighs 110, did most months at 20mg and a few at 40mg, when the 20 stopped showing improvement. They cut her back down to 20mg before she finished.

Anyway, I go back to the doc in 2 weeks....bloodtest next week. I assume I will be ok with blood levels and enzymes. I am not ready to drink alcohol yet, because I don`t want to risk a bad test result (oh yeah, or my liver). At 14 doses in as of last night, I figure I am about 1/12 there! I am measuring this ride in terms of days, not mgs. I truly believe that within 30 days my skin will be completely clear and virtually oil free. If it takes another 4.5 months to keep it that way for a long time, then I will be a happy guy.
OldLawyer LOL... Talk about hitting the nail on the head. Man I am keeping a close eye on this libido thing. I have never really had to come to terms with the possibility of losing it permanently. I still have a roving eye and my wife is wondering if I am in my second childhood. I want to test it often, which is putting me over my normal schedule. She's telling me "its fine, enough already"..... I am happy to say to all of you potential taners out there that everything still works.

5 Mar 2009
Brand:Sotret
Weight:90Kg = 200lbs
Sex:Male
Age:48
Dosage:20mg once daily

I did my bloodtest day before yesterday and I have my appointment with the Derm in a couple of hours. I am virtually blemish free and oil is no longer a problem. My back had a few blemishes, now gone. I feel relaxed and better than I have in such a long time. Life goes better without the trauma of facial acne and Rosacea. Nose is narrower and no longer throbbing with over active sebaceous glands. I will ask my Derm about the future, cumulative dose plans etc.. I have no real side effects at this point. Slightly dry nostrils, very slight and mild micro flaking of the nose. The flaking is not even noticeable unless I scrubb to hard or wash my face to long. I use cetaphil moisturizer to shave with, apply it to my nose as well and leave it on when I exit the shower. So for now, life is okay. I have taken to having a 4 oz. glass of Cab Sauv once in awhile before bed. I drink more tea than anything and I have cut soda pop almost out of my life. I did my 27th pill last night and slept like a baby. Attacked my wife this morning, just to make sure!!! All is well for now. My hair is not falling out either. More to come..... after the Doc Appt.

Best Wishes
LowTane
OldLawyer, I know how you feel. My life and my attitude have just gotten better because of this highly controversial drug. I am glad for you to be able to go out and have the nagging nusiance of Acne off your back. Right on! Good for you.....

5 Mar 2009
Brand:Sotret
Weight:90Kg = 200lbs
Sex:Male
Age:48
Dosage:20mg once daily


Day 28 or somwhere close:

I went to the Derm and he was happy with the results. He has been working with Accutane with great results for years. He told me its possible to get a complete cure from this therapy. He doesn't however have high hopes that I will get one. He said most people get remissions, but not complete cures. At least in his experience. Now all this guy does at this clinic is Accutane. Thats his primary job description. So, he is the Accutane Doc at this clinic. He shocked me by saying he would like to take the dose lower after this next month of 20mg daily. I thought he would want to go higher. He wants to see how low we can go and still get the job done. He mentioned that most people end up doing Accutane more than once. I got the feeling he thought that if you have to do Accutane more than once it would be better if it were on lower doses. I agreed! In the old days some people were put on insane dosages of 80 to 100 miiligrams daily (and still are) with the idea that higher dosages gave a better shot at a cure. Studies in multiple countries have shown that low, medium and high dosages have resulted in longterm remissions. It affects different people in different ways. My Derm mentioned that he currently had one guy on one pill a week. He didn't say how much. If he goes off that pill he immediately reverts to his pre-acne state. So, to make a long story short, this blog may truly turn into an ultra-low dose blog after next month. I got the feeling we will stop this drug for sure. If I revert to my old state I will need to go back on Antibiotics. After a period of time of an un-specified length my Doc would let me go back on the tane...... So for now I am enjoying the lack of oil and zits. Now mind you I still have scars and some holes in my nose from prior bouts with Acne. But man, do I look a lot better. I just look kinda rugged and tough, yeah, yeah thats it rugged and tough. Well somehow I got a hot wife, so I guess I can survive the look. Well thats all for now folks, pill 28 is on deck in about 6 hours. Stay strong all. Just know this, Accutane works. Low dose might be all you need.

Best Wishes
LowTane
Definately some food for thought, LowTane. My doc tends to be a high doser, and if my body tolerates it, I will go with that. She was much more optimistic about long term results. Common sense (which is dangerous) tells me that relapses in teens with standard acne as opposed to the more vascular rosacia type would be more prone to relapses, taking hormonal activity into account. Moreover, a 10 year remission would leave us with 58 year old skin, which should be less suseptible to the markedly increased oil production. Studies on Rosacia give it a life of 8 to 15 years in most cases. Having been in this boat for 13 years, I question that prediction, but I will admit that over the last 2 years, the episodes of really bad breakouts were decreased to a cyclical one week per month (but as we know, that episode affects appearance for the rest of teh month). Here is something else that you may be interested in: Although my skin was never really blemish free, the rosacea type acne did not really start until after I caught a mild case of the chicken pox from my kids at age 35, and the really bad redness did not start until 5 months ago, which prompted my derm appt. My doctor told me that the bad thing about getting a mild case of the pox as an adult is that mild cases can affect the vascular system. Within a month after recovery from the pox, I developed severe seasonal allergies that would only respond to steroids. Also, my blood pressure rose from 110/70 pre-pox to 170/120 post pox. I am on the mildest dose of BP meds available and that gets it down to 110/70 again, but if I go off it, the BP shoots up again. Keep in mind that although my diet ok but is not the best, I have an affinity for Jack Daniels and I have a high stress job, I exercise regularly, I am not overweight and all other vitals are good. My doc maintains that the pox was the trigger for all of this, including my skin. That is why he put me on antibiotics, which only worked well for a year and did nothing for the oil or the swelling of the nose. With accutane, all of the skin issues are now gone after less than 3 weeks. After I am done with my course, I will definately raise the issue of long term low dose, and if my derm won`t do it, I will go on this again if need be. If that doesn`t work, I`ll try the light show previously discussed in this post. The best part is that there are still options.

Until next week.......all the best.
8 Mar 2009
Brand:Sotret
Weight:90Kg = 200lbs
Sex:Male
Age:48
Dosage:20mg once daily

Day 31:
So, I skipped pill number 30. I have decided that I wish to take the minimum amount of this drug. I will be taking 1 pill every Friday night. I am 100% clear after one month on this drug. I have decided that my sex drive is slightly dampened but functional after the 600mg that was ingested in the first month. I will bump the dosage from there if needed until I arrive at the minimum maintenace level required. I had another all day headache, I skipped a dose and the headache was gone the next day. Since the Derm has mentioned a second round of this drug as a matter of doing Accutane business I am not concerned about getting the drug. I guess this is what I really wanted all along. I decided to take charge of the dosage since I am the one that will have to pay in the long run. My Derm told me he has one patient taking one pill a week which shocked me. He didn't mention it before. Multiple studies address the efficacy of low bi-weekly dosing as an effective way to maintain and acne and Rosacea free state. It will take a lot longer to reach the total cummulative dose this way, but I feel starting low and moving up is better than starting high and moving down. I have found just to many horror stories and they have started to affect me. So, if were gonna go low lets go low and prove something. If I get a remission after an even lower dose regimen and I do it with the minimum amount of this horribly controversial drug the better. If I don't I can always go back and do the the the higher dose regimen if need be.... I probably won't though. Losing my bowel to Crohn's disease (the latest lawsuit by the way, just surf it up) kinda got to me. Until I get over that I am gonna have back off on the dose levels of this drug for mental satisfaction. We all know that Accutane at doses as high as 120mg's a day have been reported. We all know that Accutane clears horrible cases of Acne and changes lives. However, you gotta read the "Ask a Patient database" and read the 393 patient reports on this drug. I have major concerns..... More to come.............

Best Wishes
LowTane
Good to hear from ya Chooch. Thats cool.. Its nice to hear from other low dosers. But I must ask, what was your outcome after your accutane experience. Success, failure? Will you take it again. Did you have a remission etc... it would be cool to hear your story.

Old Lawyer, good to hear from you. You are right, there are side effects listed for every drug. There are lawsuits for multiple drugs on the market. Also, the sampling of horror stories is small in comparison to the number of patients who have prescribed this drug. I had wanted to go with a very low dose all along to feel this drug out. I know that long term antibiotics are no option either. I am torn between long term extremely low dose maintenance accutane and going for the high dose and hoping for a really long remission. I have skipped two pills so far and my headache and dizziness hasn't resurfaced. Could have just been a fluke and had nothing to do with Accutane. My derm is going to lower my dose next month anyway. So, still contemplating my next drug move. I do appreciate your reply. Good Luck...

9 Mar 2009
Brand:Sotret
Weight:90Kg = 200lbs
Sex:Male
Age:48
Dosage:20mg every 4 days.

Day 32:

Well if you have been following along at all you know I am taking liberties with the dosages of this drug. I have backed off on the 20mg daily to 20mg every 4 days. I have no increase in oil yet from the lower dosage. I have felt better on the lower dose. My facial redness (flushed look really) is more normal skin tone now. I am still dry and have very mild flaking. I am 100 percent clear and my pores have shrunk 85%. I am loving this part of this, all things are better. I do believe some of the extremely high dosages doctors have prescribed some patients have really caused some terrible problems. My reading shows that a lot of people get remission but still come full circle back to acne and oil. Many people do this drug several times with long breaks in between. My goal is to go low and stay low and check out my results compared to hopefully someone on higher dosages. Maybe old lawyer will stay around long enough to be that guinea pig. Well all for now......


Best Wishes
LowTane
Hello, I've just started taking a low dose at 20mg a day (10mg twice a day). I'm on my fourth day and have noticed some positive changes in skin texture and oil secretion, but very mild since I haven't been on it that long.

