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Chronic Fatigue Message Board

Chronic Fatigue Board Index

From Dr. Learners site.

"Twenty-five patients with CFS illness were treated orally for 6 months with pharmacokinetic doses of valacyclovir (valtrex) in a formulation to give continuous anti-EBV effective blood levels throughout the day. This is the first time such valacyclovir dosing was given. The trial was approved by the U.S. Food and Drug Administration. Patients were carefully monitored for safety by repeated appropriate blood tests. There were no adverse side effects. Sixteen patients with single virus EBV infection were benefitted, but 9 clinically similar CFS patients with EBV-HCMV co-infection were not benefitted. Valacyclovir (valtrex) in the laboratory is effective versus EBV, but it is NOT effective (active) versus HCMV. Therefore, the results strengthen the need for subset classification and appropriate subset-directed antiviral treatment for CFS illness. This, to our knowledge, is the first successful report of valacyclovir treatment for EBV infection."

"Eleven CFS patients with EBV-HCMV co-infections were appropriately treated according to their prior subset classification over an 18-month period with antiviral drug treatments. All patients were carefully monitored for safety every 4-6 weeks. Valacyclovir for EBV infection and ganciclovir for HCMV infection were used. There were no significant side effects in CFS patients. All 11 CFS patients in this study were significantly improved."
Hi, it's been about 6 months since I last posted here because I have been really out of it with this darn CFS and FMS and Hashimoto's Thyroiditis.

Ten weeks ago I started Valtrex at 3000 mg for the first week and then decreased it to 1500mg per day. The first couple of weeks were great and I felt the best I had in the past 3 years.

Week 3 and on I have just been going down hill. Just had EBV titers retested and they are higher now than they were 10 weeks ago. I also was running a severely high fever and BP was spiked in the extremely high zone. Today is a much better day.

Valtrex is expensive, at around $1000 per month, but insurance is paying. Not sure how long my integrative doc will keep me on this but I really hope it is doing me good and not making matters worse.

I will try to keep you all posted on the AV and my condition.

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