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Infertility
Jan 6, 2009
I am 31 years old now, with very irregular periods (low FSH levels) and a PCOS condition.

We conceived our first child, 3 years back, through IUI, using Humog injections (32 doses of 75IU each) and on 20th day when RO follicles were at 28mm 26mm 22mm 18mm 17mm 15mm and LO follicles were at 16mm 15mm 14mm, the HCG 10000IU was triggered. The insemination was done, 48 hrs well after the HCG trigger (22nd day), only after confirming that the follicles were ruptured in both ovaries. We successfully conceived the child.

Now we are trying to conceive our 2nd child through IUI cycle and so far we did 2 unsuccessful IUI cycles.

In the 1st IUI cycle we used Follistim (12 doses of 75IU each), injected Ovidrel (250mcg) on the 14th day when RO follicles 17mm and 14mm. Insemination was done after 36 hours on the 16th day (follicle was not ruptured at this time, which was confirmed through ultrasound) and post insemination, continued on Prometrium from 18th to 29th day.

We did the 2nd IUI cycl, after a gap of one menstrual period, using Follistim (23 doses of 75IU each) and injected Ovidrel (250mcg) on the 19th day when RO follicles 17mm and 16mm, LO follicles were at 15mm and 14mm. Insemination was done after 36 hours on the 21st day (we do not know if follicle was ruptured or not) and post insemination, continued on Prometrium from 23rd to 38th day.

Since both attempts were not successful:

~ The fellopian tube was normal when i 1st conceived is there any blocks in the fallopian tubes now?
~ Is it possible that Ovidrel might not have ruptured the follicles post insemination?
~ Is it possible that my body responds to Humog/HCG combo rather than Follistim/Ovidrel combo?
~ What should be the next step?





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