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Low Dose Accutane
Feb 6, 2009
6 Feb 2009
Hi, I have just taken my first low dose of Accutane
Brand:Sotret
Weight:90Kg=200lbs
Sex:Male
Age:48
Dosage:20mg once daily
Supplements:None

Day 1
Chronic oily skin, blotting on the hour. I have mild Rosacea and more severe Acne Vulgaris of the nose and chin. My dermatologist in the USA had no real off label experience with low and microdose accutane. I brought him multiple studies from Israel, Turkey, UK and more.... he was interested. I have a back-up of Eythromyacin, I am hoping not to use it. I have been on Doxycylcline for the last year (this is not allowed with Accutane) since being diagnosed with Rosacea. My derm will only allow for a one month antibiotic security blanket. Eythromyacin does not have contraindications with Accutane, when its gone I have to ride it out. I am Professor at a local college, needless to say it is difficult to have skin problems and have to lecture in front of crowds. I hope I am lucky and can avoid the dreaded intial outbreak so many Accutane users report.

Best Wishes
LowTane

Declarative statement: I am not recommending this drug. I am only reporting results in the most objective manner I can muster. I do believe this drug can be dangerous. I am taking this risk of my own accord. Please read other blogs that discuss the seriousness of possible long term side effects.
10 Feb 2009
Brand:Sotret
Weight:90Kg = 200lbs
Sex:Male
Age:48
Dosage:20mg once daily
New behavior: No soda pop of any kind

Day 5:
Well I took my 4th pill last night. I know it sounds crazy but I can see changes already. I have even more fear of this drug than I had in the first place. It has to be powerful to have these effects in the short term. I definitely am waking up with less oil on my face. My first day of work was met with 50 percent less blotting with tissues. I had several events where I felt I had flushed (rosaceans pay heed) under some job stress but checking in the bathroom showed just regular looking skin. My Acne has not burst forth in the abscence antibiotics yet. Pores seem slightly smaller already. The mild lip drying is still present. I have no reported side effects with the possible exception of the lip drying and maybe one other. My libido seems to have taken several steps backwards. It should be noted that all of the results I am reporting could be due to just coincendental factors. Inside though, I really think it is this drug. I have read other Accutane logs with similar results. I am trying to be very objective, I pay attention to small details. One other thing that is definitely happening is the anti-imflammatory effect. My skin color is more even and red veined areas are looking less apparent than they have in years. I realize this is only 80 milligrams of Accutane and the diet changes could be part of this...... I don't know. It seems impossible to already be feeling the effects of this drug, but my oil ouput and skin color has shown changes. I know, I have to look in the mirror every day. I will continue to log results, I expect the suspected effects to become more apparent as time goes on. Then I can report with more confidence what I am already suspecting. I remain mildly optimistic wondering about what I am experiencing. I am thinking of asking my Derm to reduce the dosage to 10mg.

Best Wishes
LowTane

Declarative statement: I am not recommending this drug. I am only reporting results in the most objective manner I can muster. I do believe this drug can be dangerous. I am taking this risk of my own accord. Please read other blogs that discuss the seriousness of possible long term side effects.
11 Feb 2009
Brand:Sotret
Weight:90Kg = 200lbs
Sex:Male
Age:48
Dosage:20mg once daily
New behavior:None today

Day 6:
Well, I will be taking my 6th pill in a few minutes. I gotta tell ya, you probably won't believe me though. My pores which I double checked with my Wife are reduced by over 50 percent. I was blotting 10 times a day with tissues to soak up oil. I now blot 4 to 5 times a day during work. My acne was under control from a year on Doxycycline, so I didn't have much when I started Accutane. However, by now I should be breaking out gang busters with Acne Vulgaris all over my nose. Ususally my nose is throbbing from the swollen sebaceous glands. It is feeling of normal size again. It actually looks smaller. It is like a switch has been thrown and my oil glands are being told to stop. My pores are shrinking at a rapid rate. A 100mg dose (20mg once a day) of this drug has caused these reactions in only 5 days. I say it again, I am very scared of a drug that has this powerful effect in that period of time. To the rosaceans who may be vieiwing this log, I feel extreme hot flushes in the cheek but not my nose, however when I check to see how bad it is, it is insignificant. I look mildly flushed compared to how I used to look. My side effects are extremely mild to none. Slightly dry upper lip is all I have..... I have read many horror stories about this drug, I won't go into the details. So, my fear levels are high. I am happy and at the same time scared to death. I really want to take even lower doses. I have considered getting gelatin caps and a syringe and drawing out 5mg doses to put in the caps. I wished this came in pill form so I could break them into pieces. I am not sure what I am going to do yet. It almost feels as if my body needed this, it makes me wonder how it works. Its like something out of whack has been corrected. Some individuals lives are ruined by this drug. I find that it is the high dosers who report the worst problems. Low dose this drug might just be heaven sent. My job is already one hundred percent better. My wife is throwing a party this weekend and I am actually looking forward to it. Miracle or curse......we shall see.:confused:

Declarative statement: I am not recommending this drug. I am only reporting results in the most objective manner I can muster. I do believe this drug can be dangerous. I am taking this risk of my own accord. Please read other blogs that discuss the seriousness of possible long term side effects.