Interestingly enough, I've had issues with my lower lip being dry for a long time without having ever taken this drug before, and I can't even remember when it started so I've experienced zero "new" side effects thus far. My hair started noticeably thinning when I was 25 so I hope it doesn't accelerate it. I shave my head very close to minimize the appearance (not bald close).

I've had acne since I was 14 and it only got worse as I aged (now 30). It started on my face then my back, chest, shoulders, upper arms, some even on my forearms, thighs and occasionally around the calf. I think I pretty much get them where sebaceous glands are most prominent.

I've been able to control it somewhat through diet (low carb, no soda or sweets of any kind) but it's been very persistent for a long time and I'm fed up with it. If I didn't restrict my diet I probably wouldn't have a job right now because my skin would look like a warzone and I'd be too embarrassed to leave the house. In fact, I'm a firm believer that the cause of most skin problems is due to the modern diet of processed foods, sugar and carbohydrates (sugar before digestion). I think my diet over time induced this condition and it may have created a chronic problem that a change in diet might take a very long time to adjust, if at all.

I've passed on some very attractive women throughout my life, to the point where I've hurt people's feelings because I'd take an interest in them but would back off because of my insecurities, so I'm prepared to deal with whatever consequences come from this experiment.
10 Mar 2009
Brand:Sotret
Weight:90Kg = 200lbs
Sex:Male
Age:48
Dosage:20mg every 4 days

Shidoshi, thanks for giving some details. I have dropped my dosage as everyone knows if they are following this board. I am down to 20mg every 4 days. I was going to drop to 1 a week but changed my mind. So right around 2 a week it is.. At first I had no side effects at all, and I am not sure that the things I am experiencing are related to Accutane. Dizziness and balance problems, just slight but noticeable. Also, articulation and short term memory have had some weird lapses. The good that has happened is that I have become 100% clear with 30 pills which equals 600mg in just one month. I have been blown away as to how tortured my sebaceous glands were. Not only has Accutane shrunk my very large pores, it has caused spider veins to disappear as well. I also think a very large part of what I am going through now is directly related to the modern industrial diet. I am trying to change those things now. I have stopped drinking soda pop entirely. I drink more water, I have cut out sugar and almost all alcohol. Caffeine is gone. I am closing in on 50 and I hope that I can reverse years of damage through diet, lifestyle and maybe this drug. Well I may have screwed up the count, but I just took pill thirty. I will keep you posted as time goes on. I know this can get boring at this point. So, I would love to try to get you readers to share your Acne or Rosacea story and find out whether or not you have tried Accutane. Please join and log in an and share your information with us. Lets get this board growing, with almost 3000 views in one month you would think more of ya would stick around and share some information. Please do, it has been extemely helpful to me when individuals share their stories. Well, thats it for tonight.

Best Wishes
LowTane
Lowtane,while i was taking accutane my face was pretty close to normal..
hardly any oil and no breakouts..but once i stopped taking it the oil and
breakouts started coming back...you see with low dose all you are doing
is suppressing everything, once you stop taking it your face will slowly revert back to its old self.... you won't destroy the oil glands on low dose....to
maintan an oil & acne free face you have to stay on the drug long term. Or
take the normal high dose for 6 months and hope it destroys the oil glands.
but since you have slight rosacea i would not take the high dose because
that would push you into full blown rosacea and you don't want that..or
you can scrape the drug all together and look into photodynamic laser..
my advice to you is to go as low as you can...and if you have no side effects
just keep taking it...i am thinking about trying it again...maybe see what i can
get from 20mg a week...not sure though...its a love, hate relationship i have
with this drug.
good luck.
11 Mar 2009
Brand:Sotret
Weight:90Kg = 200lbs
Sex:Male
Age:48
Dosage:20mg every 4 days

Chooch, this low dose study done in Israel came up with some significant remission rates on low dose Accutane. Also, I have found many individuals who have taken high dose had their acne return. So, I am not sure what to make of it. Many doctors in other countries think the Americans prescribe too high of doses. Many researchers believe that it is the total cumulative does that counts. Low dose avoids the chemotherapy burn your oil glands to a cinder and hurt the rest of your body approach. The following study was conducted over a 4 year period. Read this and see what you think...........

To everyone else, I can vailidate one of Chooche's observations. So far with a pill every 4 days no oil, no acne and no real problems.

I removed this article to be in compliance with board rules: Google the following to find it.....

Israel: Low-Dose Isotretinoin for Acne Vulgaris
12 Mar 2009
Brand:Sotret
Weight:90Kg = 200lbs
Sex:Male
Age:48
Dosage:20mg every 4 days

Chooch, heres the part I am talking about:

A total of 617 patients completed the study. In group 95% of patients achieved considerable improvement or complete remission of their acne;

Somewhere in that 95% were low dose Accutane users who acheived complete remission.

Where low dose is concerned my thinking is that the lower doses cause less damage to vital systems. I could tolerate a minute amount of strychnine once a week for a long time. However, a full cup would kill me instantly. I know that analogy stinks but its all I could come up with on short notice. Since the actual mechanism that makes Accutane effective is unknown, I believe it warrants extreme caution. I know there are quite a few individuals out there wishing they had never seen or heard of this drug. Many other countries are reporting responsible long term usage on much lower doses. I believe it is prudent and wise to re-think western methods. Many blogs report high dosage acne relapses. If someone starts on low dose, they can always later on try a higher dosage. At least they had time to feel out the drug and see if they can gain complete remission without as high a risk. I only posted two studies, there are more from Germany, UK, Turkey, Israel, Sweden etc... They are all advocating therapies that involve lower dosages, for very good reason I believe. So, for me, I feel much better trying the lower dose regimen before committing to a higher dose regimen. I certainly wouldn't recommend this drug to anyone without caution. I am 100 percent acne free on my entire body, with extremely minimal side effects thus far. I am maintaing that condition so far on 20mg's every 4 days. I bet based on how my body feels, that I could do it on even less. I intend to try and prove that point in the very near future. Dr. Plewigs study suggest some individuals maintain an acne free state with as little as 2.5mg's twice a week. To be fair, it is working for people with mild to moderat acne, I don't see a lot of low dose reports for really bad cystic acne. This drug completely cleard up my nasty oil acne riddled skin in one month. I am blown away. I had to take in 4 different studies which I printed out and show my Derm before he settled down to the idea of low dose. Now he seems to be fully on board with the idea. We could do American acne sufferers a big favor if we would all do the same thing. Educate them thar Doctors as to what the foreigners are up to with this controversial drug called Acctutane. Some Doc's may listen.

Well, enough conjecture for tonight.

Ps. I would rather take this drug for 8 years safely and remain acne free, than taking high dose for 6 months and possibly suffering from side effects for the rest of my life. However there are no real long term studies on low dose Accutane either. It could be just as risky.

Best Wishes
LowTane
I'm on day 8 with no additional side effects (20mg per day). I've gotten some bumps on my chest and back but those were my most problematic area. All around, my skin is clearing up and my oil production is down.

I'll probably need to get a facial or something because I've got a lot of clogged pores in my T-zone that are very stubborn and I guess it doesn't help that I developed a habit of trying to squeeze them. I've probably made the problem worse not realizing it. Other than that everything is fine, no sexual problems, no headaches, just a dry lower lip that I had for a long time prior to taking Accutane. I find it's better if I don't wash my face with any products, I just rinse it off with water.

I think you've mentioned this Lowtane, but I also think most people will greatly benefit from eating a healthy diet in addition to this treatment. Diet was the only thing that gave me some relief before taking Accutane. I've never even taken antibiotics. You have to remember that acne isn't just some hormonal disorder, it's a symptom, almost like a warning sign that something isn't right and people need to heed this warning and not just "suppress" the symptoms. There's a reason why millions suffer from this disease in mostly developed countries.
14 Mar 2009
Brand:Sotret
Weight:90Kg = 200lbs
Sex:Male
Age:48
Dosage:20mg every 4 days

Well Chooch, I am only guessing here...but I don't think lifting weights will increase testosterone levels much. But what the hell, it couldn't hurt to try it out. Now the supplements, thats not a bad idea. Hopefully whatever you choose will not contraindicate with the Accutane. I am able to get around the damped libido effect with an adjusted mental attitude.

Shidoshi, you couldn't be more correct about helping Accutane therapy out. The modern industrial diet has provided us with many new diseases. One look at nature and we can see that proper diet and exercise keeps the animal kingdom acne free. I have cut out soda pop entirely. I have cut processed sugar to the absolute minimum. We are held captive by the shelves at Safeway. Unless you can grow your own food and hunt regularly you are basically screwed where sodium, sugar, cholesterol and fat are concerned. On your pores, mine have been giving up little hard spicules that come out when washing or just gentle rubbing. You may be shocked at just how tight your pores will get. Unless you have taken this drug before. I can't remember if it was you that posted this is your second time on Accutane.

Well good luck all, time for work unfortunately. I will keep plugging away with the lower dose regimen. I intend to go so low my Acne returns. I am flirting with the idea of longterm micro-dose. If I can stay clear on 2mg twice a week like Dr. Plewig's study suggest, I might try it. I have already noticed that 20mg every 4 days instead of every day has improved my libido.

Side effects minimal, definite slight damping of the sex drive. Extemely mild headach once in a while. Lower lip slightly dry. Thats it as far as I can tell...

Still 100% clear, with oil at an absolute minimum with just over 600mgs and only 40 days in........ unbelievable.

