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In August I had a sudden drop in iron. From a relatively healthy 13.8 HgB to 5.8. Hemocrit 21, Ferritin >1. Long story short, never found a cause, went on ferrous gluconate, tolerated it well, felt tons better. Went to generalists, specialists, had all the tests, no cause, sometimes this stuff happens. Anyway, went down on iron supplements and just went off three weeks ago. Just had labs and iron went down from 15.8 to 13.8 and hemocrit 45 to 37. So from high to normal range but I am being a worrywart and wondering, is that drop going to continue? Is that a big drop for three weeks? Anyone here have experience with this? Thank you! :confused:
You might want to get checked for an enzyme deficiency called G6PD deficiency. They used to think it only occurred in males, but newer studies and DNA testing have shown that it's possible for females to also be affected and not just carriers.

Most people with G6PD deficiency never know they have it unless they are exposed to foods, chemicals or medications that can cause oxidative stress. The red blood cells are destroyed rapidly and you can have a severe sudden drop in hemoglobin. The main triggers include fava beans, mothballs, quinine-derived drugs. If you do a search you'll find lost of information.

It's good to get testing after an episode of hemolysis like you experienced so that you can avoid the contraindicated substances in the future. The blood test needs to be done at least 6-8 weeks after the drop in RBCs...newer red blood cells have higher levels of the enzyme and will skew the results.


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