It appears you have not yet Signed Up with our community. To Sign Up for free, please click here....



Addison's Disease Message Board


Addison's Disease Board Index


Cushing's syndrome is a hormonal disorder caused by prolonged exposure of the body's tissues to high levels of the hormone cortisol. But mine was low. Of course it was only one reading. Sometimes called "hypercortisolism," it is relatively rare and most commonly affects adults aged 20 to 50. An estimated 10 to 15 of every million people are affected each year.

Symptoms vary, but most people have upper body obesity, rounded face, increased fat around the neck, and thinning arms and legs.
No thinning on arms and legs. Fat all over.Children tend to be obese with slowed growth rates.
Other symptoms appear in the skin, which becomes fragile and thin. It bruises easily and heals poorly. Purplish pink stretch marks may appear on the abdomen, thighs, buttocks, arms and breasts. The bones are weakened, and routine activities such as bending, lifting or rising from a chair may lead to backaches, rib and spinal column fractures.
Haven't noticed anything here.

Most people have severe fatigue, weak muscles, high blood pressure and high blood sugar. Irritability, anxiety and depression are common.Now, while I don't know about SEVERE fatigue, I'm tired all the time the rest is sure true. Not sure about the blood sugar. Have been tested last summer for diabetes and came out fine. So they say. lol

Women usually have excess hair growth on their faces, necks, chests, abdomens, and thighs. Their menstrual periods may become irregular or stop. Men have decreased fertility with diminished or absent desire for sex. Can't really say any of this is true either. Certainly not my monthly. My sex drive is gone tho. (I'm a girl). :)


Sometimes other conditions may be associated with many of the symptoms of Cushing's syndrome. These include polycystic ovarian syndrome, which may cause menstrual disturbances, weight gain from adolescence, excess hair growth and sometimes impaired insulin action and diabetes. Commonly, weight gain, high blood pressure and abnormal levels of cholesterol and triglycerides in the blood are associated with resistance to insulin action and diabetes; this has been described as the "Metabolic Syndrome-X." Patients with these disorders do not have abnormally elevated cortisol levels.
Found this paragraph interesting tho....................
[i]Cushing's syndrome is a hormonal disorder caused by prolonged exposure of the body's tissues to high levels of the hormone cortisol. [/i][b]But mine was low. Of course it was only one reading. [/b][i]Sometimes called "hypercortisolism," it is relatively rare and most commonly affects adults aged 20 to 50. An estimated 10 to 15 of every million people are affected each year.

Symptoms vary, but most people have upper body obesity, rounded face, increased fat around the neck, and thinning arms and legs. [/i][b]No thinning on arms and legs. Fat all over.[/b][i]Children tend to be obese with slowed growth rates.
Other symptoms appear in the skin, which becomes fragile and thin. It bruises easily and heals poorly. Purplish pink stretch marks may appear on the abdomen, thighs, buttocks, arms and breasts. The bones are weakened, and routine activities such as bending, lifting or rising from a chair may lead to backaches, rib and spinal column fractures.[/i][b]Haven't noticed anything here.[/b]

Most people have severe fatigue, weak muscles, high blood pressure and high blood sugar. Irritability, anxiety and depression are common.[/i][b]Now, while I don't know about SEVERE fatigue, I'm tired all the time the rest is sure true. Not sure about the blood sugar. Have been tested last summer for diabetes and came out fine. So they say. lol[/b]

[i]Women usually have excess hair growth on their faces, necks, chests, abdomens, and thighs. Their menstrual periods may become irregular or stop. Men have decreased fertility with diminished or absent desire for sex. [/i][b]Can't really say any of this is true either. Certainly not my monthly. My sex drive is gone tho. (I'm a girl). [/b]


[i]Sometimes other conditions may be associated with many of the symptoms of Cushing's syndrome. These include polycystic ovarian syndrome, which may cause menstrual disturbances, weight gain from adolescence, excess hair growth and sometimes impaired insulin action and diabetes. Commonly, weight gain, high blood pressure and abnormal levels of cholesterol and triglycerides in the blood are associated with resistance to insulin action and diabetes; this has been described as the "Metabolic Syndrome-X." Patients with these disorders do not have abnormally elevated cortisol levels.
[/i][b]Found this paragraph interesting tho....................
Hi,

Oh...I hear the torture in you that I hear in myself. I am not diagnosed yet and I am going nuts trying to figure out what is wrong with me. I am currently awaiting more test results and another visit to the doctor. I empathize!!

Cushing's is very much like other endocrine diseases in that everyone responds to hormonal abnormalities differently. Few ever have all of the symptoms of any disorder but that shouldn't rule out the disease. Also, it takes many years (many!) for full blown Cushing's to arise in most people, while some never get the whole picture of symptoms. So most start out with just a few symptoms and add on more with time. Symptoms may also come and go as cortisol levels can vary or be cyclical in the early stages of the disease. Along those same lines, dexamethasone suppression testing that turns out normally can be very misleading. Most in the early stages of the disease WILL suppress normally and their doctors will send them away. You really need a doctor who understands this and has a high index of suspicion, if it is indicated.

There are quite a few Cushies who have true Hashimoto's which appears before Cushing's, I'm not sure if there is a relationship there or not. So, you don't have to have central hypothyroidism for the diagnosis. Some have concurrent sex hormone alterations due to FSH/LH abnormalities, some have GH deficiency, some don't...everyone is different with this one.

You may have misunderstood me in my first post...it isn't what your cortisol is at any given moment in time, it is what it is OVER time. (Hence the 24 hour urine collections that Chris suggested) Quite a few cushies WILL have very low morning cortisol levels as a part of the "loss of diurnal variation" I mentioned but then later in the day have very high levels. Don't let your cortisol level throw you.

PCOS can indeed cause quite the constellation of symptoms but it should not cause the fatigue you mention, unless you have undiagnosed diabetes (which you said you had been worked up for and didn't have) or uncontrolled high blood pressure (which would be a result of obesity, not PCOS directly). MANY women are misdiagnosed with PCOS when they have Cushing's, because the elements of PCOS (and metabolic syndrome X) are a PART of the big picture of Cushing's.

That said, I certainly hope this isn't what is wrong with you. I hope you have an issues that is more easily addressed. But...if you don't look, you wont find a problem and this is something to just consider.

Good Luck to you and know you are not alone in your frustration!
Sadie
Awwww, thanks Sadie. It is just SO frustrating! Trying to argue with a doctor is like beating your head against the wall. I mean, what can you tell them 'Hey, I'm talking to all these women on a board and well, you are just wrong!'. :) I'm not the kind of person to think I have everything, I know I'm not just making things up.

By they way, the doctor did call back interestingly enough. Wants to check my glucose over 3 different draws. My labs have been coming back with my glucose in the upper range and once over the upper range.

The fun never ends, does it..............................................

I also don't think I have the symptoms of adrenal fatigue - given what I've read. I'm truly more convinced their is a thyroid problem - and maybe a diabetes problem. I do have high blood pressure which I'm on meds for. And I'm in the obese range - 256 by last weight. Yuck! For someone who was 140 just 6 years ago, this is tough.

Hang in there yourself and thanks for the prop of support,
Traci





All times are GMT -7. The time now is 12:46 AM.





2019 MH Sub I, LLC dba Internet Brands. All rights reserved.
Do not copy or redistribute in any form!