Best Wishes
LowTane
19 Mar 2009
Brand:Sotret
Weight:90Kg = 200lbs
Sex:Male
Age:48
Dosage:20mg every 7 days

Well, not much to say here. I am half way through the second month of my Accutane therapy. A total of 660mgs of Accutane have been consumed. As you know the title of this thread is "LowDose" Accutane. What is considered low dose? Anything less than the common standard of .5 to 1 milligram of Accutane for every Kilogram of body weight. You will find that researchers consider the total cummulative dose the key factor in remission rates. So, you would end up taking just as much Accutane as a high doser. It would just take a longer therapy to reach the total cummulative dose. So, whats the difference? Some Doctors believe that higher doses result in better and longer remission rates. There are many reports of successful remission at higher dosages. Recently reports on low dose studies have also shown good remission rates for low dosers. Some doctors in other countries are using low doses bi-weekly to sustain remission in some patients. These doctors have reported that monthly blood tests are not required at these low dosages. So, this is actually where I wish to end up if I don't get a remission. Start low, stay low and try to avoid any longterm side effects at all costs. Now it should be noted I have found no studies on longterm low dose Accutane therapies. Short term studies exist. Therein lies the problem. Long term lowdose could be as much a risk as short term high dose. All of these assertions should be taken with a grain of websalt. Ask lots of questions, get more than one doctor's opinion if possible. Try to ignore threads like this one and form your own opinions based on professional resources only. I paid to get the scientific journal access for Rosacea, Acne and the effects of low dose Accutane. I am convince it is right for me, with my obsessive mindset and all. How is it working so far? Wow! My life has improved immensely. But, inspite of it all. There are a multitude of people suing and winning over Accutane longterm side effects. It is easy to find what seems to be normal average everyday people reporting on different blogs horrific experiences with this drug. I can't ignore that entirely, I just can't. It is anecdotal and non-professional reporting to say the least. I still think there is some merit in paying heed to these stories. It is also fair to say that many high dosers report the return of there acne. Yet, it is also fair to say that many high dosers report long multi-year remissions with no long term side effects. It is also my speculation that successful Accutane users aren't as likely to report. They are to busy having fun. With 12,000,000 users world wide reported it seems that the percentage of bad experiences might be low. So, in the end, I know nothing other than what my own research has produced in the way of a perception of Accutane. I just know this, if engaging in certain behavior can result in a permanent long term outcome, I really want to dot my eyes and cross my tees before leaping into a therapy. My experience with doctors has shown me that it is okay to second guess them. This is where the "get a second opinion" cliche originated from. People second guessing their doctor. Please read up on possible longterm side effects. It is not a fantasy, many of these effects are listed right on the warning label in my very own Accutane prescription box. I am just a regular person trying to deal with a mentally devasting physical condition. Acutally two conditions. I have both Rosacea and Acne, and because of Accutane you would never know it. It has amazed me to no end......

I wish you the best...

LowTane
19 Mar 2009
Brand:Sotret
Weight:90Kg = 200lbs
Sex:Male
Age:48
Dosage:20mg every 7 days

I am not sure who is following this diatribe, but it is getting a bit thin on content. I will start posting weekly. Its getting too repetitive, all I can say is every day I am still 100% clear. I think this will get interesting again when I have terminated my low dose therapy. I leave you with this summary:

I started taking what is considered low dose Accutane for my size. This was made possible after I lobbied my Dermatologist with no less than 5 different studies on low dose Accutane from several different countries. After I dropped off the material I got a call and he set the dosage along the lines of the average low dose reported in the aforementioned studies. The first month I took 20mgs daily. I had immediate results. I had been given an antibiotic that doesn't contraindicate with Accutane in case the intial breakout was bad. He didn't want to do this at first, but it turns out I didn't need it. Accutane went to work gangbusters. With this dosage I had only some mild side effects. Slightly dampened libido, dry lower lip and an occasional mild headache. After the first month I was 100% clear. I then dropped my dosage to 20mg every 4 days. I remained clear...I then dropped it to 20mg every 7 days. I am still remaining clear at this dosage. This is where I am now.
I will continue my low dose experiment. When I have something to report I will certainly post it. Until then, I can only say you might consider low dosage if you have moderate or maybe even severe acne. You might consider low dosage if you have major oil problems. Hell you might consider low dosage if you have a hang nail......I have to say it has been a miracle for me so far. I fear the high dosage idea and will probably never ever opt for it. Doesn't mean that high dosage hasn't worked for people. It has.. I just believe that it makes permanent side effects even more possible. These are my own personal feelings, like I said, a grain of salt. I know nothing about this drug in all reality. I am just operating on my personal instincts. So, my observations only serve one purpose. They are cathartic for me. It may however help someone to hear someone else's story. Please read read read and get lots of doctor's opinions before saturating your body with this controversial miracle drug called Accutane.

I wish everyone the best.
LowTane
Thanks LowTane,

Thing is, I've never taken accutane before so this is new to me, but I'm just not sure about the underlying cause. I'm thinking about taking a 2 week break from accutane and sex. If it were just diminished "interest" in sex I could probably push on, but this whole lack of orgasm thing is scaring me a little.

I think accutane has some kind of effect on sex hormones because of how it reduces oil production, which started for me after I went through puberty along with a number of things including acne, dandruff, allergies, etc.

I think I'll take a week to 2 week break and regroup to see if this normalizes, if it does I'll probably go back to the routine as I believe what you stated about the "cumulative" dose.

Accutane is the only thing that had a significant effect on clearing my pores and I'd hate to have to stop it completely.
Shidoshi, I slowed down to 20 mg a week for awhile. I felt better and my skin's progress didn't seem to change at all. I am now back to the 20mg daily. If I have headaches and libido problems I will probably back off again on the dosage. I believe that doing the least amount of harm while building on the total cumulative dose is the way to go. If I don't get a remission after all of this I may try another round. What the dosage will be I have no idea. I am hoping that life style changes coupled with the Accutane therapy will give me a new acne status quo. If I have a relapse I will go back on antibiotics until my rest period is up. I will then try Accutane again. The last possible idea is exteme low dose long term. I have thought about this quite a bit. Some doctors are doing this with some patients. It violates the FDA's rules for administering this drug. I guess they are williig to take this chance with their licenses. I am at a point now where I can't tell I am even taking this drug. The lack of oil and the smallest pores I have had in 12 years are what remind me that his drug is still present in my system.....

Best of Luck All
LowTane
LowTane, Its nice to hear some positive results with low dose accutane. Im kind of in the same boat as you are. Im 22 with mild acne and really oily skin. Ive tried all the anti biotics/topicals and even ran a course of accutane at 80mg a day for 5 months back when i was 15 when i had it severe. Worked great and was clear all the way up to 07. Now i have the stubborn mild breakouts again that wont go away. I have been using the regimen sense i started breaking out again back in early 2007. It has been working ok but not enough and i really dont want to keep putting benzoyl peroxide on my face for the next 10-20 years. So i decided to go on low dose accutane at 20mg a day sense im not severe and dont want all those nasty side effects i got with the really high dose. Right now im on day 11 and so far so good. Maybe a little bit of an initial breakout but not bad and hoping it wont get worse. Im planning on running this dose for 8-10 months and then maybe cutting it back to 10 mg a day for 2-4 months or maybe even less. These studies of people running ultra low dose has me very interested as i might be a canidate if this second treatment does not allow complete remission. I will keep in touch with my progress.
I forgot one thing, Rosaceans, I have not had one flush in over a month. This drug has curtailed all Rosacea symptoms. This includes food and drink choices. I know this is the Acne board, but if you stumbled here, you should know I have both on my nose. Accutane has controlled both maladies.

Best Wishes
LowTane
Hello All

Well I am back from the Derm. We will lower my dosage to 10mgs daily. All blood tests were baseline normal. I am not having major side effects at 20mg. It will be interesting to see if the lower dose will still maintain the status quo of the oil and acne manifestations. To any Rosaceans reading this, you should know that not only has the Rosacea subsided, I am able to eat and drink trigger foods with wild abandon. I have had no flushes and my face maintains an even tone and color with a mildly flushed appearance that resembles minimum time in the sun. I am going to experiment with low frequency red light to see if I can promote some collagen. It seems as if Accutane has stimulated something in the way of collagen on its own. Scars seem to fill in some, this, along with major pore closing. Its an amazing drug. If you have moderate acne and major oil you could consider trying to educate your Derm to the idea of off label low dose Accutane therapy. It will change your life. All the while keeping in mind that side effects have been reported at all dosing levels. I believe this drug can be extemely dangerous to different individuals at all dosage levels. I wish you all the best.

LowTane
Hello All :p

I noticed this thread has now passed 8000 views. I was thinking about this today. I don't know how many return to this thread more than once, but my hopes are that viewers will spread the news to their prospective doctors about low dose therapy studies conducted in other countries. I am not a scientist, I am the lab rat. When I look for low dose Accutane information I get results from Italy, Israel, Iran, Turkey, Sweden, Germany etc.. So far I have not found any major studies conducted in the United States. On my last visit to my Derm he lowered the dosage to 10 milligrams a day, to do that he gave me a prescription for 20 milligrams a day 10mg twice a day. He told me to take just one 10mg pill a day. He did this to cover his butt, because he was "off label" tinkering with the dosage of this amazing controversial drug. I was told that he attends conferences annually and low dose Accutane therapies were not on the agenda. Now, granted this is only one doc, but his position seems to echo my research for American drug therapy choices where Accutane is concerned. No real [B][I]long term [/I][/B]studies have been done where low dose Accutane is concerned. The idea is that some docs believe that it is the total cummulative dose per kilogram of body weight that counts. This means you would be on the drug a lot longer than someone on a higher dose. The target number seems to come from earlier studies. It is 120mg per kilogram of body weight. I am 90kg (200lbs) that means that my total cummulative dose would equal 10800 milligrams. At 10mg a day it would take 36 months to reach that goal. Now there really aren't any studies supporting this type of therapy. So what it comes down to is that doctors who opt for this low dose regimen are in violation of the FDA approved therapy. So, the doctors have a little leeway but can't get crazy without being in violation of the approved "on label" therapy. My ignorant, layperson informal opinion is derived from a simple analogy. What good is it if the cure kills the patient. The horrible side effects, bloody noses, depression, suicidal tendancies, triglyceride elevations, cholesterol elevations, bone and joint disorders etc.. are minmized with the lower dose regimen. With this caveat, maybe???????? Because who really knows. Long term low dose studies are not very abundant. I just think it would suck if this miracle drug that changed my life so drastically to the positive in such an amazingly short time was removed from the market. Or worse yet, individuals pass on trying this drug due to all out fear. I have virtually no side effects, and a perfectly clear face now. I am thrilled to death. If you are in America, approach your Derm and ask them about the studies conducted in other countries that criticize high dose accutane therapies. Tell them you know of formal studies that suggest that low dose therapies are just as effective as high dose in some patients. See what they say! My Derm decided to play ball. Now, I don't know if I will get a remission when I stop this drug. I will continue to post even after I stop Accutane to let people know what happened to at least one person on low dose Accutane therapy. At the very least, I am super glad to be off antibiotics. I am glad to get this amazing break from my tortured, swollen, oily, acne ridden face. My job, my sex life, my attitude and my fun factor have all improved a million percent. I am in short, enjoying life again for the first time in years.

