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Hi there. Thanks for responding. Luke has almost ablsent c4 levels. He was very ill in June at 16 months and they really don't know wat was wrong. That is how we found out that he has the low level. He had pancytopenia, almost absent blood levels, enlarged liver and spleen, fluid around the heart and in the abdomen, couln't walk for 2 weeks, high fever, rash and he was swollen up to twice his normal size. He had to have 2 albumin transfusions, a platelet transfusion and infused with ivig. The drs did a bone marrow to test for cancer and it showed no cancer but it did show that the bone marrow was not producing blood cells and it was inflammed. He was first diagnosed with kawasaki disease and now they don't think that is what was wrong. He has a facial rash and he gets purpleish hands and feet when he is cold and has psorisis. as for the other symptoms I don't notice any at this time. I too in anxious to see what comes out of the test results. I will let you know what happens with it.

[QUOTE=AngelicBrat]Hi Wendy!

Sorry I missed your post.. it fell to the bottom too quick! Lupus can affect children just as it does adults, it is more uncommon for kids and for boys but it sure can happen. Does he have symptoms of Lupus? Low C4 levels can indicate a lot of different things. I will be interested to hear abotu his ANA and anti-dna as well as his symptoms. This is what I just read on low serum C4.

"Very low or absent titers suggest an inherited deficiency, while diminished values may be associated with SLE or serious infection, including meningococcal meningitis (inflammation of the brain), as well as severe RA (Rheumatoid Arthritis), serum sickness( a weird reactive autoimmune response syndrome), hepatitis, acute poststreptococcal glomerulonephritis,(involving kidneys) membranoproliferative glomerulonephritis, gram-negative septicemia,(septic means the body is poisoned.. he would be VERY sick) and subacute bacterial endocarditis. (an inflammation of the heart basically).

Hope this helps a bit and hope to hear from you!


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