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Hello everyone. I have GAD. I had very good success managing my GAD for 12 years on Paxil (with increasing dosages along the way). I went from 20 mg to 60 mg over those 12 years. I've recently gone through a high stress period of my life and my anxiety was coming back. I successfully weaned down the paxil and transitioned to Lexapro, although I had huge emotional upheaval during this switch. I did okay on Lexapro for about 5 months, but it never completely seemed to work (I was at 20 mg). I was also having more frequent headaches and leg aches/restless legs on the Lexapro. So, 12 days ago my dr. switched me directly to Zoloft, 100 mg.

I guess my issue is, naturally, anxiety that the zoloft won't work either. I had 3 days of increased anxiety but mucked it out because I remember the same situation when starting paxil. I have had a few moments where I felt calm & happy but it's an up & down thing. I can manage, and have xanax as needed, but I just want to feel like myself again!

Those of you that have switched to Zoloft- how long was it before it really worked? I know when I started Paxil it was literally 8 weeks, with one dosage adjustment until I felt back to normal. When switching SSRIs does it also take that long to feel the effects? I have been seeing a therapist for a year, which has been very helpful but I know I also need meds.
Has it occurred to you that these drugs just simply don't work over the long term? These drugs affect serotonin in the brain and anxiety has absolutely nothing to do with serotonin and there is not a doctor on the planet that can prove that it does. It's all theory and conjecture. Try asking a doctor to prove you have a serotonin deficiency and they will go ummmm, wellllllll! You are on SSRI's and Benzo's? Anxiety is a learned habitual negative thought process pattern that set's off the adrenaline gland. Drugs will never cure that. It just amazes me how many people are been misled about all this. I had a doctor tell me once "well, you have to believe the drugs are going to work in order for them to work" I said "seriously ..... you have to be kidding me". That's why in studies, these drugs work no better than a placebo (if the patient doesn't know they are getting a placebo). Big Pharm has tried to hide these studies from the public because of the billions of dollars made by the pharmaceuticals, but the studies are out there. I had a deadly reaction to an SSRI and I'm lucky to be here today. I used to have anxiety, but I don't suffer from it anymore and I didn't need drugs to get there. The only anxiety I would probably experience today is reading about all the people who are on these dangerous meds and not getting better and getting frustrated that they just don't get it. We have truly become a medication nation. If you want permanent freedom from anxiety, you will have to deal with it at it's core and not cover it up with meds. It can be done, I did it, I had no choice .... I couldn't take the meds that they claim will cure you! Good luck and I wish you all the best!

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