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I went straight from Lexapro after 6 weeks (it was not working for me) to Zoloft and immediately noticed an improvement - mainly for depression. I've been on the Zoloft (100 mg) for a couple months now and the only side effect has been sexual, but had the same problem with Lexapro and Paxil. I've never felt like a zombie or drugged on any anti-depressant. Sometimes I wish it was more sedative. That's just me. Everyone has different reactions to AD's.
Hope you see an improvement soon. They always say it takes 4-6 weeks to feel full effect.
JB





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