It appears you have not yet Signed Up with our community. To Sign Up for free, please click here....



High Cholesterol Message Board


High Cholesterol Board Index


Hello all,

Well, after approx. 6 months of niacin therapy, I got new blood results in. Somehow, my HDL has gone down on 500mg Niaspan daily.

HDL started off at a paltry 29. After around 3 months, it went up to 33-34 (forget exactly), and now 3 months later it reads 28.

My LDL is slightly worse too, at 132 (it's normally 110-120ish), but I chalk that up to increasing my fish oil to the 3.5-4 gram range as an experiment to lower triglycerides/improve LDL particle sizes. But neither budged and it seems instead all I did was add about 10 pts to my LDL. And my LDL size seems locked into the A/B pattern, no matter what diet/exercise/niacin/fish oil/vitamin D changes I made.

As to reasons why Niaspan didn't help... still a bit clueless. One possibility is that I recently started taking it around dinner time, instead of right before bed, as I felt I was having some sleeping problems. I recently found out I may have acid reflux, which could explain why niacin right before bed would be a bad idea.

Another possibility as to why my HDL went down is: the Niaspan didn't really help to begin with, and my temporary increase to the 33-34 range would have occurred with or without being on Niaspan. My HDL range tends to be 28-34ish, so there is no guarantee that Niaspan originally rose my HDL at all.

I speak with my cardio next week, and we'll have to go over new options. Perhaps raising Niaspan to the 750mg-1000mg range would work. If not, I'm sorta out of options for improving HDL (that I'm aware of). Low-dose statin might be a last resort, just to lower LDL as much as possible, since my HDL is so crummy.

I've also investigated other reasons for low HDL, such as hormone levels, thyroid, vitamin D (currently at a nice 56), but they all came back fine.

I'll also ask my cardio about Apo-A1 and perhaps get that tested separately. There is the rare chance it's not quite as terrible as my HDL is.





All times are GMT -7. The time now is 05:12 AM.





© 2021 MH Sub I, LLC dba Internet Brands. All rights reserved.
Do not copy or redistribute in any form!