Disclaimer: Accutane can be a very dangerous drug for some people. I believe this with all my heart. I don't wish to talk anyone into using this drug. Do your homework, consult multiple doctors. And never, ever self medicate off the internet. To many items need monitoring with monthly blood tests to take a risk self medicating. Read about all the possible side effects this drug can cause. At any dose this drug causes birth defects. Remember, what works for one person may be a catastrophe for another.

Luck

LowTane
Happy it is working for you too, LT. Derm said to me that despite the oil and recurring nose cysts I was "not all that bad compared to teens with full facial acne." I beg to differ, but she is the doc and sees more cases that she calls stubborn. Bottom line is that nothing else worked, ever...meaning for decades.
The only "depressing" thoughts I have are related to post treatment regression. If that happens, I will be back to the derm to discuss low dose maintenance. I simply cannot go back to the way I was 8 weeks ago. It is so great to wake up and not have to look in the mirror before I do anything else, and to go out without having to do a status check every hour. This drug has changed my life in a very positive way.
In summary:

The purpose of this board was to explore the results of using low dose Accutane (Isotretinoin) over a longer period of time than normal therapies with high doses used in a shorter period of time. After becoming desparate with Sebaceous Hyperplasia (enlarged over active oil glands) and mild Rosacea I began reseaching the web heavily and discovered some studies in foreign countries that showed the efficacy of lower doses of Accutane. Why go with lower dosages? To minimize side effects, long term and short term. The end result desired? To go into long term remission for Acne and Sebaceous Hyperplasia. Here is where the debate begins. Some studies have shown significant remission rates with lower dosages. The United States is furthest behind in this type of therapy. Just talk to your Dermatologist and see..... The rule of thumb in this country is "higher dosages = longer remissions and/or possible cures". Individuals have reported the return of their acne with high and low dosages. Other individuals have reported cures and long term remissions with both high and low dosages. We have all heard time and time again that everybody is different. Even though we are of the same species. Its true, drugs seem to effect people differently. I am opting for the lowest dose possible and still maintain an acne oil and rosacea free face. So far I am running perfect, first on 20mg a day and now 10mg a day. I will try to lower the dosage again upon my next appointment. My American Derm is suprised and mildly shocked at the overwhelming positive effect low dosages are having on me. I am 200 pounds. I have referenced links to different studies on Accutane therapy at pubmed and medscape. Talk to your Derm and show them the studies if they are not already enlightend to low dose Isotretinoin therapies. Best of luck....

PS. No matter how I try to explain the positive effect this drug has had on my life it will be understated. I am ecstatic. I have regained my life for the first time in years. I say this knowing that the longterm problems some individuals talk about where this drug is concerned could still be waiting for me somewhere up around the bend.

LT

Disclaimer: Accutane can be a very dangerous drug for some people. I believe this with all my heart. I don't wish to talk anyone into using this drug. Do your homework, consult multiple doctors. And never, ever self medicate off the internet. To many items need monitoring with monthly blood tests to take a risk self medicating. Read about all the possible side effects this drug can cause. At any dose this drug causes birth defects. Remember, what works for one person may be a catastrophe for another.
Hello!

A study from the United Kingdom, not really a low dose study. However it addresses the significance of total cumulative dosage and relapse of acne over a 10 year period.

http://www.ncbi.nlm.nih.gov/pubmed/8286227?ordinalpos=4&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum
Hello!

Might as well put Saudi Arabia in with their study. The significance of this study is that 90+% of the patients had adverse effects from the traditional dosage of .6mg to .75mg / per kilogram of body weight. Even though the patient's acne was cured.

http://www.ncbi.nlm.nih.gov/pubmed/8655243?ordinalpos=3&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum
Hey Shidoshi.... good ta hear from ya..

Well a short report, 200lb man taking 10mgs of Isotretinoin (Accutane) daily remains one hundred percent acne, rosacea and oil free. I have no side effects at this point and can't even tell I am taking this drug other than the positive effects described. Like I have said before, this thread will become more interesting once I stop taking this drug. I hope visitors have cut and pasted the links provided to read some of the abstracts published by ligitimate research professionals in regard to Isotretinoin. Many types of drug therapies have been tried for Accutane. Hopefully this type of information may provide different individuals with alternate methodologies over the American traditional high dosage approach. Accutane has stopped 3 major negative physiological aspects of my life. All the while in the back of my mind, I still have some worry in regard to the long term outcomes. I have noticed the lower the dose the better I feel mentally and physically. Some dizzy euphoric episodes have dissappeared. 10mgs a day is 1/9th of a traditional high dose of this drug for my body weight. So the question still remains, will lower dose over a longer period of time be as effective for remission as a higher dose over a shorter period of time? That is the question. We shall see...............

LowTane
OL, that is a fair question. The truth is the mini-putt course down the road has been my nemesis for quite some time now. Now, I know that some people think 88, big deal! Well, I started at 125 9 months ago, (yes for 18 holes)....... I have shaved 37 strokes off my game. Thats an average of 4 strokes a month. I am dreaming of breaking 80 as I write this little blurb. I am playing 6500 yard courses with decent ratings. I walk these courses for the exercise.. the way to tie this story into Accutane once again is to say, 10mgs a day and sunscreen made it all possible. Still clear of all acne and rosacea symptoms. Am I slowly killing myself or pointing myself in a direction that will be fraught with problems down the road? Dunno....! We shall see. I will not give this drug a 100 percent thumbs up until enough time has gone by to fairly assess results.

Best wishes
200lb 10mg daily
Rosacea, acne and oil free..........no noticeable side effects.

LowTane
Hello!

Here is a quick summary as to the intent and direction of this thread.

49 Year Old Male
2 months of 20mg Accutane daily, reduced to 10mg daily.
Total therapy is right at 4 months.
Symptoms: Acne Vulgaris, Sebaceous Hyperplasia (massive oil) and Rosacea.
Accutane put a halt to all symptoms within the first month.
No depression, (actually the opposite) I am euphoric about the results.
Sex drive, temporary setback but settled back to normal within a month and a half.
Side effects at this point as far as I can tell are Zero.

I have posted links to multiple studies in regard to Accutane dosages. My philosophy is not my own. I got the idea for low dose therapy from the aforementioned studies. The idea is to stay on it longer than short term high dosage conventional therapies advocate. The consensus amongst the studies are that total cummulative dose is the important factor not the duration or dosage level. Not all Derms agree on this point. I am trying to prove the theory for at least one human being. I love what this drug has done for my life. Words do not do justice to the effect this has had on my job, my marriage and my mental well being.

Disclaimer: This drug can be extremely counter productive to some individuals in my humble opinion. I am a complete layman with no formal training in area pharmacology. So its obvious my opinon means little. I can only report my results.

I have an appointment on the 7th, I will report anything new. I hope that some readers will find the same satisfaction with this treatment. Print the studies linked and show your Derm. Try low dose before high dose. Most doctors won't object to this before urging you to higher dosages. I refuse the high dose therapy, I will never concede to a higher dose regimen. Thats just me...........

Best Wishes
LowTane
Hi all....

I am back from the Dermatologist and the blood tests are the same as always. Cholesterol and Triglycerides are normal, for me anyway. We are going to take the dosage lower. I will now skip dose the 10mg's a day to 1 capsule every other day. We talked about long term outcomes and total cumulative dosages. I would have to be on Accutane for a long time at this dosage to hit the often mentioned "total cumulative dosage" of 120mg's per kilogram of body weight. At these dosages I can see he is considering a possible maintenance dosage. He mentioned he has a guy that has been on 40mg's once a week for 7 years. Which is equal to about 5.5mg's a day. Which is around 1/15th the normal dosage of 80mg's daily for a short term therapy. So it would take 15 times as long as the normal regimen of about 4 months. So that is about 60 months, or 5 years. What does it all mean? I am not sure. I think that the more I read I find some doctors are starting to see alternative therapies as a possible course of action with Accutane. When you think about it, its possible that some individuals could get maintenance dosage levels long enough for their body to actually change on its own to an acne free state. Who knows? I can tell you this, the low dosage wouldn't even be noticeable if it weren't for the lack of zits, oil and rosacea. I am much happier at this lower dosage than I was on the 20mg's. Even though the 20mg's wasn't that bad. Still, I had some weird feelings and libido problems on 20mg's that I wasn't sure that Accutane had caused. However, on 10mg's those symptoms are gone.

Well thats about all folks, it's life changing. It's controversial and maybe even dangerous. I believe that low dosage this drug may help some people but not others. I believe some people could have problems with this drug at any dosage. I will continue to share what I can as it comes up. Read all of the studies from the links provided in multiple posts. When you goto pubmed and medscape, help me and others out here. Re-post those studies. Make sure you only post health board approved site links. Pubmed and Medscape are government run and I was told okay to link to.....

Best Wishes
LowTane
Hello all....

Just thought I would check in.... Not sure who is viewing if anyone. A quick update:

200lb
49 year old male
Sebaceous Hyperplasia
Rosacea
Acne Vulgaris
Started on 20mg Accutane daily for two months or so..
Switched to 20mg every other day for a month
Currently 10mg every other day...