Best Wishes
LowTane
12 Feb 2009
Brand:Sotret
Weight:90Kg = 200lbs
Sex:Male
Age:48
Dosage:20mg once daily
New behavior:None today


Day 7:
I have had mild rosy cheeks and nose today every so often. Once for an hour or so. I do believe that the magic dose for my rosacea symptoms is probably lower. Most Rosacea forums report success with low doses. The trick is if you have both Acne Vulgaris and Rosacea to find a dose that is just right for both afflictions. Low dose studies show that 2.5 to 10 milligrams for varying sizes of people seems to work very well for Rosacea. Low dose studies for Acne seem to hover around 10 to 20 milligrams for varying sizes of people. I am going to ask for a reduction to 10 milligrams this month when I see my Derm. My skin is already looking better just because of the greasiness being minimized. Pores aren't so hideous. If this drug has this affect this soon, I wonder how fast things could go bad if I stopped taking it right now? The throbbing swollen feeling my nose has had for years is minimal now. Skin is dry and feeling smoother already. My wife has noticed the difference too. I kid you not, this is like a biological switch has been thrown. I have been waiting for the acne to explode, so far nothing. If I don't explode in another week with acne I will begin to believe that Accutane is suppressing the bacteria that causes acne somehow. Well for now I will stay on this dosage. It is so early in this trial that some readers must think I am nuts and imagining the results. I have considered that maybe I am just hitting one of those acne free windows and this is a coincedence. One thing I have noticed is the parts of my face that are not normally oily are very dry and smooth. My whole face feels tight. I am using Cetaphil on my cheeks. If my Derm won't go for a reduction in dosage I may move to skip dosing and take 20mg every other day. Well thats all for now, gotta go take pill number 7.
:wave:

Ps. I mentioned a Libido scare a few posts ago, well it checks out fine. (Well, for a 48 year old anyways!) ;)

Best Wishes
LowTane
18 Feb 2009
Brand:Sotret
Weight:90Kg = 200lbs
Sex:Male
Age:48
Dosage:20mg once daily

Day 13:
I gotta say, that Accutane changes the normal process for a zit. I was already for a long drawn out process for my new acne. It started very painful as usual, but.... my zits are drying up quick. Its as if they are drying from the inside out. Pain came and went. The normal expected redness and swelling is very mild in comparison to past acne events. Wow, I am loving this drug. Pores that I expected would need surgery are much, much reduced in size and appearance. Oil is still very well controlled. I have no side effects whatsoever. My attitude is improved 100%. After reading all the horror stories online I was braced for the worst. I might as well be taking a vitamin pill. I am thinking that the Europeans have it right. We are giving much to high of dosages in the United States of this powerful drug. Pill #13 goes down tonight.

Day 13: cont-
I just took pill #13 a few moments ago. I have two zits on the chin and 3 on the nose. They are not that red though. It really is a lot easier to deal with the zits on this drug. I hope this does not last for weeks. It would be nice to get past the intial breakout. To the Rosaceans. No flushing at all, no hot skin...nothing. It seems this drug does control Rosacea. The downside is I have heard it doesn't cure it like it can Acne. When all is said and done the next hurdle may be getting a Derm to commit to long term Microdose Tane. Well, good nite.


Best Wishes
LowTane:D
I started on Monday 2/16. I am 48, male,190 lbs and am on 40mg/day. My systoms are similar to your except I was on tetracycline for 11 years (absurd, I know) and everything else that did not work. My breakouts were usually not bad, mostly on the nose and trunk. My face started to get really read last October and it took me 4 months to get a derm appt. Since nothing else worked, including prescription creams, they said this was the best option.

I decided to quit drinking while I am on it...will make friday nights rather dull, but I like my liver.

The first day I had some mild headaches. The second day I broke out a little, but I`m not sure if it is from the accutane or the fact that I stopped using everything else. Today I was a little more broken out but they went as quickly as they came, which was strange. My eyes get very dry about an hour after I take it (with dinner) and that lasts for an hour or 2. My skin is less oily, for now. I sleep like a rock.

