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High Cholesterol Message Board


High Cholesterol Board Index


Niacin Flush
Nov 8, 2006
I am 30 and have had high cholesterol numbers, which are now under control from Vytorin, but my last 2 VAP tests showed my lp(a) levels at 22, where normal is under 10. After the first high level results I began takin slow release niacin (inositol hexaniacinate) but after taking 500mg for 6 months it had no impact on the lp(a) numbers. My doctor now recommended that I take the regular B3 niacin starting at 25mg and working my way to 1000mg per day.

I have had panic anxiety for the past 5 years and do not do well with new medicines or weird feelings so am not looking forward to the flush. With the slo-release I would ocassionally get a slight tingle in my face, but nothing that I would say was a full on flush.

My doctor recommended taking an adult aspirin 1 hour in advance and then taking the niacin with a meal, and after that I could expect a 20 minute or so flush.

I am hoping someone can describe to me their experiences with starting with a low dose and working their way up. Also how long after taking the niacin does the flush start.. is it minutes later, or hours... I really just want to feel comfortable with taking it and understanding how I am going to feel and in what time frames.

Also if anyone else has had high lp(a) numbers, please let me know how niacin helped.

I appreciate any help.
Re: Niacin Flush
Nov 9, 2006
master,

I too suffer with a sky high genetic Lp(a). My experience is that NOTHING affects it much with the possible exception of HUGE quantities of booze and even then only slightly. Niacin works a bit but only a for few percent change.

I have tried at least 10 times to titrate my doseage of regular niacin up to therapeutic levels. By the time I reach 100 mg., the flush is very uncomfortable...at 250 it is nearly unbearable and at 500 mg, it is dangerous. I found NO effect from the gradually increasing dose...in no way did it help acclimate myself to it. I just CANNOT take this crap in anything approaching a therapeutic dose.

If the same happens to you, get back on the slow-release and give the leftover straight niacin to your doctor. :D
I take 500 mg. and occasionally 750 mg. of slow release before bedtime WITH 2 adult aspirin. The flush is very slight and only if I stay awake for an hour.


I won't comment much on your Lp(a) because there are at least 3 different standards of normalcy floating around. BUT if you got 12 on any standard that topped out at 10, you are pretty close to normal. I wish I could say that.

The way that I look at it is that I have the risk factor of high Lp(a) and there is bupkis that I can do about it. What I CAN do is minimize all the other risk factors...so the niacin is for raising my HDL and the Lipitor is for shrinking my LDL and triglycerides. Exercise for heart workouts, and weight control to minimize bodyfat, fish oils for whatever they do :D, and daily aspirin to prevent clots, and good BP control round out the picture.

All I can do is HOPE my genetic Lp(a) doesn't kill me all on its own.
Re: Niacin Flush
Nov 9, 2006
[QUOTE=master44]I am 30 and have had high cholesterol numbers, which are now under control from Vytorin, but my last 2 VAP tests showed my lp(a) levels at 22, where normal is under 10. After the first high level results I began takin slow release niacin (inositol hexaniacinate) but after taking 500mg for 6 months it had no impact on the lp(a) numbers. My doctor now recommended that I take the regular B3 niacin starting at 25mg and working my way to 1000mg per day.

I have had panic anxiety for the past 5 years and do not do well with new medicines or weird feelings so am not looking forward to the flush. With the slo-release I would ocassionally get a slight tingle in my face, but nothing that I would say was a full on flush.

My doctor recommended taking an adult aspirin 1 hour in advance and then taking the niacin with a meal, and after that I could expect a 20 minute or so flush.

I am hoping someone can describe to me their experiences with starting with a low dose and working their way up. Also how long after taking the niacin does the flush start.. is it minutes later, or hours... I really just want to feel comfortable with taking it and understanding how I am going to feel and in what time frames.

Also if anyone else has had high lp(a) numbers, please let me know how niacin helped.

I appreciate any help.[/QUOTE]

There is a NO FLUSH NIACIN that can be purchased at your local health food stores or from Vitiman Co's.

This I have found to be excellant, No flush at all, It is compounded with a substance that eliminates the FLUSH. Don't even bother with the slow release, it isn't worth it. I have been on this for almost year with absolutely no --- none--- zero flushes.

What have you got to lose? Nothing !!!!





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