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Pernicious Anemia?
Aug 6, 2005
I'm having problems with my sense of taste as well as sensation. I also get twitches and feel short of breath quite often. Pernicious anemia sounds like it can cause symptoms like these, but last time my b12 level was taken (8 months ago) I had a B12 that was normal. My MCHC level was high, however, and I've read that this can be due to having larger cells caused by pernicious anemia. Is it possible to have pernicious anemia with normal b12 levels?
[QUOTE=rocketsurgeon]I'm having problems with my sense of taste as well as sensation. I also get twitches and feel short of breath quite often. Pernicious anemia sounds like it can cause symptoms like these, but last time my b12 level was taken (8 months ago) I had a B12 that was normal. My MCHC level was high, however, and I've read that this can be due to having larger cells caused by pernicious anemia. Is it possible to have pernicious anemia with normal b12 levels?[/QUOTE]
Yes pernicious anemia is caused by the body's inability to utilize the B-12. It is like having a tank full of gasoline. If the mechanism between the storage tank and the engine is broken, the tank ful of gas is not doing any good.
"My MCHC level was high"
Can you please tell me what MCHC is. ??? I'm stuggling with symptoms that match Pernicious Anemia and Thyroid disease which both run in my family. When my B12 was tested last, I was told it was in the normal range. I could not convince them to do a shillings test. I have recently been diagnosed with Hashimoto's thyroiditis. The symptoms of both diseases are much the same. Since taking meds for low Thyroid my labs have improved to what is considered in the normal range, but I still have symptoms. Now I'm back to wondering if Pernicious Anemia may be the cause of my fatigue, foggy head, and tingling sensation in my hands and feet. Any information would be appreciated. Thanks!
[QUOTE=rocketsurgeon] last time my b12 level was taken (8 months ago) I had a B12 that was normal. My MCHC level was high, however, and I've read that this can be due to having larger cells caused by pernicious anemia. Is it possible to have pernicious anemia with normal b12 levels?[/QUOTE]
Is MCHC like MCV (Mean Corpuscle Volume)? Mine was high too, indicating B12 or folate def., so docs checked those and they were normal. B12 was "high", but symptoms continued and I got worse. Methylmalonic acid test (can be serum or urine) revealed my B12 deficiency. Homocysteine testing is also sometimes used to Dx B12 problems. I guess sometimes there's a problem with the "transportation" system in the body where the B12 in the blood doesn't get where it's needed--in the cells/nerves/brain (B12 isn't used in the blood).
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