I was told to drink a lot of water and exercise and eat well.

My 19 year old daughter just finished up. She was never that bad but nothing got rid of her mild acne so she tried it and has flawless skin.

Good luck. Keep in touch.



[QUOTE=LowTane;3877069]6 Feb 2009
Hi, I have just taken my first low dose of Accutane
Brand:Sotret
Weight:90Kg=200lbs
Sex:Male
Age:48
Dosage:20mg once daily
Supplements:None

Day 1
Chronic oily skin, blotting on the hour. I have mild Rosacea and more severe Acne Vulgaris of the nose and chin. My dermatologist in the USA had no real off label experience with low and microdose accutane. I brought him multiple studies from Israel, Turkey, UK and more.... he was interested. I have a back-up of Eythromyacin, I am hoping not to use it. I have been on Doxycylcline for the last year (this is not allowed with Accutane) since being diagnosed with Rosacea. My derm will only allow for a one month antibiotic security blanket. Eythromyacin does not have contraindications with Accutane, when its gone I have to ride it out. I am Professor at a local college, needless to say it is difficult to have skin problems and have to lecture in front of crowds. I hope I am lucky and can avoid the dreaded intial outbreak so many Accutane users report.

Best Wishes
LowTane

Declarative statement: I am not recommending this drug. I am only reporting results in the most objective manner I can muster. I do belive this drug can be dangerous. I am taking this risk of my own accord. Please read other blogs that discuss the seriousness of possible long term side effects.[/QUOTE]
Hi Low tane
Been reading your posts with interest as i've just started on low dose accutane myself.
Quick bit of info about myself;
I'm a 26 year old male who has suffered from mild/moderate acne with excessively oily skin for around 15 years. Weigh 75Kg
Took my 6th 20mg accutane pill today - brand i'm using is Roche.
From the first day i noticed a reduction in oil and everything seemed to be going great until yesterday. Noticed that i seem to be getting some rosacea symptoms that i didn't have before. My cheeks seem really hot and i look slightly read (not as much as i feel!). If this carries on i may reduce my dose to 1 tablet every 2 days so my dose would be 10mg per day. That's the only side effect i've experienced, still have acne on my forehead, but spots seem to be drying up nicely. Will keep posting on here. Be interesting to compare my progress with yours as i'm not too far behind you!
OldLawyer LOL... Talk about hitting the nail on the head. Man I am keeping a close eye on this libido thing. I have never really had to come to terms with the possibility of losing it permanently. I still have a roving eye and my wife is wondering if I am in my second childhood. I want to test it often, which is putting me over my normal schedule. She's telling me "its fine, enough already"..... I am happy to say to all of you potential taners out there that everything still works.

5 Mar 2009
Brand:Sotret
Weight:90Kg = 200lbs
Sex:Male
Age:48
Dosage:20mg once daily

I did my bloodtest day before yesterday and I have my appointment with the Derm in a couple of hours. I am virtually blemish free and oil is no longer a problem. My back had a few blemishes, now gone. I feel relaxed and better than I have in such a long time. Life goes better without the trauma of facial acne and Rosacea. Nose is narrower and no longer throbbing with over active sebaceous glands. I will ask my Derm about the future, cumulative dose plans etc.. I have no real side effects at this point. Slightly dry nostrils, very slight and mild micro flaking of the nose. The flaking is not even noticeable unless I scrubb to hard or wash my face to long. I use cetaphil moisturizer to shave with, apply it to my nose as well and leave it on when I exit the shower. So for now, life is okay. I have taken to having a 4 oz. glass of Cab Sauv once in awhile before bed. I drink more tea than anything and I have cut soda pop almost out of my life. I did my 27th pill last night and slept like a baby. Attacked my wife this morning, just to make sure!!! All is well for now. My hair is not falling out either. More to come..... after the Doc Appt.