All symptoms are gone!

This board has reached a statuse quo. There are no new items to report as of now other than this fact. The 10mg a day therapy seems to allow me to have normal sun exposure. I was out doing yard work on a cloudless day for 5 hours. No problems. So..continue to check back to see when the Accutane therapy ends. It will then be important to post what happens post therapy. Make sure you go back into the posts and use the Medscape and Pubmed link info to read up on different Accutane therapies taking place in different countries. This information may help sway your dermatologist into trying low dosage therapies before higher dosage therapies are employed.

Best Wishes
LowTane
Still here............

I am taking 10mg of Accutane every 3 to 4 days now. I still have no sign of oil, acne or rosacea. I have consumed alcohol on occasion and noticed that veins seem to return in my nose. Pores are still shrunken in appearance. Within the next couple of months I expect to go off this drug and see what happens. More to come............. Hey OL, hope all is well.

LowTane
Good to hear from ya OL!


Summarization:

This thread started with two main characters. Lowtane (myself) and Old Lawyer. Lowtane started on 20mg daily of Accutane while OL went with a more traditional dosage of 40mgs daily. LowTane continued to lower his dose slowly overtime while Old Lawyer had his raised over time. Two different therapies for some of the same type conditions. In effect Sebaceous Hyperplasia (massive oil) and resulting acne. LowTane had the lovely addition of Papular Rosacea. So far both candidates have had a complete remission of all symptoms from their ailments. The thread was fairly exciting at first with the onset of results. Once the Acne, Rosacea and oil disappeared the thread became a little dull with nothing new to report. So, I posted multiple links throughout the thread pointing to studies from two board accepted sites. Pubmed and Medscape. The studies are wide ranging geographically and ideologically. Many countries have been more pioneering in the approach to their usage of this horribly controversial drug. I used these studies to convince my Dermatologist to try a low dosage regimen. He bought in and here I am. With my dosage sinking ever lower the drug remains effective and I have zero side effects. I will however be on this drug longer than Old Lawyer. The one main idea of Isotretinoin therapy revolves around total cummulative dosage. This is the total ingested milligrams per kilogram of body weight. Because of this I will be on the drug longer than Old Lawyer. The total most agreed upon in the medical community seems to be around 120mg per Kilogram of body weight. Convert your body weight to kilograms and multiply it by 120mg and you will get the correct total. What everyone should know at this point is this: I believe this drug has caused some individuals severe health problems. Even after they have stopped taking it. I also believe some people have taken it with no problems at all. Millions have taken this drug. There are not millions of lawsuits. Accutane is extemely effective period. At what cost to each individual is the subject of much debate. I am a chicken, I have opted for low dose simply from fear. Also, if I were you I would not self medicate. You must have the blood tests to keep an eye on this drugs affect upon your cholesterol, triglycerides and liver enzymes. You are risking a heart attack or destroyed liver without knowing the facts only a regular blood test can provide. My life has been changed for the better. At what long term cost if any is unknown at this time. I believe old lawyer and I will make this thread interesting again when we cease our therapies. I don't want to tell a single person to take this possibly insidious drug, yet I want to kiss a chemist every time I meet one. What incredible results! My life has been changed. Just remember, what works for one person can be a devastating failure for another. I would suggest the low dose approach initially just to see if your body can deal. Some doctors online report using the low dose approach before going to higher dosages. I love the low dose approach. Even if I had to stay on this drug for life, I wouldn't mind if the dosage was only 10mgs once a week. I am now doing 10mg every 3 to 4 days. At this dosage I am not even sun sensitive. Rosacea is zero, oil is gone. No zits....yeeehawwwww!

Best wishes
LowTane
Thanks for the report Old Lawyer. We will be interested in your next blood test results.

Its me LowTane reporting back in.... I am sorry I don't post as often, but I have nothing really new to report. I have moved my dose considerably lower with my Derm's blessing. I am on 10mg one day and then off two full days and then 10mg's again. I will cut that back to 10mgs off 3 days and then 10mgs again. My goal is to get to 10mgs once a week and still hold the results. Again, Accutane has stopped my Rosacea and my Acne Vulgaris in their tracks period end of story. Any of you out there with these maladies have my sympathy. I still believe in the Low Dose approach. I think the less of this drug the better. I hope that OL will continue to report after his therapy is complete. I will also be pulled of this drug eventually. When this happens I will continue to report as well. Till then, search the links provided in this thread and arm yourself with information to approach your Derm with..... I wish you all the best. Accutane has returned my life to me, I am very greatful for this drug.

Best Wishes
LowTane:p
[QUOTE=exxon;4020684]I've read all your posts. Thank you for taking the time to post. I too have rosacea and severe oil problems. I've never seen a person with skin as oily as mine. I've considered taking accutane but have been afraid to do so. Controlling oil with accutane is considered off label use and I'm not sure why the drug company that makes accutane hasn't conducted clinical trails for this use. I will continue reading your posts and if you continue to be in remission after stopping the drug, I will probably take it. Again thank you so much for posting.[/QUOTE]

Accutane does these things

1. It dramatically reduces the size of the skin's oil glands (35%-58%) and even more dramatically reduces the amount of oil the skin produces (around 80%).

2. Acne bacteria (P. acnes) live in skin oil. Since oil is so dramatically reduced, so is the amount of acne bacteria in the skin.

3. It also slows down how fast the skin produces skin cells inside the pore, which helps pores from becoming clogged in the first place.

4. It has anti-inflammatory properties.


Basically, I know it sucks, but you're not going to get prescribed accutane just for oily skin. Accutane is after all other methods have failed. But IMO, accutane is a cure and/or more convenient way to treat acne problems. ESP lower dose now being more popular.
I'm on 35/150th day (20mg/day).

Blood test results continue to come back fine. I was put on Accutane with the request of other doctors who had me on meds that side effects were Acne. I always had acne, Every day I had from 2 to 5 noticeable zits on my face. Large pores, black heads, more Oily than the day before. But the meds made my breakouts more often and severe. I had big zits on my neck below with my bread grew. I'm 22 years old. I'm just so happy to be on accutane. The acne around my forehead and sideburns are no longer present, if something comes up, it goes away within a couple of days.

I take accutane with 5 fish oil gels at any meal during the day.


The noticeable effects are big red lips, they are not that dry, but it looks like a clown's lips to put in a better perspective.
Yeah, I would say that we are controlling the oil and the Rosacea. I would also say that at this microdose with monthly blood tests that my Doc is comfortable that he is doing no harm. We will probably take a break sometime and when the oil returns go back to what works. He is fully informed as to what I am doing. Some people have been able to controll oil with vitamin A. Accutane is a substance "isotretinoin" that we have in our bodies naturally. I am not concerned about long term usage at these levels. I am getting burned out on the blood tests though. However my Doc is not comfortable with his liability without them... I am trying to talk him into every two months for blood tests. So far no go...... I totally understand the pools of oil coming off your face. My face use to look the same way. Add the acne and the Rosacea into the mix and I looked bad. I am very happy with what Accutane has done for me.

Best Wishes
LT
Hi! I have read all of your posts (thank you for doing this!)
I have mild-moderate acne and rosacea, and though not an extreme case, my skin condition is fairly resistant to all acne/rosacea treatments. - and despite over a decade of trying to eradicate my acne, it still persists.
I started accutane today - after much deliberation - I am 130 lbs, 24 year old female, taking 10 mg a day to begin at breakfast. Admittedly, I was (still am...) extremely nervous to take the pill! - even at such a low dose. I was wondering if I could share my experience on this thread, as the days progress? I probably won't post everyday, but I think that it would help me to be able to communicate freely with someone who is doing the same thing as me.
Also - with all your extensive research, did you find anything relating to possible brain alterations and low dose accutane? Or, even at higher doses, in general?

Thank you :)
Old Lawyer, very interesting indeed. I am sure we will all be interested to have you post regularly if you will after you have completed your therapy. I know I am....... I am really interested in your Derms comments on maintenance dosage levels. My Doc just suggested that was all we were doing with my therapy. He doesn't seem to think there will be any remission. I will stop this drug some day and I will still get to see if the low dosage regimen had any remission outcomes. Just to remind readers, I have been on 20mg daily and tapered to 10mg 1 day on and two days off. I have no acne or rosacea symptoms period. I do have oil and you can blot it, but it is minimal.... I will also report my results post accutane whenever that happens. I really think there is a place for low dosage maintenance for oily people.

Best

LT
Recent study:

Low Dose Accutane for Moderate Acne

http://www.ncbi.nlm.nih.gov/pubmed/19143903?ordinalpos=5&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum


Just cut and paste..................

I can find these popping up regularly on pubmed. Many doctors seem to be trying the lowdose approach. However, its countries other than the USA that seem to be leading the charge. Remember, arm yourself with information before approaching your dermatologist. Low dose Accutane has cleared my Rosacea and Acne. I am sticking to my story.

LT
If you are new to this board you should know that it is primarily about low dose Accutane for the treatment of Rosacea and Acne Vulgaris. I have posted many links to Pubmed where low dose and alternative Accutane therapy studies can be found from multiple countries. These studies have beem conducted by legitimate Dermatologists from around the world. Sadly the USA seems to be behind the curve on the low dose approach. I am currently on 10mgs 1 day on and 3 days off. I am perfectly clear and have no Rosacea flare-ups. I haven't had a single pimple in 5 months. If you create a portfoilo of studies and show them to your Derm you may get cooperation. I did. Remember that is a violation of FDA policies and is considered off label treatment. It may be that your dermatologist is not enough of a rebel to shoulder the perceived liabilities that could occur. Even though you are being administered less of the drug. What harm could that cause? I have no idea, less seems safer. So, good luck and I wish you all clear skin.

LT
The cause for the dosage changes have to do with the negotiation on dosages that my Derm and I participated in........... I kept pushing lower and he would push a little higher. I am now in the process of considering 10mg once a week. I haven't taken a pill for 5 days now. I am looking for the absolute minimum dosage that keeps Rosacea and Acne Vulgaris at bay......



