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This was a test to confirm Lupus but Normal titer was <1:80. With a titer of <1:160 be positive and what is Nucleolr
Hi. I'm sorry that I didn't see this & write back before now! Anyhow, ANA is only a general test that can be positive in a wide variety of conditions, not just lupus. The ANA test involves doing successive dilutions, and inspecting the sample at each point to see if "fluoresced material" still shows up. The first value reported is 1:40---and from there, 1:80, 1:160, 1:320, 1:640, etc.

While 1:160 is elevated, I don't think it 's wildly high. I'm not sure if a doctor would even count that level as positive when evaluating for lupus. (In contrast, a result of 1:1280 would be high!) I don't think there's any established rule for this, so counting (or not counting) may vary by doctor.

ANA can also elevate due to a passing infection, aging, certain meds, or because of a family tendency. i.e., it's really pretty "fuzzy", actually.

To confirm lupus, doctors instead use a pre-established list of criteria that's far more involved than just the ANA result. You may find those criteria in a "sticky post". (Those are the permanent info posts located above the user threads.) Generally, but not always, people must meet 4 or more of the 11 to be diagnosed with lupus.

When ANA is positive, lab techs determine what pattern it is, and nucleolar is one of the possible ANA patterns. But like your ANA level, ANA pattern isn't diagnostic of anything either. It's probably best viewed as a "judgment call", anyway, since it's a subjective evaluation made by a lab tech.

Was it your GP who ran these labs? If you have symptoms that could fall within lupus, I'd want to see a rheumatologist, as they're the specialists best versed in diagnosing and treating lupus. I'd also want to make sure my thyroid levels were checked too, because thyroid issues can also elevate ANA & cause some of the same symptoms as milder lupus (fatigue, joint pain, etc.)

Please let us know if this was what you were after. If not, we'll try again. Again, I'm sorry to be so slow. Sending my best wishes, Vee

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