Best Wishes
LowTane
Definately some food for thought, LowTane. My doc tends to be a high doser, and if my body tolerates it, I will go with that. She was much more optimistic about long term results. Common sense (which is dangerous) tells me that relapses in teens with standard acne as opposed to the more vascular rosacia type would be more prone to relapses, taking hormonal activity into account. Moreover, a 10 year remission would leave us with 58 year old skin, which should be less suseptible to the markedly increased oil production. Studies on Rosacia give it a life of 8 to 15 years in most cases. Having been in this boat for 13 years, I question that prediction, but I will admit that over the last 2 years, the episodes of really bad breakouts were decreased to a cyclical one week per month (but as we know, that episode affects appearance for the rest of teh month). Here is something else that you may be interested in: Although my skin was never really blemish free, the rosacea type acne did not really start until after I caught a mild case of the chicken pox from my kids at age 35, and the really bad redness did not start until 5 months ago, which prompted my derm appt. My doctor told me that the bad thing about getting a mild case of the pox as an adult is that mild cases can affect the vascular system. Within a month after recovery from the pox, I developed severe seasonal allergies that would only respond to steroids. Also, my blood pressure rose from 110/70 pre-pox to 170/120 post pox. I am on the mildest dose of BP meds available and that gets it down to 110/70 again, but if I go off it, the BP shoots up again. Keep in mind that although my diet ok but is not the best, I have an affinity for Jack Daniels and I have a high stress job, I exercise regularly, I am not overweight and all other vitals are good. My doc maintains that the pox was the trigger for all of this, including my skin. That is why he put me on antibiotics, which only worked well for a year and did nothing for the oil or the swelling of the nose. With accutane, all of the skin issues are now gone after less than 3 weeks. After I am done with my course, I will definately raise the issue of long term low dose, and if my derm won`t do it, I will go on this again if need be. If that doesn`t work, I`ll try the light show previously discussed in this post. The best part is that there are still options.

Until next week.......all the best.
Good to hear from ya Chooch. Thats cool.. Its nice to hear from other low dosers. But I must ask, what was your outcome after your accutane experience. Success, failure? Will you take it again. Did you have a remission etc... it would be cool to hear your story.

Old Lawyer, good to hear from you. You are right, there are side effects listed for every drug. There are lawsuits for multiple drugs on the market. Also, the sampling of horror stories is small in comparison to the number of patients who have prescribed this drug. I had wanted to go with a very low dose all along to feel this drug out. I know that long term antibiotics are no option either. I am torn between long term extremely low dose maintenance accutane and going for the high dose and hoping for a really long remission. I have skipped two pills so far and my headache and dizziness hasn't resurfaced. Could have just been a fluke and had nothing to do with Accutane. My derm is going to lower my dose next month anyway. So, still contemplating my next drug move. I do appreciate your reply. Good Luck...

9 Mar 2009
Brand:Sotret
Weight:90Kg = 200lbs
Sex:Male
Age:48
Dosage:20mg every 4 days.

Day 32:

Well if you have been following along at all you know I am taking liberties with the dosages of this drug. I have backed off on the 20mg daily to 20mg every 4 days. I have no increase in oil yet from the lower dosage. I have felt better on the lower dose. My facial redness (flushed look really) is more normal skin tone now. I am still dry and have very mild flaking. I am 100 percent clear and my pores have shrunk 85%. I am loving this part of this, all things are better. I do believe some of the extremely high dosages doctors have prescribed some patients have really caused some terrible problems. My reading shows that a lot of people get remission but still come full circle back to acne and oil. Many people do this drug several times with long breaks in between. My goal is to go low and stay low and check out my results compared to hopefully someone on higher dosages. Maybe old lawyer will stay around long enough to be that guinea pig. Well all for now......


Best Wishes
LowTane
Hello, I've just started taking a low dose at 20mg a day (10mg twice a day). I'm on my fourth day and have noticed some positive changes in skin texture and oil secretion, but very mild since I haven't been on it that long.

Interestingly enough, I've had issues with my lower lip being dry for a long time without having ever taken this drug before, and I can't even remember when it started so I've experienced zero "new" side effects thus far. My hair started noticeably thinning when I was 25 so I hope it doesn't accelerate it. I shave my head very close to minimize the appearance (not bald close).

I've had acne since I was 14 and it only got worse as I aged (now 30). It started on my face then my back, chest, shoulders, upper arms, some even on my forearms, thighs and occasionally around the calf. I think I pretty much get them where sebaceous glands are most prominent.

I've been able to control it somewhat through diet (low carb, no soda or sweets of any kind) but it's been very persistent for a long time and I'm fed up with it. If I didn't restrict my diet I probably wouldn't have a job right now because my skin would look like a warzone and I'd be too embarrassed to leave the house. In fact, I'm a firm believer that the cause of most skin problems is due to the modern diet of processed foods, sugar and carbohydrates (sugar before digestion). I think my diet over time induced this condition and it may have created a chronic problem that a change in diet might take a very long time to adjust, if at all.

