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Blood Tests
Jun 21, 2012
I am having some aches and pains. My hands hurt, my ankles hurt, I am not sure what is going on.

I had a work up with blood and here is what was found:

CBC = Normal

CRP Inflammation 8.2 (0.0 - 8.0 mg/L)

ANA Screen by EIA <1.0
Interpretation: Negative <1.0

Rheumatoid Factor <7 (0 - 14 IU/mL)

Sed Rate 15 (0 - 20 mm/h)

SSA (RO) Antibody IgG 2
Reference range: 0 to 40

SSB (LA) Antibody IgG 0
Reference range: 0 to 40
Unit: AU/mL


The only thing that was slightly high was the CRP and having said that.. my CRP in the past was 9.4 and that was due to an IgA Deficiency I have according to my endocrinologist. So 8.2 is a lower result. Normal RF and negative FANA, Sed Rate is normal, Sjogrens tests normal.

Does this seem to rule out rheumatic disease? My primary thought so. I was wondering what everyone here thought?

Re: Blood Tests
Jun 21, 2012
At this point, no one would commit to a diagnosis of a rheumatological condition, but with your inflammatory CRP a little high, if your symptoms persist or worsen, I would get retested in 6 months or so. Frequently, rheumatic disease symptoms precede any lab evidence of what it is. A sed rate of 15, although in normal range, is borderline, in my opinion, as most people run sed rates of 1-5. That will fluctuate and will tend to be higher when you are having more symptoms. You didn't mention how long this has been going on, so if it is pretty new, it may take awhile for it to become clear. I would consider your family history and if there is a positive family history of inflammatory arthritis and your symptoms persist, pursue trying to get it figured out. In the meantime, an anti-inflammatory medication like ibuprofen or naproxen may be helpful in relieving your symptoms.
Re: Blood Tests
Jun 21, 2012
Thanks, you guys, so much for your awesome posts.

Yes, the orthopedic doctor took an x - ray of my ankle and it was entirely normal, the joint was fine. He said I do not have osteoarthritis and that is when he thought I should get inflammatory arthritis looked at.

Yes, I totally know about IgA Deficiency and the automimmune connection. My biggest thing is gut issues. I get inflammatory reactions with my gut all the time. It comes and goes but I never have been diagnosed with UC or Crohn's because that is not my pattern. I get this diffuse inflammation that just comes and goes that's apparently due to my zero IgA deficiency gut trying to deal with the lack of IgA and clearing out pathogens, etc.

I believe that is why my sed rate and crp has always been high normal. There was a time though about five years ago my sed rate was elevated to like 30 but no other test was abnormal so they watched it. Eventually it climbed down. They related it to IgA Def.

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