LT
Hello!

Summary: Low Dose Accutane for Acne Vulgaris and Rosacea

I am a 49 year old 200lb male and I have been on what is considered (for my body weight anyway) low dose Accutane since February of 2009. I have dual maladies, I am blessed with Rosacea and Acne Vulgaris. Due to the nature of my job I am constantly under fluorescent lights and speaking in front of groups of people. Both Rosacea and Acne look even more hideous under these type of lights. My appearance was affecting my job in a most profound negative manner. I had been aware of Accutane for 20 years, or since its inception into the Acne family of drugs worldwide. I always feared Accutane from day one. One day in desperation I once again began researching this controversial drug and found a study done in Israel on low dose therapy. Hmmmmm!!! I said. I decided I had to try this approach.

I began this treatement in Feb 2009. 20mg daily was prescribed only after convincing my Dermatologist with a barrage of worldwide studies in the efficacy of low dose therapies for certain Acne and Rosacea conditions. Please consult Pubmed and Medscape for all the ammunition you will need to create a portfolio for your Dermatologist. Be prepared for apathy from your Derm over internet research. Make sure you let them know that you have legitimate studies from government reporting sites done by actual researchers. The USA is woefully behind in the low dose approach with this drug. So much so that it is considered off label treatment when other than the prescribed high dose regimens are applied. Have sympathy for your Doc, they want to keep their licenses.

Anyways, I started on a higher dose than I wanted to because my Derm was a little skeptical. I gradually reduced that dosage over time and began to just tell him how much I was taking and he would look at the results and tell me to stay at that dosage for X amount of days. I would ignore him and lower the dosage again. Next appointment same routine. I am now trying just 10mg every saturday. I will let you know how that works for me.

My treatment thus far has been one hundred percent amazing. My life is so much better that I cannot express it in words. My oil is controlled and my pores have close up. Some pores were so damaged from years of popping and picking that they didn't close all the way. So I still have a few big pores in a several areas. I could probably finish the job with some laser type therapies that my Derm and I have discussed once I get off the drug.

So in short low dose Accutane has worked wonders for me. I have Zero side effects that I can detect. It has been like taking a vitamin pill. It is a shame we are in danger of losing this drug. In light of recent events and lawsuits drug makers are re-thinking their bottom lines. Roche has quit selling it, and a few drug makers say they will continue. So for now it appears we can still get Accutane. It is a shame that low dose therapies were never really explored in the good ole USA.

In closing: This drug, like all drugs has side effects. Different people respond differently. If you have excess oil, mild Acne or Rosacea or both, think about low dose. It might be your ticket. However, there is always a risk with any drug.

Best Wishes
LowTane ;)
Tourista, did you create a portfolio of studies as I suggested? Take in actual documentation and ask what their opinon of the study is......Pubmed and Medscape have plenty of studies on Low Dose therapies... If you didn't try this approach, give it a try and see if that helps. Also, what are your symptoms? Do you have cystic acne? Mild oil? What exactly. It could have affected their decision. You have to sell the low dose idea to American Derms.


Best Wishes

LT
[QUOTE=LowTane;4045543]Tourista, did you create a portfolio of studies as I suggested? Take in actual documentation and ask what their opinon of the study is......Pubmed and Medscape have plenty of studies on Low Dose therapies... If you didn't try this approach, give it a try and see if that helps. Also, what are your symptoms? Do you have cystic acne? Mild oil? What exactly. It could have affected their decision. You have to sell the low dose idea to American Derms.


Best Wishes

LT[/QUOTE]

Yes, I did take your advice and printed out the studies - although there are these studies, the Derm told me that the dosage amount is not approved by the FDA and that if he was to prescribe me the accutane it would start at 40mg, to 60mg, than to 80mg.
My acne is a combination of cystic, blackheads, whiteheads, etc. I have oily skin. Tan skin.
I've had acne for over 20 years and am at the age where it scars and creates pits permanently. Even my mildest acne :(
I also have uneven blotchy skintone and enlarged pores. I noticed that after the acne has gone the red marks are still existent and do not fade.
All this going on with my face has affected me emotionally and socially.
Still here.....

I am currently taking 10mg once every 2 weeks, so far so good. I am looking for the bottom here. Still no acne.... however Rosacea flushing is a little worse. Looks like mild sun, no papules or bumps. I don't think I can get much lower. Loving the low dose oil control.....

Best

LT
SawBuck, could you please post your son's details. Dosage, weight, age, severity of Acne, total amount of Accutane taken to date..... thanks. I hope he gets better.


LT

PS. Disregard, I found the details posted earlier. "

Hi LowTane, my son is 17, weighs 190 lbs., 6' 6" and started 90mg of accutane a day - two days ago. I am documenting his progress with journals and pics. He takes 50mg morning, and 40 mg at night. I will start my own thread soon. thanks for sharing your story!"

This is definitely not low dose, I wish you the best.

LT
Howdy all......

I have a Derm appointment coming up in two days. I have really gone low, Its been 3 full weeks since I have had my usual 10mg Accutane dosage. I have had no increase in oil, rosacea or acne symptoms. This is the longest hiatus I have had since starting this drug in February of this year. I am not sure where I am going with this at this point. I am now curious to see how long I can go without it before the oil starts to flow. This drug has been an absolute miracle for me. For now I will reduce to one 10mg pill every 3 weeks. I will wait for the zits and the oil at this dosage for a couple of months. I am stock piled now so I can increase my dosage on short notice. This has become very interesting. My Derm and I discussed skip dosing 1 month on and 1 month off.... I will let you know more on that after my appointment.

LT
Hello Lowtane! First off all congratulations for creating this very interesting topic. I'm not going to bother you with details of my acne/oiliness story, just saying that after realizing that accutane is the only thing that works for me, and every time I am off my acne returns (I did 2 full 6 months courses in the past) im considering a similiar regime from now on. Im planning on taking 10mg daily until I get clear and then im not sure how Im going to be taking accutane. Let me explain:

Do you now whats the difference of taking for example. two 20mg pills each week or taking 4 10mg pills also for each week (the cumullative dosage is the same), or even taking 10mg daily for 10 days and then 20 days off and then again 10mg for 10 days and so on(this would be almost the same as taking 10 mg 3 times a week. Well i think you get my point. Im confused on what is a better aproach. Ive seen various studies when they talk about this but i cant figure out whats the difference. =/ sorry for any english mistakes and good luck with the resto of your regime!
It is amazing that the low dose approach for lesser maladies has not taken precedence. I have read that celebrities have been using this low dose oil control approach for years. Can't confirm this however.... I can speculate that the strict controls on this drug stem from the birth defects that this drug can and has caused. Horrible, babies with no ears, noses etc.... getting pregnant on this drug at any level of dosing is dangerous. When you think about the birth defects and the fact that the exact mechanism that causes Accutane to work is not fully known you can see why the FDA has such a tight grip on this drug. I do believe it will always be available somehow. It is manufactured in other countries. Low dosing is very much accepted in other countries. See referenced links in this thread for Pubmed and Medscape to confirm. Changing subjects here, I have no excessive oil or Acne at this point. I went in for my first Laser treatment (YAG Laser) and my veins in my nose have already started to disappear and my pores are smaller yet. 250$ a treatment. I have 3 more treatments to go. By my last treatment I will have been off of Accutane for around 5 months. Just to remind you readers out there of my past dosing. I started at 20mg daily for a 200lb male of 48 years of age. I tapered that dose in an almost linear fashion over 6 months down to 10mg every two weeks. So, I went very low dose. I have had Acne, Rosacea and Sebaceous Hyperplasia (oil) for quite some time before trying Accutane. All have come under control on extreme low dosing. My Acne was not deep cyst type acne. Affected areas were nose and chin. Accutane change my life. I recommend printing low dose studies referenced in this thread at Pubmed and Medscape and take them to your Dermatologist. They may or may not play ball. Don't blame them, licenses are at stake for off label treatments. They are more likely to prescribe high dose therapies. I still believe that less of a drug is not a bad thing if the results are the same. But that is each persons personal choice. Its not a good idea to keep your doctor in the dark. I told my doctor every appointment that I was taking less Accutane. He went with it..... When you approach your doctor with internet information they will freeze up. Make sure they know that what your reporting to them is gleaned from official reasearch databases. Pubmed and Medscape. They may be familiar with these sites. Even armed with this information you should know your doctor is restricted by FDA. I guarantee you that if you were trying sell your doctor on higher dosing you would have no chance of success. So far low dose has worked miracles for me. All drugs affect different people differently. Low dose that works for one may not work for another. Don't take this drug under the table, you need blood work. You could die. Cholesterol, Triglycerides and Liver enzymes need to be monitored. Also know that some individuals have trouble long after discontinuing Accutane usage that may or may not have been caused by this drug. I think this drug can be extemely dangerous for some. However 14 million have been served in the USA. So, the number of lawsuits is small compared to this huge number. Worldwide even more have taken this drug. I wish you the best, if low dosing is something you wish to try, go plead your case and see if you can get your Dermatologist to bite. Best Wishes

LT
Well OL, this was the point I was waiting for...... You have had a more conventional dosing regimen. I have had a pretty short term low dose regimen. We both are clear of Acne. I am having no Rosacea problems as well. After your last dose I hope you will start to report as will I the results on a regular basis. I am glad all is going well for you.