I've passed on some very attractive women throughout my life, to the point where I've hurt people's feelings because I'd take an interest in them but would back off because of my insecurities, so I'm prepared to deal with whatever consequences come from this experiment.
12 Mar 2009
Brand:Sotret
Weight:90Kg = 200lbs
Sex:Male
Age:48
Dosage:20mg every 4 days

Chooch, heres the part I am talking about:

A total of 617 patients completed the study. In group 95% of patients achieved considerable improvement or complete remission of their acne;

Somewhere in that 95% were low dose Accutane users who acheived complete remission.

Where low dose is concerned my thinking is that the lower doses cause less damage to vital systems. I could tolerate a minute amount of strychnine once a week for a long time. However, a full cup would kill me instantly. I know that analogy stinks but its all I could come up with on short notice. Since the actual mechanism that makes Accutane effective is unknown, I believe it warrants extreme caution. I know there are quite a few individuals out there wishing they had never seen or heard of this drug. Many other countries are reporting responsible long term usage on much lower doses. I believe it is prudent and wise to re-think western methods. Many blogs report high dosage acne relapses. If someone starts on low dose, they can always later on try a higher dosage. At least they had time to feel out the drug and see if they can gain complete remission without as high a risk. I only posted two studies, there are more from Germany, UK, Turkey, Israel, Sweden etc... They are all advocating therapies that involve lower dosages, for very good reason I believe. So, for me, I feel much better trying the lower dose regimen before committing to a higher dose regimen. I certainly wouldn't recommend this drug to anyone without caution. I am 100 percent acne free on my entire body, with extremely minimal side effects thus far. I am maintaing that condition so far on 20mg's every 4 days. I bet based on how my body feels, that I could do it on even less. I intend to try and prove that point in the very near future. Dr. Plewigs study suggest some individuals maintain an acne free state with as little as 2.5mg's twice a week. To be fair, it is working for people with mild to moderat acne, I don't see a lot of low dose reports for really bad cystic acne. This drug completely cleard up my nasty oil acne riddled skin in one month. I am blown away. I had to take in 4 different studies which I printed out and show my Derm before he settled down to the idea of low dose. Now he seems to be fully on board with the idea. We could do American acne sufferers a big favor if we would all do the same thing. Educate them thar Doctors as to what the foreigners are up to with this controversial drug called Acctutane. Some Doc's may listen.

Well, enough conjecture for tonight.

Ps. I would rather take this drug for 8 years safely and remain acne free, than taking high dose for 6 months and possibly suffering from side effects for the rest of my life. However there are no real long term studies on low dose Accutane either. It could be just as risky.

Best Wishes
LowTane
14 Mar 2009
Brand:Sotret
Weight:90Kg = 200lbs
Sex:Male
Age:48
Dosage:20mg every 4 days

Well Chooch, I am only guessing here...but I don't think lifting weights will increase testosterone levels much. But what the hell, it couldn't hurt to try it out. Now the supplements, thats not a bad idea. Hopefully whatever you choose will not contraindicate with the Accutane. I am able to get around the damped libido effect with an adjusted mental attitude.

Shidoshi, you couldn't be more correct about helping Accutane therapy out. The modern industrial diet has provided us with many new diseases. One look at nature and we can see that proper diet and exercise keeps the animal kingdom acne free. I have cut out soda pop entirely. I have cut processed sugar to the absolute minimum. We are held captive by the shelves at Safeway. Unless you can grow your own food and hunt regularly you are basically screwed where sodium, sugar, cholesterol and fat are concerned. On your pores, mine have been giving up little hard spicules that come out when washing or just gentle rubbing. You may be shocked at just how tight your pores will get. Unless you have taken this drug before. I can't remember if it was you that posted this is your second time on Accutane.

Well good luck all, time for work unfortunately. I will keep plugging away with the lower dose regimen. I intend to go so low my Acne returns. I am flirting with the idea of longterm micro-dose. If I can stay clear on 2mg twice a week like Dr. Plewig's study suggest, I might try it. I have already noticed that 20mg every 4 days instead of every day has improved my libido.

Side effects minimal, definite slight damping of the sex drive. Extemely mild headach once in a while. Lower lip slightly dry. Thats it as far as I can tell...

Still 100% clear, with oil at an absolute minimum with just over 600mgs and only 40 days in........ unbelievable.

