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When I wrote my first post, my initial guess was either you had a combination IgG or the IgM. But your results wording lead me to IgM.

Was LabCorp the actual lab that did your blood work? Your negative combination IgG result is a good sign. It means at the time of the blood draw, you do not have either type of HSV. How many weeks did you wait post last possible exposure? LabCorp's default test is a non-type specific test (like the one you had). If it's positive, you're retested with the HerpeSelect ELISA test for HSV2. If this result is negative, you're assumed to have HSV1 and no further testing is done. If the result was positive, then your tested again with the HerpeSelect ELISA test for HSV1.

The IgM results are confusing and should be disregarded. The thought is these IgM antibodies show up first on an initial (first time) outbreak. After 6 months they'll dissipate as the IgG antibodies show up and take over and will be with you for the rest of your life to help fight off further infections (which is a good thing). While this thought process is true, it's not true all the time. Meaning, just because you have IgM antibodies, it doesn't mean 100% you be developing the IgG antibodies soon. The IgM antibody is a general purpose antibody and shows up for many other common things. As I mentioned before; A negative results doesn't mean you do not have the virus and a positive results doesn't mean you do.

If you waited at least 12 weeks before getting tested, your IgG result should be accurate. However, for peace of mind, I would get retested with the HerpeSelect brand test at the 6 month mark past possible exposure, it's a type specific test for both HSV1 and HSV2 and FDA approved (which you first IgG I/II test isn't). LabCorp offers HerpeSelect but your doctor needs to request it by Name/code.

DO NOT have your doctor order the IgM test again.
[QUOTE=over21]When I wrote my first post, my initial guess was either you had a combination IgG or the IgM. But your results wording lead me to IgM.

Was LabCorp the actual lab that did your blood work? Your negative combination IgG result is a good sign. It means at the time of the blood draw, you do not have either type of HSV. How many weeks did you wait post last possible exposure? LabCorp's default test is a non-type specific test (like the one you had). If it's positive, you're retested with the HerpeSelect ELISA test for HSV2. If this result is negative, you're assumed to have HSV1 and no further testing is done. If the result was positive, then your tested again with the HerpeSelect ELISA test for HSV1.

The IgM results are confusing and should be disregarded. The thought is these IgM antibodies show up first on an initial (first time) outbreak. After 6 months they'll dissipate as the IgG antibodies show up and take over and will be with you for the rest of your life to help fight off further infections (which is a good thing). While this thought process is true, it's not true all the time. Meaning, just because you have IgM antibodies, it doesn't mean 100% you be developing the IgG antibodies soon. The IgM antibody is a general purpose antibody and shows up for many other common things. As I mentioned before; A negative results doesn't mean you do not have the virus and a positive results doesn't mean you do.

If you waited at least 12 weeks before getting tested, your IgG result should be accurate. However, for peace of mind, I would get retested with the HerpeSelect brand test at the 6 month mark past possible exposure, it's a type specific test for both HSV1 and HSV2 and FDA approved (which you first IgG I/II test isn't). LabCorp offers HerpeSelect but your doctor needs to request it by Name/code.

DO NOT have your doctor order the IgM test again.[/QUOTE]

Yes, it was Labcorp. its only been a couple of weeks since my exposure. i will check in with my doc at the 6 month mark and ask for the HerpeSelect test. Thanks for your help.
[QUOTE=over21]When I wrote my first post, my initial guess was either you had a combination IgG or the IgM. But your results wording lead me to IgM.

Was LabCorp the actual lab that did your blood work? Your negative combination IgG result is a good sign. It means at the time of the blood draw, you do not have either type of HSV. How many weeks did you wait post last possible exposure? LabCorp's default test is a non-type specific test (like the one you had). If it's positive, you're retested with the HerpeSelect ELISA test for HSV2. If this result is negative, you're assumed to have HSV1 and no further testing is done. If the result was positive, then your tested again with the HerpeSelect ELISA test for HSV1.

The IgM results are confusing and should be disregarded. The thought is these IgM antibodies show up first on an initial (first time) outbreak. After 6 months they'll dissipate as the IgG antibodies show up and take over and will be with you for the rest of your life to help fight off further infections (which is a good thing). While this thought process is true, it's not true all the time. Meaning, just because you have IgM antibodies, it doesn't mean 100% you be developing the IgG antibodies soon. The IgM antibody is a general purpose antibody and shows up for many other common things. As I mentioned before; A negative results doesn't mean you do not have the virus and a positive results doesn't mean you do.

If you waited at least 12 weeks before getting tested, your IgG result should be accurate. However, for peace of mind, I would get retested with the HerpeSelect brand test at the 6 month mark past possible exposure, it's a type specific test for both HSV1 and HSV2 and FDA approved (which you first IgG I/II test isn't). LabCorp offers HerpeSelect but your doctor needs to request it by Name/code.

DO NOT have your doctor order the IgM test again.[/QUOTE]

i spoke to the nurse practitioner this morning. she said the blood test results show that i have herpes. i asked if its possible to have the antibodies but not the virus and she said no. can you provide some citations to where you heard that the IgM antibody is a general purpose antibody and can show up for other reasons? thanks.





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