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High Cholesterol Message Board


High Cholesterol Board Index


joel,

HDL's are SO hard to get up...it's almost always a genetic thing. A low HDL is always a risk factor in itself, perhaps one of the most important.

Two things I have found to work:
[B]ALCOHOL[/B], but MORE than 16 ounces a week. For a guy your size something like 3 drinks a day (12 ounces of wine) would do the trick.

[B]NIACIN[/B] supplementation in therapeutic doses...think 500- 2,000 mg/day depending on tolerance.

I find hard exercise, whether strength or aerobic, to be USELESS with regards HDL.

You can try daily lecithin and/or fish oils, maybe you'll have some luck but both are beneficial even if they don't touch your HDL levels.

Your diet and weight seem fine.
WHackedback,

If your primary problem is a low HDL and you want to try niacin and cut back on your pravachol, I recommend ANY straight niacin, not niacinamide, nor slow or extended release... or any doodads. See if you can tolerate the flush from it. If not, then you;ll have to consider some sort of timr release version...but the straight niacin works best.

Make sure to test your liver regualrly if taking naiacin especially if taking a statin too.
[QUOTE=whackedback]I'm in the same boat.... What brand of niacin supplements do you suggest? I'd love to reduce my daily intake of Pravachol (80 mg).

wb[/QUOTE]

Just ordinary immediate-release niacin is more effective at raising HDL than the time-release versions, and it's probably safer too. I'm not taking statins, but I have been taking niacin (250mg four times a day) for at least 15 years or so. I believe it has done wonders for my HDL, and I have had no problems tolerating it.

In your case, since you are on a statin, you need to be more cautious when using niacin, and your doctor should be aware that you are taking it. However, if your problem is mainly a low HDL, I really don't see the sense in increasing the Pravachol to 80mg. Perhaps you would be better off with just niacin. Another option which may be more beneficial than Pravachol would be Advicor. Advicor is a statin/niacin combo all in one pill. I'm surprised that we haven't heard more about Advicor on these boards.
[QUOTE=ARIZONA73]Wb,

I just saw from one of your other posts that you are also diabetic. Ordinary niacin can sometimes raise blood sugar in diabetics. One alternative which you may also want to consider is flush-free niacin, also known as inositol hexanicotinate. Studies have shown that this form of niacin has little or no impact on blood sugar. The usual dose can be anywhere from 1000-3000mg a day. It is also supposed to be much easier on the liver.[/QUOTE]

Arizona,

DId you ever try Inositol Hexanicotinate?

I've been taking it for several months now - but only about 500-750mg/day. The first time I tried it my lips tingled and my throat got scratchy, and I still feel uncomfortable trying to get up to 1000mg+.

So far it hasn't had much effect on my HDL...

HubbleRules
:cool:
[QUOTE=HubbleRules]Arizona,

DId you ever try Inositol Hexanicotinate?

I've been taking it for several months now - but only about 500-750mg/day. The first time I tried it my lips tingled and my throat got scratchy, and I still feel uncomfortable trying to get up to 1000mg+.

So far it hasn't had much effect on my HDL...

HubbleRules
:cool:[/QUOTE]

Hubble,

Yes, I have tried it before, but I have never used it long enough to measure its effects on my HDL. I have always gone right back to using the 250mg immediate-release niacin I get from Puritan's Pride. Old habits die hard, I guess, especially since this form of niacin has worked rather well for me over the years. I know they say that inositol hexanicotinate is supposed to work just as well, but I can't personally vouch for that. My father, who is diabetic, has been taking inositol hexanicotinate for several years now. His HDL is currently running about 80. Several years ago his HDL was usually in the 45-55 range. Of course, it is difficult to tell exactly how much of an effect the niacin has had on his HDL, since he has made other changes over the years as well. For example, 15 years ago he stopped smoking. I noticed that his HDL numbers were generally the lowest during those years when he was still smoking. So I believe the fact that he stopped smoking probably had a positive effect on his HDL.

P.S. I never did notice any side effects from inositol hexanicotinate. I've never experienced even a slight flushing sensation, even after a 650mg Twinlab inositol hexanicotinate capsule.
Or inositol nicotinate...really the same thing as the hexanictotinate. Like Iron oxide and Diferrous Trioxide are the same. :D

I view the inositol nicotinate as yet another slo release formulation. Same goes for pricey Niaspan, and a poly-glycol Slo-Niacin that I am taking now.
ALL are gentler than straight nicotinic acid (niacin) flushwise because they don't release a big pile of niacin at once but that's why they are more dangerous...they expose the liver to niacin for much longer. In my best Italian, it's a "Catcha 22"!

Whether thy are called extended release, sustained release, slow acting, all day, etc., you are talking about variations on the same theme.

I;ve just had my blood drawn this morning and I am hoping that 2 weeks on the SLO-NIACIN hasn't messed up my ALT and AST!





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