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High Cholesterol Message Board


High Cholesterol Board Index


Hi Shine4U,

I hear your problem! My cholesterol was just checked everything turned out okay except for my Triglycerides (402!!!). That is after taking Simvastatin to lower them. Your LDL (which is your bad cholesterol is very high). My doctor wants me to start tricor to lower by trig's also, but I am kind of scared to take both a fibrate and a statin together. My Trig levels have been in the 400's for years and so far no problem, but my Dr. said there is a high risk for pancreatitus if my trig level doesn't come down. I also am not overweight. 5 feet and weigh about 120 lbs. Unfortunately, my body fat content is 36. I also love meat, especially BBQ T-bone steak and rib eye. I also drink alot of red wine and I think the combination of both is what is causing the high trig levels. After speaking to my Dr., a fibrate such as Tricor is usually well tolerated and as far as giving up your wine, well, statins do the same thing, they are processed in the liver and I continue to drink alot of it and my liver function continues to remain okay. If you do decide to take the fibrate and drink your wine, don't worry because as long as you are honest with your Dr., he will monitor your liver function. If it comes back bad, you will have to give up one or the other. I think usually your liver functions correct themselves after stopping the medication. I am not a Dr. or anything but just sharing my experiences with you. Stop worrying and try the meds.

missy222
I congratulate you on trying exercise and diet to alter your lipid values. But you do have rather elevated lipid values there, so medication may eventually be needed. Worth trying diet/exercise too though.

A couple of suggestions:

Ask for a VAP, c-reactive protein, vitamin D and homocysteine test from your doctor.

Diet changes -- I know this will sound radical, but for those of you with very elevated triglycerides and wish to avoid medications, pretend you have celiac disease. If you avoid all wheat products, and high carb foods, trigs will go down -- a lot. But you don't have to even be so radical, just reduce wheat and high glycemic foods, and the numbers should improve.

Supplements: Did you mean 9 grams of fish oil, or 9 grams of Omega 3s? As 9 grams of Omega 3s is very high, sort of eskimo levels, and that may compromise your immune system. If you meant 9 grams of fish oil resulting in something like 3 grams of Omega 3, that is fine.

No-flush niacin (Inositol Hexanicotinate) is worthless for cholesterol control. If you wish to try niacin, I advise doing it under a doctor's care, as it can elevate liver enzymes. Slo-Niacin or prescription Niaspan can help you avoid any flush.

If taking vitamin E make sure it contains all forms of E (alpha, gamma, beta, delta) and ideally tocotrienols too. Jarrow makes a 'FamilE' product that may be suitable.

Guggul should be taken under a doctor's care too, as it can interfere with lots of prescription drugs. So just be careful there.

If you wish to avoid medications, yet go the natural route, ask your doctor about red yeast rice. It's sort of a 'baby-dose', natural statin. It does still have some of the same side effects as regular statins (although usually less), so take it with CoQ10 too. But again, I always advise that people do these things under a doctor's care. If your doctor is adverse to diet/exercise/supplements, it may be time to get a new doctor.

Depending on risk factors, prescription niaspan, or a form of statin may be needed too.

Oh, and a previous poster mentioned 'CholestOff' -- I'd avoid it. Plant sterols will reduce cholesterol by approx. 10-15% in some people. But what happens is that the sterols just take the place of cholesterol when forming plaque. And plaque is the real enemy. So it basically just improves your numbers, but doesn't reduce risk of heart disease. Or at least there is no evidence to date it reduces risk.
My trig's were 1,700. Talk about being scared. Crazy thing is that they were 700 and when I got on Niaspan they doubled to 1,700. Im on Trilipix now and prava. The trig's came down by 88%.


[QUOTE=missy222;3933547]Hi Shine4U,

I hear your problem! My cholesterol was just checked everything turned out okay except for my Triglycerides (402!!!). That is after taking Simvastatin to lower them. Your LDL (which is your bad cholesterol is very high). My doctor wants me to start tricor to lower by trig's also, but I am kind of scared to take both a fibrate and a statin together. My Trig levels have been in the 400's for years and so far no problem, but my Dr. said there is a high risk for pancreatitus if my trig level doesn't come down. I also am not overweight. 5 feet and weigh about 120 lbs. Unfortunately, my body fat content is 36. I also love meat, especially BBQ T-bone steak and rib eye. I also drink alot of red wine and I think the combination of both is what is causing the high trig levels. After speaking to my Dr., a fibrate such as Tricor is usually well tolerated and as far as giving up your wine, well, statins do the same thing, they are processed in the liver and I continue to drink alot of it and my liver function continues to remain okay. If you do decide to take the fibrate and drink your wine, don't worry because as long as you are honest with your Dr., he will monitor your liver function. If it comes back bad, you will have to give up one or the other. I think usually your liver functions correct themselves after stopping the medication. I am not a Dr. or anything but just sharing my experiences with you. Stop worrying and try the meds.

