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High Cholesterol Message Board


High Cholesterol Board Index


Just got back from my physical...
TC 143
HDL 36
Trigs 89
LDL 104
and because of the higher LDL Doc wants to up Provachol from 10 mg to 20. I have tolerated the 10 mg dose all right...anyone familiar with possible unusual side effects of this particular statin??
The high LDL is unusual for me, and I think that it might reflect an abnormal period of fried food consumption just prior to the test rather than a regular reading. Would such a diet show up immediately in a lipid profile??
Thanks in advance
Grandpa,

Pravachol is a pretty weak statin and you are on a low doseage.

Your numbers are quite good and I'd say stay on the 10's UNLESS you have proven coronary artery disease. If you do have considerable plaque that has caused you problems, the a goal of much lower LDL's is worth striving for and an increase to 20 mg. is certainly warranted.
Thanks Lenin...I have had two angioplasties since 1998...am on Tricor, Toprol and the Provachol, so I'll give the 20mg a try. My diet is usually exemplary but I fall off the wagon once in a while and hopefully that was the cause of the high LDL...
[QUOTE=GranpaMcCoy]Just got back from my physical...
TC 143
HDL 36
Trigs 89
LDL 104
and because of the higher LDL Doc wants to up Provachol from 10 mg to 20. I have tolerated the 10 mg dose all right...anyone familiar with possible unusual side effects of this particular statin??
The high LDL is unusual for me, and I think that it might reflect an abnormal period of fried food consumption just prior to the test rather than a regular reading. Would such a diet show up immediately in a lipid profile??
Thanks in advance[/QUOTE]

Yes, the diet could play a role in the higher test results especially prior to the test. I would think, and so do experts that you should concentrate more on raising the HDL. Statins are not know to increase HDL, and in fact can lower them.
Repeated post
Statins have been shown time and time again to increase HDL!
All it takes is a look at the data!

Specifically for Pravachol:


Dose Response of PRAVACHOL
Once Daily Administration

Dose....... Total-C.. LDL-C HDL-C TG

Placebo (N=36) -3% -4% +1% -4%
10 mg (N=18) -16% -22% +7% -15%
20 mg (N=19) -24% -32% +2% -11%
40 mg (N=18) -25% -34% +12% -24%
Mean Percent Changes From Baseline After 8 Weeks*

Granpa,

Something is wrong with your numbers:
143 = 104 + 36 + 18 doesn't compute. (The 18 comes from 89/5) One or more of the numbers is reported wrong. Is it conceivable you have switched the triglycerides with the LDL? That would give a much closer 146 total. Also a MUCH better LDL of 89.

Suffice to say, with your heart condition an LDL of <100 is a minimum for you with < 70 an ideal goal. (I finally got my rejoicable 69! :p )
I agree. It looks like the LDL would be 89. I think the first three numbers are correct and someone calculated the LDL incorrectly. The 143 would also be correct. I know my lab sends the report without calculating the LDL and leaves that up to the doctor.
I get the TC as 158 if the other numbers are right.
Well, that is confusing...I thought that I had copied down all the numbers correctly...will have to check again....good eyes, Lenin, and thanks once again to all.





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