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Addison's Disease Message Board


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31 yr old recently took Adrenal Stress Index due to chronic fatigue.
Cortisol levels severly depressed.
[U]7am[/U]- 5 nM (ref. value 13-24 nM)
[U]11 am[/U]-<1 (ref. value 5-10 nM)
[U]4 pm[/U]- <1 (ref. value 3-8 nM)
[U]11 pm[/U]- <1 (ref. value 1-4 nM)
DHEA- Pooled value- 2 (ref. value 3-10)-- showed zone 7- Adrenal Fatigue.
Insulin- fasting <3 Normal
post-prandial <3 Depressed.

I've been prescribed 5 mg Hydrocortisone to take once at 7 am, noon, and 4 pm as well as 5 mg DHEA once daily.
I was wanting to start out conservatively because I'm afraid of adverse side effects. Has anyone had any side effects from Hydrocortisone and DHEA? Weight gain, hair growth, etc?

Anyone been successful in treating Adrenal Fatigue??
Hi Nicole. I'm 30, and have also had CFS/FM for 8 years, and recently diagnosed with Adrenal Insufficiency, via an insulin tolerance test.

How severe is your CFS? How are you feeling before you've started the Cortef? Are you able to cook, clean, go to shops etc, or much worse?

They are extremely low results.. so it seems you may benefit alot from the Cortef i'd think.

Have you tried other adrenal supps first? Licorice root is what i started on when i had severe adrenal symptoms. It really picked me up in a big way, but its effect wore off and i needed more until i got bad enough to need hydrocortisone (cortef). I haven't been on it long and am on a bit of a rollercoaster, but so far it's provided some benefits such as really helping my constant hypoglycaemia, stopped the freezing cold inner shakes i was having, etc. I have periods of feeling alot better, but so far the're only small windows, I have a long way to go yet.

The DHEA can and does help alot of people with AF/AI/Addisons. I have severe liver detox impairment so dhea causes some side effects for me, but not for most. I may try it in cream form next instead of tablets/lozenges to bypass the digetsive tract.

Let us know how you are going. ~Chris.


[QUOTE=nicoleaua;3770799]31 yr old recently took Adrenal Stress Index due to chronic fatigue.
Cortisol levels severly depressed.
[U]7am[/U]- 5 nM (ref. value 13-24 nM)
[U]11 am[/U]-<1 (ref. value 5-10 nM)
[U]4 pm[/U]- <1 (ref. value 3-8 nM)
[U]11 pm[/U]- <1 (ref. value 1-4 nM)
DHEA- Pooled value- 2 (ref. value 3-10)-- showed zone 7- Adrenal Fatigue.
Insulin- fasting <3 Normal
post-prandial <3 Depressed.

I've been prescribed 5 mg Hydrocortisone to take once at 7 am, noon, and 4 pm as well as 5 mg DHEA once daily.
I was wanting to start out conservatively because I'm afraid of adverse side effects. Has anyone had any side effects from Hydrocortisone and DHEA? Weight gain, hair growth, etc?

Anyone been successful in treating Adrenal Fatigue??[/QUOTE]
Thank you for your reply. I have a low energy level every day- I don't have the energy for cooking or shopping but I manage to go to work. I'm hoping that the medication will level me out before I get to the point of shutting down completely. Today was the first day taking hydrocortisone and DHEA so I'm anxious to see how I feel and whether it makes a difference. My doctor told me that my levels were too low to try licorice. She said that it only works when your cortisol levels are slightly depressed. It gives me hope that you've had some windows of improvement :) Hang in there...
[QUOTE=nicoleaua;3771633]Thank you for your reply. I have a low energy level every day- I don't have the energy for cooking or shopping but I manage to go to work. I'm hoping that the medication will level me out before I get to the point of shutting down completely. Today was the first day taking hydrocortisone and DHEA so I'm anxious to see how I feel and whether it makes a difference. My doctor told me that my levels were too low to try licorice. She said that it only works when your cortisol levels are slightly depressed. It gives me hope that you've had some windows of improvement :) Hang in there...[/QUOTE]

hi nicoleaua. i live in atlanta also but cannot find a doctor who will perscribe me hydrocortisone. my saliva tests were almost identical to yours. has the protocol that you are on helped you? please let me know the name and number of the doctor that you see for your adrenal fatigue. i am so desperate to feel better. thanks
3x5mg + 5mg of DHEA is very conserative. It will take the DHEA several weeks to kick in, and the hydrocortisone will take some time as well. Many people don't see an improvement for many months.

That dose may be too low to recharge your system and you may need higher doses to get feeling normal and then cut back a bit.
[QUOTE=Sypher7;4037540] 9 months later on HC and I'm still wrecked unfortunately :( For some reason even though HC has helped the awful state I was in (crashing and going to ER every week for 6 weeks during august/september last year), im still absolutely ruined with crushing fatigue and brain fog every day. In fact my cognitive dysfunction / brain fog is worse than it's ever been since being on HC.

[/QUOTE]

You may be suffering from yeast/fungus infection in your intestines. This often happens after repeated antibiotic use and hydrocortisone promotes the growth of fungus as well. The solution is to go on a zero sugar diet for at least 2 months, and get a prescription for an antifungal called Nystatin. You must take the pills, not the liquid (which contains a lot of sugar) and take the pills for at least a month probably two months.

If you have a pituitary problem associated with adrenal insufficiency then you may need to go on growth hormone (symptoms include, brain fog, muscle/joint pain, a form of depression called apathy, memory/concentration problem and a weird thing where you think something and then before you can say it out loud you forgot what you were thinking).

In addition, everyone taking hydrocortisone is also deficient in DHEA. I would begin taking 25mg per day. DHEA will improve your immunity and breathing and thus increase your exercise capacity; it also has several other beneficial effects on your body (DHEA is the most abundant hormone in a normal human body).

You should also begin taking 50mg of zinc, 2000 iU of vitamin D, 1mg of folic acid as well as a calcium/magnesium supplement. All of those will act to improve your immunity.

It took me a year to find out HC wasn't doing it for me and I only discovered by accident that Nystatin could help along with growth hormone and DHEA.

What was the cause of your need to take testogel? I would suggest that you should be taking the T shots instead. The gel is not always reliable and low testosterone could be contributing to your symptoms.
hydrocortisone is a great drug for addisons. I was recently diagnosed with addisons and trust me it sucks. just make sure you take ur meds everyday otherwise your adrenal fatigue will catch up with you.





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