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Well I can say that I've been on 38.5mg of effexor for a week, switching from 200mg zoloft and I can tell a major difference. First of all I don't beat myself up as much as I used to about my body and I don't consitantly worry about what people will think of me or my weight (social anxiety). Now I just try to be the best I can be and I know that my personality will shine through for me. I can also wake up in the morning so much easier! I couldn't get awake until about noon on the zoloft. None of my passion for life has gone away, I can concentrate better. The only negative side effect I noticed was that I do crave sweets alot more then I did on the zoloft, which my mom also noticed switching from celexa to zoloft that she didn't crave sweets as much on zoloft. But I also know that it's a craving from the meds and that I'm not really hungry and the feeling goes away after awhile. I'm not sure how I feel about taking it twice a day, not sure why my doc didn't call me in the XR version??? Another side effect that is starting to go away, sometimes it kind of feels like I've taken sudaphed. u know like the buzz you sometimes get from sudaphed only it's not as strong. I'm sure that feeling will go away with use.

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