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I am 24yr old male.
I am getting married this friday!
I usually take 15mg of methotrexate per week. I've been on methotrexate for a year and a half. I have drank on average two beers per occasion every other week or so for several months now...all liver function tests have always been great. I was supposed to take my weekly mtx dose today. I really would like to have some alcohol for my bachelor's party this wednesday, so i am considering skipping the mtx for this week. I know that there is a long half-life for mtx...but i figured it would be best for my liver to skip the mtx for a week.

What are the ramifications of missing the meds for a week?

Is there considerable danger of liver damage in I have six or seven beers on wednesday?

I am not asking for permission to start being irresponsible on a regular basis--just this once.

-thanks for any suggestions

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