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High Cholesterol Message Board

High Cholesterol Board Index

In the latest research study which compares Red Yeast Rice to Pravachol,
data showed that red yeast rice was as well tolerated as pravastatin and achieved clinically significant levels of LDL-cholesterol reduction in a population with previous statin intolerance. The authors said that if red yeast rice was properly regulated to control for potential contaminants and regulate consistency between different manufacturers, red yeast rice may represent an option for these difficult-to-treat patients. The Doctor's in the study said that in the real world, statin-associated myopathy and myalgia is a common and difficult problem for clinicians.
The article also emphasized the fact that pravachol and red yeast rice were also the same in regard to side effects. Almost no muscle related side effects in both groups. The dosage was red yeast rice 2400 mg twice daily in patients who previously discontinued at least one statin, other than pravastatin, because of muscle pain. The studies conclusion were that after 12 weeks of treatment, red yeast rice reduced LDL-cholesterol levels 30% from baseline, from 181 mg/dL to 126 mg/dL, while pravastatin reduced LDL-cholesterol levels 27%, a nonstatistical difference between treatments. Similarly, there were no significant differences observed in changes in total cholesterol, triglycerides, or HDL-cholesterol levels.

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