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Next month, I begin the Pegasys/Copegus treatments for my hep c. I am opting for treatment despite the fact my disease is mild right now (fibrosis 1, grade 2 inflammation). First, I haven't had children yet and don't want to pass this on to them when I do. Second, I don't want my liver to get any worse--better to treat now while the disease is mild. I am young and don't want to have this anymore.

Of course, I am afraid of treatment because I have suffered from severe depression since childhood. I am currently on 150 mg of Zoloft and 50 mg of Seroquel. My psych and gastro docs both say that I can and should continue my anti-depressant meds during treatment to prevent the depression from returning. I definitely don't want that to happen.

Is anyone else out there on treatment for hep c and depression? Does the interferon interfere with your meds? Has depression/anxiety returned even though you are still on your anti-depressant meds?

I will be under close supervision by both my docs so if anything comes up, they will either change my meds, or stop treatment of the hep c.

In this case, I know that the cure is worse than the disease, but I am determined to beat this and try to have a long, healthy life. However, this is the first time in my life that I have felt good and am not depressed. I am afraid of that horrible depression returning. But I am just as afraid of leaving the hep c alone to damage my liver and potentially cost me my life.

Any thoughts would be much appreciated.

P.S. Hair loss...how prevalent is it in females being treated with Pegasys/Copegus? I know that should be the least of my worries, but I am a woman after all :) How about weight gain? Do the meds cause weight gain? I have been lucky so far with the anti-depressants...no weight gain! Again, excuse the vanity--blame it on being female.

Thanks.





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