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[QUOTE=ADHDMOMOFTHREE]I have had ADHD my whole life. I am a 31 yr old military mother of three. I have never been on medication for it before. My ADHD seems to have gotten worse with every child I have had. I don't know if it is a chemical thing or if the added responsibility has just made it harder to cope. I finally decided to take a stand and get on something to fix it. I started for the first month with Straterra 120mg because it is not a stimulant. (I sleep about 4-5 hours per night due to insomnia and did not want to add to it by taking a stimulant.) Straterra didn't do anything but make me throw up about 2 hours after i took it. No change in my attention span at all, however, it did help me sleep better at night. So my doctor switched me to Concerta 36mg. I have now been on it for 2 1/2 weeks and so far it's not doing anything during the day. And when i get home at night and it wears off, the Mr. Hyde to my Dr. Jeckel comes out!!! I am gritting my teeth in anger at the dumbest little things. I am yelling at my husband, throwing things, and pitching absolute fits over nothing. I am so mean since I started on it. I told my doctor and he said that it takes a month or so to level out in my system. Has anyone else had this effect with Concerta, and if so, does it go away? I am thinking of trying out Adderal instead. Any thoughts???[/QUOTE]

From what I've read, this can happen with any stimulant, which Concerta is. The "leveling out" is merely your brain's ability to adapt to the chemical, usually by shutting down some of it's own stimulating abilities. Downregulation of brain receptors is common when taking a psychoactive drug over an extended time. Bad thing about that is that the brain becomes more dependant on the drug for normal functions and also eventually builds up a tolerance to the effects over time.

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