Best Wishes
LowTane
19 Mar 2009
Brand:Sotret
Weight:90Kg = 200lbs
Sex:Male
Age:48
Dosage:20mg every 7 days

I am not sure who is following this diatribe, but it is getting a bit thin on content. I will start posting weekly. Its getting too repetitive, all I can say is every day I am still 100% clear. I think this will get interesting again when I have terminated my low dose therapy. I leave you with this summary:

I started taking what is considered low dose Accutane for my size. This was made possible after I lobbied my Dermatologist with no less than 5 different studies on low dose Accutane from several different countries. After I dropped off the material I got a call and he set the dosage along the lines of the average low dose reported in the aforementioned studies. The first month I took 20mgs daily. I had immediate results. I had been given an antibiotic that doesn't contraindicate with Accutane in case the intial breakout was bad. He didn't want to do this at first, but it turns out I didn't need it. Accutane went to work gangbusters. With this dosage I had only some mild side effects. Slightly dampened libido, dry lower lip and an occasional mild headache. After the first month I was 100% clear. I then dropped my dosage to 20mg every 4 days. I remained clear...I then dropped it to 20mg every 7 days. I am still remaining clear at this dosage. This is where I am now.
I will continue my low dose experiment. When I have something to report I will certainly post it. Until then, I can only say you might consider low dosage if you have moderate or maybe even severe acne. You might consider low dosage if you have major oil problems. Hell you might consider low dosage if you have a hang nail......I have to say it has been a miracle for me so far. I fear the high dosage idea and will probably never ever opt for it. Doesn't mean that high dosage hasn't worked for people. It has.. I just believe that it makes permanent side effects even more possible. These are my own personal feelings, like I said, a grain of salt. I know nothing about this drug in all reality. I am just operating on my personal instincts. So, my observations only serve one purpose. They are cathartic for me. It may however help someone to hear someone else's story. Please read read read and get lots of doctor's opinions before saturating your body with this controversial miracle drug called Accutane.

I wish everyone the best.
LowTane
24 Mar 2009
Brand:Sotret
Weight:90Kg = 200lbs
Sex:Male
Age:48
Dosage:20mg every 2 days

Good to hear from you OL, glad all is well. I have nothing major to report, bumped my dosage back up to 20mg every two days instead of 7. This was based on reading the local dermatologists boards and gaining a consensus. Many believe the total cummulative dose is the ticket. Doesn't seem to matter how you get there, as long as you do. Mild side effects and still one hundred percent clear. Still having a small glass of Cab Sauv once in a while. Down in weight as well. Libido functional with slightly diminished drive. Well thats all folks..........

Best Wishes
LowTane
LowTane, Its nice to hear some positive results with low dose accutane. Im kind of in the same boat as you are. Im 22 with mild acne and really oily skin. Ive tried all the anti biotics/topicals and even ran a course of accutane at 80mg a day for 5 months back when i was 15 when i had it severe. Worked great and was clear all the way up to 07. Now i have the stubborn mild breakouts again that wont go away. I have been using the regimen sense i started breaking out again back in early 2007. It has been working ok but not enough and i really dont want to keep putting benzoyl peroxide on my face for the next 10-20 years. So i decided to go on low dose accutane at 20mg a day sense im not severe and dont want all those nasty side effects i got with the really high dose. Right now im on day 11 and so far so good. Maybe a little bit of an initial breakout but not bad and hoping it wont get worse. Im planning on running this dose for 8-10 months and then maybe cutting it back to 10 mg a day for 2-4 months or maybe even less. These studies of people running ultra low dose has me very interested as i might be a canidate if this second treatment does not allow complete remission. I will keep in touch with my progress.
In summary:

The purpose of this board was to explore the results of using low dose Accutane (Isotretinoin) over a longer period of time than normal therapies with high doses used in a shorter period of time. After becoming desparate with Sebaceous Hyperplasia (enlarged over active oil glands) and mild Rosacea I began reseaching the web heavily and discovered some studies in foreign countries that showed the efficacy of lower doses of Accutane. Why go with lower dosages? To minimize side effects, long term and short term. The end result desired? To go into long term remission for Acne and Sebaceous Hyperplasia. Here is where the debate begins. Some studies have shown significant remission rates with lower dosages. The United States is furthest behind in this type of therapy. Just talk to your Dermatologist and see..... The rule of thumb in this country is "higher dosages = longer remissions and/or possible cures". Individuals have reported the return of their acne with high and low dosages. Other individuals have reported cures and long term remissions with both high and low dosages. We have all heard time and time again that everybody is different. Even though we are of the same species. Its true, drugs seem to effect people differently. I am opting for the lowest dose possible and still maintain an acne oil and rosacea free face. So far I am running perfect, first on 20mg a day and now 10mg a day. I will try to lower the dosage again upon my next appointment. My American Derm is suprised and mildly shocked at the overwhelming positive effect low dosages are having on me. I am 200 pounds. I have referenced links to different studies on Accutane therapy at pubmed and medscape. Talk to your Derm and show them the studies if they are not already enlightend to low dose Isotretinoin therapies. Best of luck....

