I may be somewhat of an analomy here, but I've been taking 10 mg of Crestor daily for two years with no problems whatsoever. My total cholestoral has gone from 250 to 176. I also take 100 mg of the CoQ10 supplement at the same time, which I understand offers protection against muscle damage, etc.
I hate taking drugs, but my dr. advised there is evidence of plaque in my arteries (which can also affect memory), so I consider myself very lucky not to experience side effects.