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Addison's Disease Message Board

Addison's Disease Board Index

Good points Cloud2. I believe the calculation for cortef dose is weight x 0.11 mg/lb; so an average 150 lb person would take about 15 mg/day.

Unfortunately, all the factors and more that Cloud2 mentioned make a specific number impossible to calculate. Cortisol levels fluctuate hourly, daily, weekly and monthly in a "normal" person, so all we can do is approximate what our bodies need...taking more during stress times.

It is probable that osteoporosis is not only related to higher cortisol dose but also the subsequent lack of DHEA due to adrenal shut down. DHEA is a steroid that acts to build bone and muscle and the fact it is missing in Addison's helps promote bone loss.

I should note that osteoperosis is a long term effect and has no symptoms until bones break.

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