missy222[/QUOTE]
Hi MeFrom Here

Why did Niaspan increase your Trigs so much, I thought it was suppose to lower them? That's great that they are down to 180, but what is Trilipix? Is it a fibrate? Now that I have dropped my trigs from 402 to 276 my doctor is not pressuring me to take a fibrate. What a relief!! The only bad thing is that since I have been on Simvastatin my liver enzyme tests are going up and now my doctor is telling me that my kindey function is not quite what it used to be.. Two months ago my kidney function was excellent and now she stated that I have Stage 2 kidney disease. I'm thinking that maybe this statin that I am on is not such a good thing and I am considering not taking it anymore to see if my numbers improve.

Missy 222
I'm not sure why the Niaspan didn't work. Trilipix is a fibrate yes and it's the only one approved to be used with a statin. It can be a little rough with the muscle pain and cramping on both of those , so you have to watch it. But,it dropped mine from 1700 to 180 in 1.5 months if my home test is right (I hope it is). I just hope I can get off the statin or the other one, I don't know how long I can stay on both of them. I would ask your doctor if you can just go on Trilipix by itself a month. But, he may have a reason not too. Trilipix was just approved in Dec. 2008. I go to a University Clinic where they tend to be up on the latest treatments for everything. I hope it works out for you and me both :) The best of luck ! :)) I go back this week to find out where I go from here. Also, trig's are supposed to be 150 or below, at least that is the published guideline.

[QUOTE=missy222;3972758]Hi MeFrom Here

Why did Niaspan increase your Trigs so much, I thought it was suppose to lower them? That's great that they are down to 180, but what is Trilipix? Is it a fibrate? Now that I have dropped my trigs from 402 to 276 my doctor is not pressuring me to take a fibrate. What a relief!! The only bad thing is that since I have been on Simvastatin my liver enzyme tests are going up and now my doctor is telling me that my kindey function is not quite what it used to be.. Two months ago my kidney function was excellent and now she stated that I have Stage 2 kidney disease. I'm thinking that maybe this statin that I am on is not such a good thing and I am considering not taking it anymore to see if my numbers improve.

Missy 222[/QUOTE]
Hi Shine4u,

Nice to hear from you again. You can say I was very surprised when I went for my last Dr.'s visit. Was so glad to see that I dropped my trigs down to the 200's but was shocked that my liver enzymes went up and kidney function level had dropped. Now remind you, I was a healthy person with just a problem with cholesterol, mainly my triglycerides. In the last few months that has completely changed. I feel that this Simvastatin that I have been on for the last couple of years may be doing something to me that is affecting my organs. When I asked my Dr. to quit the statin last week, she pretty much swept my liver enzymes under the rug and said "they are still in normal range". A HIGH normal!!!!! As far as my kidney function level, I went from excellent 2 months ago to Stage 2 Kidney disease!!! What's with that????? I asked what happened to stage 1 and she said it could be from uncontrolled blood pressure. My blood pressure is below normal when I am at home. The only time it goes up is when I have to go in and see her because everytime I do I come home with a new illness!!!! When I went to the pharmacy the other day to pick up my prescription for my statin, I noticed on the side effects and I quote "uncontrolled electrolytes problems may increase your risk for side effects that can result in kidney problems". I am seriously considering stopping Simvastatin, I hate to though because it really worked in dropping my overall cholesterol. Never had a problem with muscle aches or anything else except for this last blood test result. I think the doctors these days are just pretty much pushing pills on you for everything and sometimes that seems so much easier than changing our lifestyles. My doctor told me that statins should be in our drinking water. I don't know anymore what I am going to do. I was suppose to go in this week for another blood test and follow up appt. but I don't think I am going to go. I just need a break from all of this. I hope you follow up though, you will never know if your regimen is working if you don't go. Don't put it off any longer. I know you don't like to go to the Dr.'s either, but it's important. You never know, your cholesterol numbers may just have improved!!

Good luck and let me know what happens!

Missy





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