Thanbey, Disregarding the flippancy of your "145" remark, I am trying to follow the guidelins of my gastro, ie; biopsy every 3-5 years. If I have progressed to serious liver damage for whatever reason (alcohol, smoking, or anything else), I would have to cosider retreatment, even though I could not tolerate the pegintron side effects the first time. Maybe pegasys? Anyway, I thought maybe someone has had experience with Fibrospect, rather than a liver biopsy, to determine liver damage...