PS. No matter how I try to explain the positive effect this drug has had on my life it will be understated. I am ecstatic. I have regained my life for the first time in years. I say this knowing that the longterm problems some individuals talk about where this drug is concerned could still be waiting for me somewhere up around the bend.

LT

Disclaimer: Accutane can be a very dangerous drug for some people. I believe this with all my heart. I don't wish to talk anyone into using this drug. Do your homework, consult multiple doctors. And never, ever self medicate off the internet. To many items need monitoring with monthly blood tests to take a risk self medicating. Read about all the possible side effects this drug can cause. At any dose this drug causes birth defects. Remember, what works for one person may be a catastrophe for another.
Hi! I have read all of your posts (thank you for doing this!)
I have mild-moderate acne and rosacea, and though not an extreme case, my skin condition is fairly resistant to all acne/rosacea treatments. - and despite over a decade of trying to eradicate my acne, it still persists.
I started accutane today - after much deliberation - I am 130 lbs, 24 year old female, taking 10 mg a day to begin at breakfast. Admittedly, I was (still am...) extremely nervous to take the pill! - even at such a low dose. I was wondering if I could share my experience on this thread, as the days progress? I probably won't post everyday, but I think that it would help me to be able to communicate freely with someone who is doing the same thing as me.
Also - with all your extensive research, did you find anything relating to possible brain alterations and low dose accutane? Or, even at higher doses, in general?

Thank you :)
Hello!

Summary: Low Dose Accutane for Acne Vulgaris and Rosacea

I am a 49 year old 200lb male and I have been on what is considered (for my body weight anyway) low dose Accutane since February of 2009. I have dual maladies, I am blessed with Rosacea and Acne Vulgaris. Due to the nature of my job I am constantly under fluorescent lights and speaking in front of groups of people. Both Rosacea and Acne look even more hideous under these type of lights. My appearance was affecting my job in a most profound negative manner. I had been aware of Accutane for 20 years, or since its inception into the Acne family of drugs worldwide. I always feared Accutane from day one. One day in desperation I once again began researching this controversial drug and found a study done in Israel on low dose therapy. Hmmmmm!!! I said. I decided I had to try this approach.

I began this treatement in Feb 2009. 20mg daily was prescribed only after convincing my Dermatologist with a barrage of worldwide studies in the efficacy of low dose therapies for certain Acne and Rosacea conditions. Please consult Pubmed and Medscape for all the ammunition you will need to create a portfolio for your Dermatologist. Be prepared for apathy from your Derm over internet research. Make sure you let them know that you have legitimate studies from government reporting sites done by actual researchers. The USA is woefully behind in the low dose approach with this drug. So much so that it is considered off label treatment when other than the prescribed high dose regimens are applied. Have sympathy for your Doc, they want to keep their licenses.

Anyways, I started on a higher dose than I wanted to because my Derm was a little skeptical. I gradually reduced that dosage over time and began to just tell him how much I was taking and he would look at the results and tell me to stay at that dosage for X amount of days. I would ignore him and lower the dosage again. Next appointment same routine. I am now trying just 10mg every saturday. I will let you know how that works for me.

My treatment thus far has been one hundred percent amazing. My life is so much better that I cannot express it in words. My oil is controlled and my pores have close up. Some pores were so damaged from years of popping and picking that they didn't close all the way. So I still have a few big pores in a several areas. I could probably finish the job with some laser type therapies that my Derm and I have discussed once I get off the drug.

So in short low dose Accutane has worked wonders for me. I have Zero side effects that I can detect. It has been like taking a vitamin pill. It is a shame we are in danger of losing this drug. In light of recent events and lawsuits drug makers are re-thinking their bottom lines. Roche has quit selling it, and a few drug makers say they will continue. So for now it appears we can still get Accutane. It is a shame that low dose therapies were never really explored in the good ole USA.

In closing: This drug, like all drugs has side effects. Different people respond differently. If you have excess oil, mild Acne or Rosacea or both, think about low dose. It might be your ticket. However, there is always a risk with any drug.

Best Wishes
LowTane ;)
Tourista, did you create a portfolio of studies as I suggested? Take in actual documentation and ask what their opinon of the study is......Pubmed and Medscape have plenty of studies on Low Dose therapies... If you didn't try this approach, give it a try and see if that helps. Also, what are your symptoms? Do you have cystic acne? Mild oil? What exactly. It could have affected their decision. You have to sell the low dose idea to American Derms.


