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High Cholesterol Message Board


High Cholesterol Board Index


Yackedear - The research studies conducted here in the U.S on both INOSITOL HEX and POLICOSANOL do not show any significant results versus placebo. In Europe and So.America they appear to work. This leads me to believe, that the quality of the ingredients in this country are not the real deal. Consumer Labs has conducted many studies on Non FDA approved vitamins, including INOSITOL supplements, and most have failed for lack of correct ingredients. We really don't know what we are really taking. That may be a reason. The last Inositol hexanicotinate (Flush Free Niacin) study showed that after three months at 1500 mg/day no trend for improvements in total cholesterol, LDL-C, HDL-C or triglycerides exist.

Missy - INOSITOL HEX is neither type of Niacin. Not Extended or Immediate release. Niacin is in a class of it's own, hence the name of the substance does not include Niacin. Another form of Niacin is called "Niacinamide".
Niacinamide does not effect the liver at all. It also does nothing for high cholesterol. It works for Acne and Inflammation, but it lacks the vasodilator, gastrointestinal, hepatic, and hypolipidemic effects of Niacin.
Probably the ingredients being used.... Most Policosanol products, probably the same. Keep in mind that MD's and pharmaceutical companies consider Niacin to be one of their own. This limits the quality of products being sold, to be highly inferior to true FDA tested prescription brands. Such as NIASPAN and NIACOR. Weak and aldulterated batches are probably rampant. If medical research states that INOSITOL HEX is junk, and you continue to buy it, the fault is the consumers. You cannot complain to the manufacturer that the pill is not working. NIACIN immediate release and Sustained Release is an exception, because the flush is clearly present, and over 500 research studies proves this. The batches have to be pretty exact.
Plain Immediate Release Niacin and Prescription Extended release NIASPAN will always work. Scientific research has proved this in numerous studies. Physicians prescribe it all the time. No other form of Niacin has proven to be effective.
polacekt;

I also believe they are effective. Your correct about monitoring the liver enzymes. It seems any Suspended Release or Extended release Niacin formulas carries a much greater risk of liver damage than plain Immediate Release. As I mentioned in a previous post, doses as high as 20,000 mg a day of Immediate Release were being researched for Psychiatric Issues, with very few cases of increased liver enzymes. Suspended release has caused actual Liver Failure.
[QUOTE=ACE28;4196889]Plain Immediate Release Niacin and Prescription Extended release NIASPAN will always work. Scientific research has proved this in numerous studies. Physicians prescribe it all the time. No other form of Niacin has proven to be effective.[/QUOTE]

Why do you keep saying this?

This is just pure hogwash.

I go on google scholar all the time, and have seen numerous studies which conclude INH is either as effective, or even slightly more effective, than pure niacin, for stabilizing lipids.





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