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My IBS did improve within about a week of being totally off the Opana. I hadn't been on the OpanaER for very long- just a few weeks, but my doctor weaned me down with the immediate release. I had no withdraw symptoms because I also use hydrocodone in my treatment plan. (Norco)

Like I said, I never put two & two together, and am only recently realizing the correlation after seeing that other people had bad GI symptoms while on Opana.

I can only tell you that every LA med I had tried throughout the years really, REALLY did a horrid number on me, so now I take only the immediate release meds with my treatment plan and I am able to get good pain coverage without the horrid side effects. I am able to function as a mom, wife & human being again. :)

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