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High Cholesterol Message Board


High Cholesterol Board Index


Dave,

I judge a triglyceride level of 365 in the presence of an HDL of 35 to be QUITE severe and an agent that attacks triglycerides directly seems to be very important.

An increase of 28% in the AUC (area under curve, or a measure of total drug exposure) of the statin doesn't seem too significant and perhaps might lend itself to an effective reduction of the Zocor.

The main effect of the fibrate and the fibrate-stating combo, as others have said, is to the liver and thus measuring liver functions AND CPK for muscle damage is important...have them run at 30 days and then maybe 90 days later.

If you want to give it a try WITHOUT the TRICOR, why not do a month with no alcohol or sugar and see what you get? But familial hypertriglyceridemia is a tough nut to crack.





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