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High Cholesterol Message Board


High Cholesterol Board Index


I think that there are probably a multitude of factors involved here, and it is difficult to single out or pinpoint any one of them as being THE telling factor. The human body is a very complex mechanism, with a dizzying amount of chemical reactions occurring at all times. I do feel, however, that dietary influences are also involved, and that when the diet is adequate, and essential nutrients are readily available in sufficient quantities, then there is a greater probability of continued good health. If the diet is of poor quality, or the intake of essential nutrients is sub-optimal, then our body's natural chemistry becomes skewed, setting in motion a series of chain reactions which can manifest itself in many ways, including any number of changes pertaining to blood-lipids, etc.

Our current epidemic of type 2 diabetes and obesity are two good examples of diet related disorders, and I believe that to a large extent, the same is probably true for atherosclerosis. Therefore, what we need to do is to determine the root cause of heart disease, and then work from there. But so far we haven't done that. We appear to be more concerned with uncovering risk factors, and developing various drugs to couteract them. This whole thing just keeps snowballing, and in essence all we are doing is treating an underlying symptom.

So, how many risk factors are there already? Let's see now. There is total cholesterol, low HDL, high LDL, high triglycerides, homocysteine, lipoprotein(a), CRP, VLDL, high blood pressure, and now LP-PLA2. That's 10 right there. Have I missed any others? This is getting ridiculous. Every time they discover another potential risk factor, they answer the call by developing some new drug. This is enough to drive anybody crazy.


P.S. Incidentally, I am inclined to agree that inflammation risk markers may in fact turn out to be the most valid benchmark for developing heart disease. If cholesterol alone was the culprit, then blockages would more randomly occur throughout our bodies. But it doesn't. Pauling and Rath also pointed this out, and stated that the deposition of plaque inside the artery is the body's way of repairing a crack or tear in the artery wall--sort of like the way a scab forms over an open wound.

[This message has been edited by ARIZONA73 (edited 07-20-2003).]
[quote]Originally posted by ARIZONA73:
[b]So, how many risk factors are there already? Let's see now. There is total cholesterol, low HDL, high LDL, high triglycerides, homocysteine, lipoprotein(a), CRP, VLDL, high blood pressure, and now LP-PLA2. That's 10 right there. Have I missed any others? [/b][/quote]

I'll add genetics as a possible risk factor.

All things suggest that all these are indicators. What is the root cause? Not absolutely known yet. We do know there are cultures that have extremely low incidencs of CAD. Even knowing this, there is no definitive factor identified that wraps up exactly why. For any one avenue there is proof and then there is contradiction to that proof.

You do what you can given the information available.



[This message has been edited by pcovers (edited 07-20-2003).]





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