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Hello,

I am so confused about my lab results, and if anyone here has experience with the specifics on differentiating deficiency anemia from chronic disease anemia, please help...

I almost began iron and bought floradix(sp?), but now reading online, I'm confused/ scared whether it's clear iron deficiency or disease triggered anemia.

Some sites say ferritin differentiates the two anemias, but my results are borderline:

They say normal/high ferritin says disease anemia, does this mean end of normal range, does it include any normal range(even bottom)?

They say low ferritin expresses true iron deficiency, does this have to be below the bottom of the normal range or can it be normal bottom of range?

Results:
Ferritin- 25 (15-292)- NORM
Iron- 44 (35-150)- NORM
Iron Binding- 363 (250-450)- NORM
Transferrin Iron Saturation- 12 (15-50)- LOW
Serum Transferrin- 284 (200-360)

WBC- 7.3 (4-11)
RBC- 4.56 (3.9-5.4)
Hemoglo- 12.8 (11.7-15.5)
Hematocr- 38.8 (35-47)
MCV- 85 (80-100)
MCH- 28.1 (27-33)
MCHC- 33 (31-36)
RDW- 13.1 (<16.4)
Platelets-311 (150-400)

Thank you for reading!
Cat
I found this on labtestsonline a while back. I had the same questions too. (TIBC refers to iron binding capacity)



IDA = TIBC high and FERRITIN low
ACD = TIBC Low or normal and FERRITIN Normal or high


Are you considering taking iron because the transferrin is low?

"Transferrin is a protein that may decrease during any inflammatory process and is referred to as a negative acute phase reactant. Chronic inflammation, infections, and malignancies may cause changes in transferrin levels."


"Transferrin saturation is a calculation using the iron test result and the TIBC or UIBC results, representing the percentage of the transferrin that is saturated with iron."


So I wonder if it represents how much iron is in your body because the rest of your labs look fine. Hope this helps.
hi,
that's the problem with my results:
my ferritin is LOW NORMAL
my iron saturation(transferrin saturation) is LOW
my TIBC is MID-NORMAL
my serum iron is LOW NORMAL
my serum transferrin is MID NORMAL

I don't seem to fit any of these:
IDA = TIBC high and FERRITIN low
ACD = TIBC Low or normal and FERRITIN Normal or high
Confused?

I was considering taking iron, as the FERRITIN is LOW NORMAL, but am worried/wondering whether this is IDA or ACD, and if it's safe to take iron not knowing which anemia it is?
Actually, my [B]ferritin [/B]is on the low-normal range, my serum transferritin level is mid-normal. But, I have transferrin(iron) saturation at 12%- LOW-, how can this not be abnormal in some way?

I'm wondering what the difference is between [B]Ferritin[/B], [B]Serum Transferrin[/B], and [B]Transferrin(iron) Saturation?[/B]

I don't know if I have anemia symptoms, but am not feeling healthy...weak muscles are a predominant issue, and I have restless legs for certain, which I've had for a long time, before ever testing iron levels. Actually based on my CBC, I would have never tested iron panels(this is the first time), but I had a hunch and asked the DR...

I've seen people post about iron deficiency [B]without [/B]amenia, with normal hemoglobin/MCV. So perhaps that might be my issue...

I am planning to see DR soon. I began on a low dose on iron anyway, if I feel worse, I'll stop. I wish my case was straight forward, but nothing in my life ever is *SIGH*
From what I have researched, iron deficiency is low ferritin. Ferritin is the iron you have stored in your body. When you don't have enough serum iron, it then starts using the ferritin or the iron stores. When that gets used up, you are anemic. Your ferritin is well within the normal range. A lot of people would kill for a ferritin of 25!

I myself had normal HGB (12) but my ferritin was 9 so before I was checked for ferritin, my doctor told me that I should not be having anemia symtpms UNTIL she checked my ferritin. I was sooo sick, I couldn't get off the couch. I was soo dizzy, my heart was racing and I was out of breath. Mine is at 27 now and boy, do I feel great!

All the other blood tests you referenced will tell the doctors why you are anemic if you are. It will give them an idea of weather you are bleeding, if your bone marrow is making the proper proteins, etc.

I know what you are saying though but doctors will look at your tests and see that you are in the normal range and say there is nothing wrong. I think it might benefit you to look at past blood tests for comparison and see if there are any big changes. And keep in mind that some of your tests are near the lower end of the range so if you do get tired in the future or have other anemic symptoms, you might have an idea why. I don't think there is anything wrong with taking responsibility for your own health.

And do your research on taking too much iron. There are consequences for that too.

[QUOTE=mochicat;5020153]Actually, my [B]ferritin [/B]is on the low-normal range, my serum transferritin level is mid-normal. But, I have transferrin(iron) saturation at 12%- LOW-, how can this not be abnormal in some way?

I'm wondering what the difference is between [B]Ferritin[/B], [B]Serum Transferrin[/B], and [B]Transferrin(iron) Saturation?[/B]

I don't know if I have anemia symptoms, but am not feeling healthy...weak muscles are a predominant issue, and I have restless legs for certain, which I've had for a long time, before ever testing iron levels. Actually based on my CBC, I would have never tested iron panels(this is the first time), but I had a hunch and asked the DR...

I've seen people post about iron deficiency [B]without [/B]amenia, with normal hemoglobin/MCV. So perhaps that might be my issue...

I am planning to see DR soon. I began on a low dose on iron anyway, if I feel worse, I'll stop. I wish my case was straight forward, but nothing in my life ever is *SIGH*[/QUOTE]





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