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High Cholesterol Message Board


High Cholesterol Board Index


I just came across this abstract from the Annals of Internal Medicine. According to it, no-flush preparations of OTC niacin contain no free nicotinic acid and should not be used in niacin therapy.

[url]http://www.annals.org/cgi/content/abstract/139/12/996[/url]
Lenin, i got my niaspan thru a prescription, it costed me $38. I didn't know niaspan could be purchased otc. I started taking it but stopped bcuz of the asprin situation. Besides the flushing started with the niaspan.
[QUOTE=jtu91952]. . . I didn't know niaspan could be purchased otc. I started taking it but stopped bcuz of the asprin situation. Besides the flushing started with the niaspan.[/QUOTE]jtu, what did you find about the interaction of Niaspan and aspirin that caused you to stop taking it? When I looked up the interactions, it just said that "aspirin may cause blood levels of niacin (also referred to as "nicotinic acid") to be increased. This interaction is poorly documented and is considered minor in severity." So as I see it, we are just getting more bang for the buck by taking aspirin with the niacin. (Maybe that is why I'm able to get adequate cholesterol control with only 750 mg. Enduracin, whereas the usual therapeutic dose for a sustained release niacin is 1000-2000 mg.)

The flushing usually goes away as your body gets used to it. I had minor flushing for just the first week. However, I understand that for some reason it is often recommended to take Niaspan before bedtime. And were you able to start out with just 250 mg.? (The only places I've seen it listed, 500 mg. was the lowest amount.) With the Enduracin I'm taking (which is an OTC sustained release), the manufacturer recommends that it be taken with meals, and that one start out with only 250 mg. daily and build up from there. Those precautions greatly diminish the flushing and itching.





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