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High Cholesterol Message Board


High Cholesterol Board Index


Thanks Jacqueline,
It also seems that what SOME tests view as Lp(a), others (presumably the VAP) see a grouping of things like Lp (A1), Lp(A2), and Lp (A1+B) ...confusing and DISTINCTLY unamusing:D:D! So therefore your test probably was measuring only a fraction of what mine were.

Here's a study indicating that Lp(a) is quite dangerous ...of course people undergoing angiography are not exactly a sample of men on the street. Probably a GOOD sample might remove something like 40, 50, or 60% from all those percentages. I guess the biblical "Mark of Cain" was nothing more or less than the Lp(a) gene!

[QUOTE]Lipoprotein (a) [Lp(a)] levels have been correlated with angiographically defined coronary artery disease (CAD). Pattern of Lp(a) distribution in various racial groups is different. To study this relationship in Indian patients, plasma levels of Lp(a) and other lipid values were assessed in 101 patients undergoing coronary arteriography. Lp(a) concentration was higher in CAD group (n = 77) compared to normal coronary artery group (n = 24) (26.83 +/- 22.09 mg/dl vs. 15.07 +/- 14.61 mg/dl, P < 0.05). Lp(a) values had graded association with CAD. [b]In Lp(a) quartile of < 5 mg/dl, 66.7% patients had CAD; in Lp(a) quartile of 5-25 mg/dl, 69.0% had CAD; Lp(a) quartile of 26-75 mg/dl, 87.5% had CAD; and in Lp(a) quartile of > or = 76 mg/dl, all patients had CAD.[/b] High density lipoprotein (HDL) cholesterol was higher in the normal coronary artery group as compared to CAD group (45.25 +/- 8.26 mg/dl vs. 41.83 +/- 16.47 mg/dl; NS). In HDL quartile of < 35 mg/l, 88.9% patients had angiographically defined CAD. Plasma values of total cholesterol, triglycerides (TG), apolipoprotein-A1 (Apo-A1), apolipoprotein-B (Apo-B), low density lipoprotein (LDL) cholesterol, LDL/HDL cholesterol ratio and Apo A1/B ratio were not significantly different in the groups with normal coronary arteries and CAD. Our results indicate that the measurement of Lp(a) provides a better marker for predicting the presence of angiographically defined CAD as compared to traditional measures.[/QUOTE]

It would seem that, since 3/4 of the group had CAD, then those levels below 75% (Lp(a) < 25 and some undefined amount above 25 that is healthy but somewhere between 26 and 75 (could it be BROADER???) one crosses the "extra" CAD incidence. So it seems that chosen level of 30 as the upper normal of my test might be pretty close to true (using tha standards employed in this study.) Oy, that correlation of 100% CAD with Lp(a) over 76 mg/dL is a DOOZY of a finding though, isn't it?





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