Best
LT
49 year old male.
Rough estimates of dosages follow:
Started 20mg daily Accutane (Isotretinoin) Feb of 2009
Reduced to 20mg every other day after 2 months
Reduced to 10mg daily for one month
Reduced to 10mg every 3 days for one month
Reduced to 10mg once a week for 2 months
Quit Accutane

I have (had) Rosacea that flared with pustules along with Acne Vulgaris on the nose and chin. Sebaceous Hyperplasia (max oil) afflicted me as well. I researched low dose Accutane and found multiple studies in other countries where outcomes were extemely positive. I found these studies on legitimate sites that report research outcomes. Pubmed and Medscape mainly. I took the studies to my Dermatologist and showed him the results. He tried it with me and I have had great results. Its true that the low dose approach may not work for everyone. Its also true that the high dose approach may not work for everyone. Ingesting a drug until your nose bleeds and your eyes dry out doesn't appeal to me, it never did. I wouldn't commit to high dose therapies. It was never an option.... It should be noted that millions have tried the high dose therapy and have had success. In light of the bad press Accutane has had, a low dose movement would be welcome. When you approach your Derm don't mention blogs. Ask him or her about research papers that you found on Pubmed and Medscape published from Dermatologists in other countries. See if you can get them interested or at least talking about it. You can always go high dose later if low dose doesn't cut it. Accutane changed my life for the better, no doubt. I have had success so far and zero side effects. I didn't even have dry lips. My pores have closed up, my oil had dropped to normal levels. My Rosacea has abated. My dosage was extemely minimal. I pray they don't pull this drug from the market. It has saved my life, my career and restored my self image. I may need it again, its to early to tell. I have been off of it for a couple of months now. I am getting laser treatments for pores and veins in my nose. I will continue to report the post Accutane results until it doesn't matter anymore. Please read this entire blog for more hints and tips to my approach. The fact is, very low dose therapy worked great for me so far, and no side effects. Less risk. Dermatologist will tell you that the exact mechanism that causes Accutane to work is unknown. Understand that Doctors are going off label and risking licenses even though they are giving less of a drug. Seems strange, but its true. The FDA has stringent guidelines for this paticular drug. Know for a fact that this drug can cause severe birth defects at any dose. Know also that some people suffer horribly from the use of this drug even years after ceasing usage. Although this hasn't been conclusively proven some court cases have been won. These patients swear this drug caused their problems. I believe it to be possible. I also have an opinion that high dose is what caused these individuals to have long term problems. However, millions have taken this drug high dose with no problems reported. Drugs affect different people differently. My results may not be your results. Never self medicate with illegal drugs from the internet. You must have blood work when using this drug, you could die. See your doctor and ask for a low dose approach. See what happens.


I wish you the best.
Hello all... I have been off low dose Accutane for about 2 1/2 months now. I have had a couple of zits on my chin and nose. They were small and cleared pretty quickly. I was alarmed. But I am still staying clear at this point. I have had noticeable oil at the end of a long day. After washing it didn't come back or pool up like it used to before Accutane therapy. My Rosacea has been in check. I talked to my dermatologist about this and he said there is no precedent for Accutane and Rosacea. Well, there really is, multiple studies exist that were completed by vaild researchers. Consult Pubmed and Medscape for recorded studies. I wish Doctors in the US would consider low dose alternatives more frequently. It has been a short time for me since I have ceased Accutane. So the other shoe may drop shortly. The best I can do is to continue to describe what occurs in the coming months. I will do this..... I believe that low dose may be the answer for some people. Everyone is different. I have heard many reports from individuals who have been on Accutane serveral times, while others only once. I have read reports where acne has come back and others where it never returned. Still, Accutane is the only thing that has ever helped me. Its fair to say, that down the road I may have health issues from my experience with this drug. However, many people have reported that they have not had long term problems, even from high dosing. To all of you who land on this page, please remember to tell anyone of concern about low dose possibilities. Direct them to vaild reseach studies found on Pubmed and Medscape. These items may help them with their dermatologist. Maybe some day low dose therapies will be commonplace with this controversial drug. Rememeber don't self medicate with illegal drugs obtained on the internet. Accutane really does require bloodwork monitoring to be safe.

LT:wave:
Hi there,
I'd like to thank you for your updates, Lowtane and Old Lawyer. They have been most informative. I wanted to show you what you have inspired in me and my story. I have included dates from when I started recording this.
Weight:75Kg
Sex:Male
Age:35
Case: Moderate acne since 14 controlled by daily vigorous exercise and over-the-counter treatments and extremely low fat and suger intake.
By controlled I mean only a bad pimple every couple of weeks instead of every day. This has been continous and my skin, although clear on some days, still had the healing marks of the pimples from a few weeks ago, so I never was clear in that sense. Luckily for me, my skin heals quick quickly and with little scarring. This year I made up my mind that, even if it kills me, I will rid myself of acne. The OTC stuff never really helped keep my pimples at bay.
My First success!
Aug 7 2009: My first success was with the treatment using large B5 dosages, 6 grams a day. The long term affects of this are unknown, but I can tell you that the short term affects are miraculous.
Aug 21 2009: My skin was clear of new pimples and the old ones have alomst healed up. This cleared me up quite quickly and finally gave my skin time to heal (to the point that one girl who had just met me, on finding out I had a brain, said "I thought you were just a pretty boy". I have never been a pretty boy before!)
After a lot more reading about it I found that this is not a permanant cure and it's long term affects are largely unknown. There are some case studies of individual paitients suffering terrible side effects after a few years of this, however they were individual cases and not a study on a group. They could be isolated cases (1 in a million chance of happening) or it could be unrelated, however the odds are unknown and I decided to seek a cure more proven.
15 Sep 2009 : Introduced 20 mg a day of accutane, 6 grams of B5. This decision was mostly inspired by this thread the Lowtane and Old Lawyer have been posting too.
17 Sep 2009: Wasn't ready for the dry lips and face of accutane. I dropped to 10 mg a day, 6 grams of B5.
20 Sep 2009: Feeling better and more prepared (with lip balm) and back to 20 mg a day, 6 grams of B5.
26 Sep 2009: Dropped to 4 grams of B5 a day, keeping at 20 mg accutane. Face is getting a bit red.
28 Sep 2009: Accutane is holding well with the drop in B5. Very dry skin but not too much flaking.
30 Sep 2009: One small whitehead, the first since 2 weeks after I started B5.
6 Oct 2009: Down to 2 grams of B5, 20 mg of accutane.
9 Oct 2009: Down to 1 gram of B5 a day, increased to 40 mg of accutane for the weekends. I believe that I can take extra accutane over the weekends as I am not going out much. I have basically shut my life down and I am living like a bit of a hermit (well, no big parties) until I have my face under control again.

To get to my conclusion, so far a low dose accutane regime seems to have almost taken over the role of B5 in 3 and a half weeks. Both methods target dropping the production of skin oils although in different ways. B5 takes away the fuel (makes fat just under the skin break down), whereas accutane makes the engine smaller (makes the skin oil glands smaller). Accutane, being the only permanent cure seems like the obvious choice.
Can I gather that you found that you acne was controlled by low dose accutane in about a month? Although you are 15 years older I believe that our problems are closer related than I would have to a 15 year old.
I hope to one day be able to update a thread with "Off accutane, face clear".
Hello everyone! I can tell you that my oil is not the same as pre-accutane oil. I used to blot 20 times a day. I sometimes now find oil on my face in the very early morning or late in the evening after a long work day. I am still Acne free except for an occasional pimple. It has only been about 3 months off of Accutane now. I was a pretty low doser. I don't know what to expect from here on out. My Derm says come on back at the first sign of trouble. Accutane has been a godsend for me. I have had two laser treatments since my Accutane cessation. They are doing a great job on my pores. My Rosacea has been in remission since the start of Accutane. I had a few flares in the first month of Accutane usage and then it subsided. I am not sure how long I will stay clear at this point. I will continue to post periodically to let readers know how I am doing for the sake of curiosity. I will go back on low dose Accutane if need be..... Remember, I support low dosing of this drug and have a great fear of high dosages. I do believe that high dosages have harmed some people. However, some individuals seem to do fine on the high dosages. I just don't want to be made to bleed from ingesting a drug. Doesn't seem like a good idea. Be sure to use Pubmed and Medscape while building your case if you feel like going low dose. Remember that Doctors are skeptical of anything that has to do with the internet or anecdotal blogging. You got to sell them on the legitimacy of the studies that you will find on these sites. Accutane may of may not work for everyone. It was a miracle for me. I still wonder if down the road I will pay some sort of price for using it. You need blood work with this drug for sure. Don't self medicate. Try to convince your Derm that low dose is for you. Remember that even giving less of this drug is still off label. Doctors resist off label treatments to protect their licenses and I don't blame them.....

PS. I had oil during Accutane treatment, just not a lot. I am about the same now post Accutane.

Best of Luck
LT
Hi,

I have just started accutane (was on a standard dose aged 16 - 60mg daily I think). Worked to clear my cystic acne but still suffer mild/moderate acne. Just started another low dose course but after just 2 days at 20mg I have experienced significant facial flushing. It's really depressing me as I thought I would avoid this dreaded side effect at such a low dose. I've skipped a day and intend on perhaps taking another 20mg pill tonight but fear that the reaction will continue. Did you experience a worsening in your rosacea (not sure if this is rosacea but I expereienced the same thing on many topical treatments) at the beginning of your course? I know 10mg daily is often used to TREAT rosacea so really didnt expect this so early on. Any advice/words of encouragement would be much appreciated. Also I switched from Differin to Accutane almost immediately so dont know whether this would be a factor, and have been drinking a fair bit.

Regrds,

Tom
Tommy, I don't know if this helps or not. I experienced quite a few facial flushing episodes when I first started Accutane. They went away. My face still has a slight weathered glow of very light red on the cheeks. It appears like mild sun exposure. The biggest thing for me was that the pustules and infections caused by Rosacea were gone completely. Many Rosacea sufferers report that there is a magic dosage that works for Rosacea. Usually lower than the amount required for severe acne. I was looking for the dosage that bordered acne and Rosacea symptoms. 10mg every other day is where I ended up for the bulk of my treatment. I am 200 pounds and somewhat sensitive to drugs. Again, time is the factor here. The longer I stayed on the low dosage the more stable my symptoms became. Everyone seems to have different reactions to different dosages of this drug. You could ride it out a little, pick your dose and stick with it and see what happens. I started higher than I wanted and continued to taper it down over time. My goal was to find the lowest dosage that would keep my Acne and Rosacea in check. Since you have taken this drug before you proabably remember it takes time for you to stabilize. I wish you the best of luck.

