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Hi vanbill,

Thanks for your comment.

The MCV has been increasing over the past 10 years or so, from 93 to 95 to 96 over a period of several years and then up to 99 within a month of the last blood draw. So even if not officially macrocytic (based on some reference ranges) yet, the RBC size is definitely trending that way.

Yes, I've been supplementing with B12 and folate for over a year, which would explain the high blood levels of them. So given that I am supplementing, I am not deficient in those nutrients, yet the RBCs are getting larger. That is what does not make sense to me.

An update that I did not post before is that I have low ferritin (14), despite supplementing with iron for over a year as well. Serum values of iron, TIBC, % saturation, and transferrin are all normal (very near the mid range) though, so I don't understand why ferritin is low.

The quest continues.

And I do greatly appreciate your input. Yours was the probably the most knowledgeable response I've seen from a message board. :-)

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