It appears you have not yet Signed Up with our community. To Sign Up for free, please click here....



Addison's Disease Message Board


Addison's Disease Board Index


Yes. ACTH is the hormone secreted by the pituitary that tells the adrenal gland to release cortisol. When the pituitary senses there is enough cortisol, then it stops secreting ACTH. ACTH comes out in pulses - so if there is a high stress situation and you need the stress hormone (cortisol), the pit will release a lot of ACTH to stimulate the adrenals. It is a feedback loop.

Abnormalities happen when ACTH is secreted when there is no stress and then cortisol is raging around all the time which then leads to damage. Sometimes the Cortisol will just secrete all by itself - so if cortisol is high and ACTH is low, odds are issue is adrenal, not pit. If ACTH is high, issue is pit, generally, or ectopic if super high. This is not always true however as I had normal ACTH and my issue was pituitary.

The two should be tested together, don't you think?





All times are GMT -7. The time now is 03:06 PM.





© 2020 MH Sub I, LLC dba Internet Brands. All rights reserved.
Do not copy or redistribute in any form!