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[quote]Originally posted by Just Barb:
[b]I keep forgetting important dates and meetings. I left the boys at tennis the other day!! I just wish I could be normal like everyone else. [/b][/quote]

Just Barb,

Hi! I noticed that you take levoxyl for hypothyroidism. I do too. And, though I am only 27, I also experience brain fogginess, forgetfulness, and trouble concentrating. This is hard on me as an intellectual and just as a young person!

Recently, the New England Journal of Medicine posted a study at [url=""][/url] which states that people on thyroid replacement hormone, which is usually just levoxothyrine(t4), have improvements in the symptoms that you're having when t3(Cytomel or from Armour Thyroid) is added.

Here's an easy-to-understand condensation of the study from [url=""][/url]

February, 1999 -- The February 11, 1999 issue of the New England Journal of Medicine

The article is titled:

"Effects of Thyroxine as Compared with Thyroxine plus Triiodothyronine in Patients with Hypothyroidism"

How the study was conducted

Essentially, they took a group of 33 people who were hypothyroid, either due to autoimmune thyroid disease, or removal of their thyroids due to thyroid cancer. All the patients were studied for two five-week periods. During one five-week period, the patient received his or her regular dose of levothyroxine alone. (Levothyroxine is the generic name for the brand names such as Euthyrox, Levoxyl, Levothroid and Synthroid.) During the other five-week period, the patient received levothyroxine PLUS triiodothyronine (T3.) (Note: In the U.S., the brand name for T3 is "Cytomel." ) In the T4 plus T3 phase, 50 g of the patient's typical levothyroxine dose was replaced by 12.5 g of triiodothyronine (T3). A variety of blood, cognitive, mood and physical tests were conducted at various stages of the testing.


From the standpoint of physiological effects, the differences between pulse, blood pressure, reflexes and a variety of other functions for T4 alone, versus T4 plus T3, were very small. Blood pressure and cholesterol in fact dropped slightly on the T4 plus T3.

Where the results were dramatic were in mental functioning. Patients performed better on a variety of standard neuropsychological tasks on the T4 plus T3. Patients' psychological state also showed improvement on T4 plus T3.

At the end of the study, patients were asked whether they preferred the first or second treatments. 20 patients said they preferred the T4 plus T3 treatment, 11 had no preference either way, and only 2 preferred T4 only. The 20 patients who preferred T4 plus T3 reported that they had more energy, improved concentration, and just felt better overall.

The researchers determined that "treatment with thyroxine plus triiodothyronine improved the quality of life for most patients."

You may want to talk to your dr. about this study and adding t3 in an effort to improve your symptoms. With luck, you might be able to get off of antidepressants. My goal is to find a way to stop using them by the end fo the summer!


p.s. feel free to email me with questions at [email protected]

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