LT
I just re-read your post Tommy. Drop the alcohol completely. Drink lots of water and eat fruit and salads. Go low fat on the meats and dairy products. Get a good multiple vitamin. Cut sugar out completely. Try working on a positive mental outlook. Not a single animal in the wilderness has Acne or Rosacea. We humans have managed to muck up a lot of things in society. You will have much better results with Accutane when applied to a healthy body.

I wish you the best...

LT
Now for my post, 4 small surface pimples but no real oil. They have appeared and healed quickly. I am trying not to worry about it. I am going to stay off Accutane regardless. I want to see how long this lasts without the support of low dose treatment. Its the only way this journal will be significant. If I can have long term remission on low dose Accutane then maybe there is hope for other people on this drug. I am still against high dosage, it is my personal preference. I fear this drug greatly. Low dose has been easy, no side effects so far whatsoever. Complete clearing of Rosacea and Acne symptoms resulted. This was achieved on a average dose of 10mg once a week in the last couple of months of treatement.

I wish you all the best..

LT
Thanks for the advice. I will as you say "ride it out" and try and establish a happy medium between what controls my acne and keeps my flushing symptoms at bay. Hopefully this intial worsening is going to pass and is a result of my body adjusting to the treatment (layman's biology!). I have just moved to a new city here in France where I took up a bar job before starting roaccutane so its pretty difficult to avoid alcohol...sometimes its easier to knock back the drinks offered to me than explain that I'm on medication for my acne that works better in an alcohol free body, I'm british as well and work with brits and yanks so drinking is pretty integral to many social occasions...I'm trying to cut down but not always easy without drawing attention to my plight with acne/potential rosacea!! So far not toooo bad though since spreading out/reducing the dosing. Hopefully things'll plateau eventually!
[QUOTE=TommyBlates;4104383]...I have just moved to a new city here in France where I took up a bar job before starting roaccutane so its pretty difficult to avoid alcohol...sometimes its easier to knock back the drinks offered to me than explain that I'm on medication for my acne that works better in an alcohol free body, ...[/QUOTE]

Thought I'd pass along a trick I learned from the movie Coyote Ugly. The girls always get drinks bought for them. One girl takes an empty beer bottle and after she drinks (shots usually) she "chases" it with a swig of beer. No one knows that she spits the alcohol into the empty beer bottle!

My son is 17, 195lbs, 6'6", been on accutane for 3 months. He is doing well. Went through dry lips, initial breakout, tiredness, mouth so sore he couldn't talk. Most of that only lasted a week. He works out every day. Serious weight lifting and cardio. He has bulked up. He is on 90mg daily. 50 in am and 40 at night.
[QUOTE=alexusf13;4104634]Hey i cant get this. What is this thread all about.[/QUOTE]

This thread is about two guys who started Accutane about the same time. They are about the same height and weight. One guy started with Moderate to normal dosing and one guy started with what is considered low dosing. Both have Rosacea and Acne. Both were moderate drinkers. Both have reported there results throughout this thread. You will have to start from the beginning if you want to know more......


Best
LT
I am around 3 months off Accutane. I have had two laser treatments for pores and veins on my nose. My face looks better than it has since I can remember. The last couple of months I was on Accutane I was only taking 10mg once a week. Ridiculously low amount. I don't have much oil on my face. I have some....I get small pimples once in awhile on my nose only and they clear fast. I am still waiting for the other shoe to drop. I have had aching joints from time to time. I don't know if it has anything to do with Accutane, although some people have reported this malady. Because of my low dosing with normal prescription levels I have quite a stockpile of Accutane in my medicine cabinet. My Doc says to come back at the first sign of trouble. He seems comfortable with the low dosing oil maintenance idea. My Rosacea is absent other than a mildly sun flushed appearance that looks like I had light sun from time to time. Acne vulgaris on my chin has not flared once. So far so good. It is very early yet, some people report that the acne stays in remission for up to a couple of years or more. I am prepared to low dose continuously if I have to some day. Oldlawyer, please keep up the posts, I am very interested to see how it goes for you.

Best Wishes all...

LT
hi there,

i used to frequent this form a lot over the years having suffered from moderate acne for 20 years. i tried everything -- and i am not exaggerating -- until i found a derm that talked me into acutane. luckily for me, i was at my wits end and the treatment was covered by my health insurance so i figured it was worth a shot. i was nervous for sure, but willing to try one last time before resigning to the fact that i would have pimples on my face until the day i died.

long story short, i took a low dose of 20 mg/day for 7 months (a lesser dose than the dr suggested) and i have been acne free for one full year. and i mean FREE. not. one. pimple. it's a miracle for sure.

with the low dose, i had few side effects but made sure that i supplemented my diet with vitamin e and LOTS of water. i had a constant aquafor on my lips and up my nose the whole time, but for me the biggest hassle was the monthly blood work and follow up visits. it's a full time treatment that requires a lot of persistence.

recently i went to get a facial and the aesthetician said my skin was perfect. !!!! but here's the best part -- i just got back from my first tropical vacation where i didn't even consider bringing concealer to cover up my spots. (ladies, you know what i'm talking about!) just a bunch of sunblock.

anyway, just wanted to thank you all for sharing your stories... even though i was a lurker for years, the forum helped me so much as i'm sure it does to many people.

thanks!
Well you sure don't post as much when your acne is at bay..... I am off Accutane for around 4 months. My oil has increased slightly with only an occasional pimple. Pores are about the same. All is still well. I am still waiting for the other shoe to drop. To new readers of this blog.... I am a 50 year old male about 200 pounds. I tapered from 20mg daily to around a 10mg once a week accutane dosage over a period of 6 months. It has put my acne vulgaris and my rosacea in remission. I don't get the red flashes and pustules or zits any more. I had tried everything over the last 35 years. I believe in the low dose regimen. I had virtually no side effects at these dosage levels. I have recommended repeatedly on this blog that individuals go to pubmed and medscape and create a portfolio of low dose studies to present to their dermatologist. They may or may not listen. I am no expert of any type, but I have the opinion that dosing at levels that make your nose bleed and your lips crack off your face may affect other body parts in an adverse manner. I just couldn't get myself to agree to those levels of this controversial drug. The argument is will lower dosages give long term results? Well, I am testing that theory on at least one person. Accutane improved my life one million percent. Dried up my oil, closed up my pores, cleared my Acne and killed my Rosacea. The extreme social unease that I have been living with is gone. Remember to strategize when approaching the doctors with the low dose idea. It is not prevalent in the USA, be sure to tell them that PubMed is a service of the US National Library of Medicine that includes over 18 million citations from MEDLINE and other life science journals and that medscape is a physicians resource site. Do not tell them stories from blogs with personal accounts like this one. They consider the information anecdotal and unsubtantiated. I agree with them on this point.

Good Luck

LowTane
Hello all....

I have now been off Accutane for around 5 1/2 months or more. I am losing track of time. As a reminder to anyone who comes to this board, it all started with me wanting to try low dose Accutane and see if I could get the same results as Higher dose therapy. I am 50 years old and weigh 200lbs. I am a male with Rosacea and Acne Vulgaris. I started on 20mg daily and tapered down in a fairly linear fashion to 10mg once or twice a week. Accutane cleared my Rosacea and my Acne. I am still clear at this point. The method I used was to submit Low Dose studies from Medscape and Pubmed to my Dermatologist. I told him I didn't wish for High dose, he acutally started me at a higher dose than I wanted. I tapered it down quickly to lower dosages. He always seemed very suprised when I would tell him how little I was taking of this controversial drug. I suffered virtually no side effects whatsoever. Accutane changed my life, period. It may work for you too. If you fear this drug like I did, consider trying the low dose route. If it doesn't work you can always try a higher dose regime. Many other countries are prescribing this drug at lower dosages with great effect. Consult Pubmed and Medscape and you will see.

Best Wishes
LowTane
Heading for 8 months off of Low Dose Accutane!

Treatment Duration: 6 Months

Dosage: Started at 20mg daily, tapered over 6 months to 10mg once a week.

Age: 50

Weight: 200

Sex: Male

Side effects: Extremely minimal, light drying of the lips.

Results: Cured my Acne Vulgaris, shrunk my pores by 90%, put my Rosacea in permanent remission, adjusted my attitude from deeply depressive solitary behavior to upbeat outgoing positive socialite.

Strategy: Use legitimate studies on low dosage Accutane published on pubmed and medscape to convince my Dermatologist to give it a try.

Comments: My philosophy is that drugs are bad in the first place. I will never submit to the high dosages of this drug administered in the USA. Other countries are embracing low dose treatments and getting great results. With the low dosage approach my fear was minimized. I feel I could do it again if need be......Anyone going through what I did with Rosacea, Acne Vulgaris and Sebaceous Hyperplasia (massive oil) gets my total sympathy. I don't know if my approach will work for you. It just makes sense to try this drug in a very low dose to see if you can tolerate it. You can always try a higher dosage later on. Do you homework and copy legitimate studies and take them to your Derm. Don't take in stories and blogs, they will not listen to anecdotal data. Ask them if they know of Pubmed and Medscape reporting agencies. Be organized, be firm. There are multiple countries who have published studies on the efficacy of low dose Isotretinoin (Accutane). I wish you the best.

LT
Thank you so much for your blog. It was of tremendous help to me. Today I began 40mg/day of Claravis. My doc would not agree to a lower dose, even tho' I requested it many times. 6 mos is my planned duration. I did visit another derm yesterday who is out of my network, who agreed that if my acne comes back after 6 mos, he'd put me on 10mg/day (possibly for a long term). I am 51, 5'6", 120lbs. Thanks to your blog, I'm armed with info, and am asking questions. I pray it works for me with minimal side effects (after 37 yrs of cystic chin acne), as it did for you. Thanks again-





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