Best Wishes

LT
[QUOTE=LowTane;4045543]Tourista, did you create a portfolio of studies as I suggested? Take in actual documentation and ask what their opinon of the study is......Pubmed and Medscape have plenty of studies on Low Dose therapies... If you didn't try this approach, give it a try and see if that helps. Also, what are your symptoms? Do you have cystic acne? Mild oil? What exactly. It could have affected their decision. You have to sell the low dose idea to American Derms.


Best Wishes

LT[/QUOTE]

Yes, I did take your advice and printed out the studies - although there are these studies, the Derm told me that the dosage amount is not approved by the FDA and that if he was to prescribe me the accutane it would start at 40mg, to 60mg, than to 80mg.
My acne is a combination of cystic, blackheads, whiteheads, etc. I have oily skin. Tan skin.
I've had acne for over 20 years and am at the age where it scars and creates pits permanently. Even my mildest acne :(
I also have uneven blotchy skintone and enlarged pores. I noticed that after the acne has gone the red marks are still existent and do not fade.
All this going on with my face has affected me emotionally and socially.
Still here.....

I am currently taking 10mg once every 2 weeks, so far so good. I am looking for the bottom here. Still no acne.... however Rosacea flushing is a little worse. Looks like mild sun, no papules or bumps. I don't think I can get much lower. Loving the low dose oil control.....

Best

LT
Well hello everybody, or anybody who happens to come by. It all started Feb 2009. I got tired of antibiotics and went complaining to a dermatologist. I expressed my desire for a low dose alternative to the usual high dose therapies employed typically in the United States for a drug called Accutane (Isotretinoin). I started on 20mg daily for a couple of months and then started tapering the dosage down over the next 4 months. I have mild Rosacea and Sebaceous Hyperplasia (tons of oil basically) and have no signs or symptoms as of this writing. I just quit Accutane, I will be getting some laser treatmens next week and I had to be off the Tane. I have been quit for about one month. It will now be interesting to see what happens. I have an open invitation to come back to my Derm and start low dose again. So..... the clock is ticking. I will let you know when the Sh#$ hits the fan..
Hi All,
I was on accutane, (Roaccutane as its called in Australia) 11 years ago, back when i was in high school. I cant remember the dosage that i was on, but it wasnt a low dose. It did the job, cleared my skin up great, how ever, im now starting to get rosacea, would say its mild, just the red face, cheeks and nose. Its not mild to me of course the constant blushing is so hard to live with. Im wondering if accutane, my have triggered this and or now could even be the cure. I'm wondering if a low dose my help.
When my skin flares up it is oily, which i guess shouldnt be happening, but maybe its my bodys way of fighting back.
I guess im asking has anyone taken a low dose to help with rosacea (red face, cheeks, nose and ears)
And has anyone had there symptoms return, 11 years later?
Thank you.
Hi,

I have just started accutane (was on a standard dose aged 16 - 60mg daily I think). Worked to clear my cystic acne but still suffer mild/moderate acne. Just started another low dose course but after just 2 days at 20mg I have experienced significant facial flushing. It's really depressing me as I thought I would avoid this dreaded side effect at such a low dose. I've skipped a day and intend on perhaps taking another 20mg pill tonight but fear that the reaction will continue. Did you experience a worsening in your rosacea (not sure if this is rosacea but I expereienced the same thing on many topical treatments) at the beginning of your course? I know 10mg daily is often used to TREAT rosacea so really didnt expect this so early on. Any advice/words of encouragement would be much appreciated. Also I switched from Differin to Accutane almost immediately so dont know whether this would be a factor, and have been drinking a fair bit.

Regrds,

Tom
Tommy, I don't know if this helps or not. I experienced quite a few facial flushing episodes when I first started Accutane. They went away. My face still has a slight weathered glow of very light red on the cheeks. It appears like mild sun exposure. The biggest thing for me was that the pustules and infections caused by Rosacea were gone completely. Many Rosacea sufferers report that there is a magic dosage that works for Rosacea. Usually lower than the amount required for severe acne. I was looking for the dosage that bordered acne and Rosacea symptoms. 10mg every other day is where I ended up for the bulk of my treatment. I am 200 pounds and somewhat sensitive to drugs. Again, time is the factor here. The longer I stayed on the low dosage the more stable my symptoms became. Everyone seems to have different reactions to different dosages of this drug. You could ride it out a little, pick your dose and stick with it and see what happens. I started higher than I wanted and continued to taper it down over time. My goal was to find the lowest dosage that would keep my Acne and Rosacea in check. Since you have taken this drug before you proabably remember it takes time for you to stabilize. I wish you the best of luck.

LT





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